Can an Ultrasound Detect a Stomach Ulcer?

The question of whether an ultrasound can detect a stomach ulcer is common, especially since it is a non-invasive and widely available imaging technique. A stomach ulcer, technically known as a peptic ulcer, is an open sore that develops on the inner lining of the stomach or the first part of the small intestine, called the duodenum. While abdominal ultrasound is useful for diagnosing many causes of abdominal pain, its effectiveness for directly visualizing a typical, uncomplicated peptic ulcer is significantly limited. Understanding the nature of the ulcer and the physics of ultrasound explains why other diagnostic methods are necessary.

Understanding Stomach Ulcers

Peptic ulcers are erosions that penetrate the protective mucosal lining of the gastrointestinal tract, exposing the underlying tissue to harsh stomach acid and digestive enzymes. An ulcer in the stomach is specifically called a gastric ulcer, while one in the duodenum is a duodenal ulcer. The most common cause of these sores is infection with the bacterium Helicobacter pylori (H. pylori).

The other major cause is the long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and aspirin. These medications interfere with the body’s ability to produce the protective mucus that normally shields the stomach and duodenal walls from acid. While factors like stress or spicy foods do not directly cause ulcers, they can certainly aggravate the symptoms.

Limitations of Ultrasound for Ulcer Detection

Standard external abdominal ultrasound uses high-frequency sound waves that travel easily through liquid and solid tissues, which is why it is effective for imaging organs like the liver, kidneys, and gallbladder. However, the technology is fundamentally compromised by the presence of air or gas, which scatters the sound waves and prevents them from returning a clear image. The stomach is a hollow organ that almost always contains some amount of gas and moving contents.

This gas significantly obscures the delicate inner mucosal layer where a peptic ulcer forms, making direct visualization of a small, non-perforated ulcer nearly impossible with a standard transabdominal approach. The typical ulcer is a shallow defect on the inner wall, and the sound waves cannot penetrate the gas barrier. Because of this technical challenge, the overall sensitivity of abdominal ultrasound for detecting gastric ulcers remains low.

In very specific circumstances, ultrasound may detect an ulcer, such as when the sore is exceptionally large, measuring greater than 5 millimeters in diameter. Additionally, if an ulcer has become complicated, such as a perforated ulcer that has leaked air and fluid into the abdominal cavity, the associated fluid and inflammation may be visible. However, these instances are the exception, and standard ultrasound is not recommended as a reliable first-line tool for the diagnosis of typical peptic ulcer disease.

Primary Diagnostic Methods for Peptic Ulcers

Due to the limitations of external imaging, the preferred method for diagnosing a peptic ulcer is an upper gastrointestinal endoscopy, often referred to as an EGD. This procedure involves a physician inserting a long, flexible tube equipped with a camera down the throat and into the esophagus, stomach, and duodenum. Endoscopy allows for direct, visual inspection of the lining, which can confirm the presence, location, and size of an ulcer.

During the endoscopy, the physician can also take a small tissue sample, known as a biopsy, from the edge of the ulcer. This biopsy is crucial for two reasons: it can determine if the ulcer is benign or malignant, and it allows for testing to confirm the presence of H. pylori infection. Non-invasive tests are widely used to identify the bacterial cause, including the urea breath test and stool antigen tests.

Another imaging option is the upper gastrointestinal series, also known as a barium swallow, which uses X-rays. The patient swallows a thick liquid containing barium, which coats the lining of the upper digestive tract. This contrast material makes the outline of the stomach and duodenum visible on the X-ray, allowing the physician to detect the ulcer crater. This method is often used when an endoscopy is unavailable or not the best option for the patient.

What Abdominal Ultrasound Is Used For

While it is ineffective for directly diagnosing an uncomplicated peptic ulcer, abdominal ultrasound remains a valuable diagnostic tool in the setting of upper abdominal pain. Physicians frequently order an ultrasound to rule out other common conditions that can mimic ulcer symptoms. For instance, ultrasound is the preferred method for detecting gallstones or inflammation of the gallbladder (cholecystitis), which often cause pain in the upper right side of the abdomen.

The procedure is also effective for evaluating the condition of solid organs like the liver, kidneys, and pancreas, helping to identify issues such as liver masses or pancreatitis.

Endoscopic Ultrasound (EUS)

In some advanced settings, endoscopic ultrasound (EUS) is performed. EUS involves placing a miniature ultrasound probe on the tip of an endoscope, allowing the physician to get a highly detailed image from inside the stomach wall itself. This bypasses the gas interference of external ultrasound. EUS is mainly used to determine the depth of an ulcer or to differentiate between benign and malignant lesions.