Chlamydia is a highly common sexually transmitted infection (STI) caused by the bacterium Chlamydia trachomatis. While known for affecting the genital and rectal areas, the bacteria can also infect other mucous membranes. Chlamydia can definitively be present in the mouth or throat, though this is less frequent than genital or rectal infections. This infection, known as pharyngeal Chlamydia, occurs when the bacteria colonize the pharynx, the part of the throat behind the nose and mouth.
How Chlamydia Spreads to the Throat
Transmission of Chlamydia trachomatis to the throat occurs through unprotected oral contact with an infected partner. This usually involves performing oral sex on a person who has a Chlamydia infection in their genital or rectal area. The bacteria transfer from the infected site to the mucous membranes of the mouth and throat.
The pharynx, including the back of the throat and the tonsils, is the main site where the bacteria multiply. Although the bacteria prefer the cells found in the genital tract, they can establish an infection in the oropharyngeal area. Transmission likelihood increases with the lack of barrier methods, such as dental dams or condoms, during oral contact.
The bacteria can also be transmitted from an infected throat to a partner’s genital area, completing a cycle of potential spread. This underscores the importance of considering the mouth and throat as potential sites of infection and transmission, requiring site-specific testing.
Recognizing Symptoms of Oral Infection
A significant challenge with pharyngeal Chlamydia is its tendency to be asymptomatic, meaning the infected person shows no outward signs of illness. Most individuals remain unaware unless they undergo specific testing, allowing the infection to persist and potentially spread to partners.
When symptoms do occur, they are often mild and appear one to three weeks after exposure. The clinical presentation commonly resembles pharyngitis, or a mild sore throat. This may include persistent scratchiness or general discomfort at the back of the throat.
Other possible signs include redness in the throat, swollen lymph nodes in the neck, or pain while swallowing. Subtle signs of inflammation, such as swollen tonsils or white spots, can cause the infection to be confused with a common cold or strep throat. Because these symptoms are nonspecific, they are rarely the reason a person seeks STI testing.
Diagnosis and Management
Diagnosing Chlamydia in the throat requires testing specifically designed to detect the bacteria at that anatomical site. Standard urine or genital swab tests are insufficient because the bacteria are localized in the pharynx. The proper diagnostic procedure involves taking a throat swab, which is then analyzed using a laboratory technique.
The gold standard for detection is the Nucleic Acid Amplification Test (NAAT), which identifies the genetic material (Chlamydia trachomatis DNA) with high accuracy. Requesting a pharyngeal swab is important for anyone who has engaged in unprotected oral contact, regardless of symptoms. This site-specific testing prevents an infection from being missed.
Once pharyngeal Chlamydia is confirmed, the infection is highly treatable with a short course of oral antibiotics. Standard management involves a seven-day regimen of Doxycycline, which is effective in clearing infections across various anatomical sites. An alternative treatment is a single dose of Azithromycin, though Doxycycline may be more effective for throat infections.
Following treatment, patients must abstain from sexual contact for seven full days to ensure the antibiotic has eradicated the bacteria and to prevent transmission. Management also involves the testing and treatment of all recent sexual partners. This partner notification is necessary to break the cycle of transmission and prevent reinfection.

