Shrews are small, highly active mammals often mistaken for rodents, but they belong to a separate order of insectivores that includes some of the world’s few venomous mammals. While many familiar venomous creatures are reptiles or arachnids, a select few shrew species have evolved a toxic bite that allows them to subdue prey. This adaptation provides a distinct predatory advantage for these fast-metabolizing hunters.
The Direct Answer: Identifying Venomous Shrews
Venom is restricted to a few specific genera, most notably Blarina and Neomys. The most well-known venomous species in North America is the Northern Short-tailed Shrew, Blarina brevicauda, which is found across the eastern half of the continent. This relatively large shrew uses its toxic saliva for hunting. Other species, such as the Eurasian Water Shrew (Neomys fodiens), also possess this specialized predatory tool.
Delivery System and Toxin Composition
Venom is produced not in specialized fangs, but in modified submaxillary salivary glands located beneath the jaw. The toxic saliva then flows into the mouth and is delivered through the animal’s teeth as it bites its prey. The lower incisors of the Northern Short-tailed Shrew feature a groove that acts like a channel, guiding the venom into the wound inflicted by the bite. The shrew essentially “chews” the venom into its victim, relying on the toxin to quickly take effect.
The shrew’s venom itself is a complex cocktail of proteins, primarily a kallikrein-like protease known as blarina toxin (BLTX). This protein is responsible for the neurotoxic and paralyzing effects observed in victims. The toxin also includes components that affect the circulatory system, such as those causing blood coagulation or disrupting circulation. This potent mix allows the small shrew to quickly incapacitate animals much larger than itself.
Effects on Prey and Risk to Humans
The primary ecological role of the venom is to immobilize the shrew’s prey, which includes earthworms, insects, and small rodents like voles. Shrews have an incredibly high metabolic rate, meaning they must eat almost constantly to survive. By paralyzing a victim, the shrew can effectively store the prey in a comatose state. This hunting strategy ensures a supply of fresh, non-decomposing food for a short period, adapting to their intense caloric needs.
A bite from a venomous shrew, such as the Northern Short-tailed Shrew, is not considered medically dangerous to humans. Bites usually occur only when a person attempts to handle the animal, which is naturally aggressive when threatened. The initial bite can cause immediate pain, burning sensations, and localized swelling. The amount of venom delivered is small and does not pose a serious threat to a healthy adult. Individuals with specific allergies may experience a more severe reaction, and should seek medical attention if bitten.

