Tetrahydrocannabinol (THC) is the primary psychoactive compound in cannabis, and its potency is directly tied to its chemical stability. The compound is susceptible to thermal degradation, a chemical breakdown caused by exposure to heat that permanently alters its structure. Understanding this process is a major concern for consumers and manufacturers, as it dictates how cannabis should be processed and stored to maintain its desired effects and strength.
The Thermal Degradation Point
The temperature at which THC begins to degrade significantly is much higher than the temperature required to activate it. Raw cannabis contains Tetrahydrocannabinolic acid (THCA), which must be heated in a process called decarboxylation to convert it into the psychoactive THC. This activation typically occurs between 220°F and 245°F (105°C and 120°C), maximizing conversion with minimal product loss.
The process of destruction begins to accelerate as temperatures climb past the boiling point of THC, which is approximately 315°F (157°C). While some degradation occurs below this point over long periods, the structural integrity of the molecule is rapidly compromised at higher temperatures. Degradation becomes significant and nearly instantaneous when temperatures exceed 392°F (200°C), a range often reached during high-temperature vaporization or smoking.
What THC Becomes When It Degrades
When THC is exposed to excessive heat, it undergoes a chemical transformation into Cannabinol (CBN). This conversion is primarily a result of oxidation and dehydrogenation, where the molecule loses hydrogen atoms and gains an oxygen component. This degradation process is often visually apparent in older, improperly stored cannabis or residue that has been exposed to high heat.
The resulting CBN molecule provides a different user experience compared to THC. While THC is known for its euphoric and psychoactive effects, CBN is significantly less psychoactive and often produces a sedative, drowsy effect. This chemical change explains why highly degraded cannabis may feel less potent in terms of its intoxicating effects but may still contribute to sleepiness.
Non-Thermal Factors Accelerating Degradation
While high temperatures are the most immediate cause of degradation, THC’s stability is also compromised by non-thermal environmental factors. Exposure to oxygen is a major contributor, initiating the oxidation process that drives the conversion of THC into CBN over time, even at room temperature. This reaction is accelerated when the product is not stored in an airtight container, allowing air to interact with the cannabinoids. Ultraviolet (UV) light, such as direct sunlight, is another catalyst for photodegradation. UV rays break down the chemical bonds in the THC molecule, contributing to potency loss. Even under optimal conditions, the natural aging of the product will lead to a gradual reduction in THC content and a corresponding increase in CBN.
Storage Strategies to Maintain Potency
Translating the science of degradation into practice requires controlling the environment to minimize exposure to the three main culprits: heat, light, and oxygen. The ideal storage temperature for maintaining long-term potency is consistently cool, generally below 70°F (21°C). Temperatures above this threshold, particularly those exceeding 86°F (30°C), will significantly accelerate the breakdown of THC into CBN. For preservation, cannabis products should be stored in opaque, airtight containers to prevent oxygen exposure and photodegradation. Glass mason jars are commonly used because they provide a complete seal against air and, if kept in a dark location, block out UV light. While refrigeration is an option for short-term preservation, freezing is generally only recommended for very long-term storage of extracts, as repeated freezing and thawing can damage the delicate trichomes that contain the cannabinoids.

