Can a Heart Murmur Cause Fatigue?

A heart murmur is a sound, often described as a whooshing or swishing noise, that occurs when blood flows turbulently through the heart. This sound is distinct from the normal “lub-dub” of a heartbeat, which is created by the heart valves opening and closing. While many murmurs are completely harmless, those that signal a structural problem within the heart can indeed lead to chronic fatigue and a range of other symptoms.

Understanding Heart Murmurs

Heart murmurs are broadly categorized into two main groups: innocent and pathological. Innocent or functional murmurs are common, especially in children, and are not associated with structural heart defects. These murmurs occur when blood flows faster than usual through a normal heart, such as during periods of fever, pregnancy, or strenuous exercise, and they do not cause symptoms like fatigue.

Pathological murmurs, however, are a sign of an underlying issue, typically involving damage to the heart valves or a defect in the heart’s structure. These murmurs arise from blood flowing backward through a leaky valve (regurgitation) or struggling to get through a stiff, narrowed valve (stenosis). This compromised heart function can lead to noticeable symptoms and require medical attention.

The Mechanism Linking Murmurs to Fatigue

Fatigue develops in people with a pathological murmur because the structural problem compromises the heart’s ability to efficiently pump blood, resulting in reduced cardiac output. Cardiac output is the volume of blood the heart pumps per minute, and when it is reduced, the entire body receives less oxygenated blood than it requires to meet metabolic demands. This systemic lack of adequate oxygen delivery is sensed by the body as persistent tiredness.

In cases of valve stenosis, such as aortic stenosis, the heart must exert excessive force to push blood through a narrow opening. This increased workload causes the heart muscle to thicken over time, which eventually makes the heart inefficient and less able to pump a normal volume of blood, leading to reduced cardiac output. Conversely, in valve regurgitation, a portion of the blood leaks backward into the heart chambers, meaning the heart has to pump the same volume of blood multiple times to move it forward, causing the heart muscle to weaken and fail over time.

The heart’s inefficiency leads to heart failure, where the heart cannot keep up with the body’s needs. This condition causes reduced blood flow to the skeletal muscles, which in turn leads to a buildup of metabolic waste products and a lack of oxygen delivery. The resulting muscle fatigue and general exhaustion are often most pronounced during physical activity, but can become constant as the condition progresses.

Associated Symptoms of Serious Murmurs

Fatigue is rarely the only symptom when a pathological murmur signifies a serious underlying heart condition. When the heart struggles to pump blood forward, pressure often builds up in the blood vessels leading back to the heart, causing fluid to leak out into tissues. This fluid retention often manifests as swelling, a condition known as peripheral edema.

Shortness of breath is common, particularly when a person is exerting themselves or lying flat. This occurs because blood backs up into the lungs, causing congestion that interferes with normal oxygen exchange. Other symptoms that may accompany a serious murmur include chest pain or discomfort, heart palpitations, and episodes of dizziness or fainting, which signal severely reduced blood flow to the brain.

Clinical Evaluation and Treatment

Any murmur should be evaluated by a healthcare professional, especially if it occurs alongside symptoms like persistent fatigue or shortness of breath. The initial step involves a physical examination, where a doctor listens to the specific characteristics of the murmur, such as its timing, intensity, and pitch, to determine if it is likely innocent or pathological. If a pathological murmur is suspected, further objective testing is required to determine the structural cause.

The most informative diagnostic tool is the echocardiogram, which uses sound waves to create detailed images of the heart’s chambers, walls, and, most importantly, the function of the valves. This test allows doctors to precisely measure the severity of valve narrowing or leakage and assess the impact on the heart muscle. Additional tests, such as an electrocardiogram (EKG) and chest X-ray, may also be used to check for abnormal heart rhythms or fluid buildup in the lungs.

Treatment for a symptomatic pathological murmur focuses on addressing the underlying valve or structural problem, rather than the sound itself. Management often begins with medications, such as diuretics to reduce fluid retention or drugs to decrease the strain on the heart, aiming to control symptoms like fatigue. For murmurs caused by severe valve disease that significantly compromises heart function, a surgical intervention, such as valve repair or replacement with a prosthetic valve, may be necessary to restore efficient blood flow and resolve the debilitating fatigue.