Phytolacca americana, commonly known as pokeweed, is a large perennial plant widespread across North America. It is often found in fields, along roadsides, and in disturbed areas. Every part of the pokeweed plant, from the root to the mature berries, contains toxic compounds dangerous to both humans and pets. Ingestion of any portion can lead to significant poisoning symptoms, and the plant should be avoided entirely.
The Toxic Components and Plant Parts
The toxicity of pokeweed is primarily due to a group of compounds, including triterpene saponins and the alkaloid phytolaccatoxin, along with phytolaccigenin. These substances act as irritants, specifically targeting the gastrointestinal tract upon ingestion. The concentration of these toxins varies significantly across the plant’s structure, making some parts far more dangerous than others.
The large, fleshy taproot contains the highest concentration of toxins and is considered the most hazardous part of the plant. Following the root, the mature leaves and stems also hold high levels of the poisonous compounds. While the berries are the least toxic part, they still contain enough poison to cause severe reactions, especially if consumed in quantity or when they are still green and unripe.
Birds commonly feed on the mature, dark purple berries without apparent harm. This is because the seeds, which hold high toxin levels, often pass through the avian digestive system intact. However, this tolerance does not extend to mammals, including humans, for whom the berries remain a serious poisoning risk.
Recognizing Pokeweed
Identifying pokeweed is the first step in prevention, as it is a large, distinctive plant that can grow 4 to 10 feet tall. The most notable feature is the thick, smooth stem, which typically develops a reddish or purplish hue as the plant matures. The leaves are large, alternate, and lance-shaped, often measuring between five and ten inches long.
Pokeweed produces small, greenish-white flowers clustered along slender, drooping stems called racemes. These flowers eventually develop into the characteristic fruit, which starts as a pale green berry. The berries mature into a deep, glossy dark purple or black color, forming dense, grape-like clusters that hang from the stem.
These mature, dark berries may be confused with edible wild fruits like blueberries or elderberries, especially by small children. The purple juice from crushed berries can stain the hands and mouth, which is a common clue in suspected poisoning cases. The plant’s overall size, combined with the distinctive purple stem and hanging clusters of dark berries, makes it relatively easy to spot.
Symptoms of Ingestion and Emergency Response
Ingestion of pokeweed typically results in symptoms manifesting quickly, often within two to six hours of consumption. The immediate symptoms usually involve a burning sensation in the mouth and throat, followed by a range of severe gastrointestinal issues. These effects are the body’s reaction to the highly irritating saponins and phytolaccatoxin.
The most common signs of poisoning include persistent nausea, forceful vomiting, abdominal cramping, and severe diarrhea. This gastrointestinal distress can cause severe dehydration if fluid loss is not managed. Less common but more serious systemic effects, such as hypotension, visual disturbances, and changes in heart rate, have been reported in severe cases, especially following large ingestions.
While adult poisoning is rarely fatal, children are particularly susceptible to systemic effects from ingesting the berries due to their smaller body mass. If any part of the pokeweed plant is consumed, the immediate response is to contact the national toll-free Poison Help hotline at 1-800-222-1222. The experts at Poison Control will provide specific instructions based on the person’s age, weight, and the amount of plant material ingested.
Do not attempt to induce vomiting unless explicitly instructed by a healthcare professional or Poison Control. Medical treatment is primarily supportive, focusing on managing dehydration with intravenous fluids and controlling gastrointestinal symptoms. Seeking prompt medical attention is advised to ensure appropriate monitoring and care, especially if symptoms are severe or if a child is involved.

