Can Coffee Give You Ulcers? Here’s What Science Says

Coffee is a globally consumed beverage, yet many drinkers worry whether their daily cup could be contributing to stomach problems, specifically the development of peptic ulcers. This concern often stems from coffee’s acidic nature and the uncomfortable symptoms of heartburn or indigestion some people experience. To understand this relationship, it is necessary to separate the immediate physiological effects of coffee from the long-term biological processes that lead to true ulcer formation.

Understanding the True Causes of Peptic Ulcers

A peptic ulcer is an open sore that forms on the inner lining of the stomach (gastric ulcer) or the upper part of the small intestine (duodenal ulcer). These sores develop when corrosive digestive acids erode the protective mucosal layer that normally shields the digestive tract. Ulcer formation is an imbalance between these destructive acids and the stomach’s defensive barrier.

The vast majority of peptic ulcer cases are caused by two primary factors, neither of which is coffee. The most common cause is infection with the bacterium Helicobacter pylori (H. pylori), which colonizes the mucosal layer and causes chronic inflammation. This bacteria weakens the lining and impairs the secretion of bicarbonate, making the tissue vulnerable to acid damage.

The second primary factor is the long-term, regular use of Nonsteroidal Anti-inflammatory Drugs (NSAIDs), such as ibuprofen or aspirin. NSAIDs interfere with the body’s production of prostaglandins, which stimulate the creation of protective mucus and bicarbonate. By blocking these protective mechanisms, NSAIDs expose the stomach lining to digestive acids, leading to erosion and ulcer formation.

The Physiological Impact of Coffee on the Stomach

While coffee does not cause peptic ulcers, it has an immediate impact on the gastric environment. Coffee contains a complex mixture of compounds that directly stimulate the stomach’s acid-producing cells. This action is not solely due to caffeine, as both caffeinated and decaffeinated coffee induce this response.

Components like chlorogenic acids and other organic acids trigger the release of gastrin, a hormone that signals the stomach to increase hydrochloric acid production. This surge in acid can cause uncomfortable symptoms like heartburn or acid reflux, especially in people with a pre-existing sensitivity or Gastroesophageal Reflux Disease (GERD). For individuals who already have a damaged mucosal lining, the increased acid production can exacerbate the pain.

The roasting process can influence these effects; darker roasts are less effective at stimulating gastric acid secretion compared to lighter roasts. This difference is attributed to the formation of N-methylpyridinium (N-MP) during the high-heat roasting process, which may down-regulate acid production. The physiological response to coffee is primarily an irritation or an exacerbation of symptoms, not the creation of a new ulcer.

Scientific Consensus on Coffee and Ulcer Development

Scientific research, particularly large-scale epidemiological studies, has consistently investigated the relationship between coffee consumption and peptic ulcer risk. The consensus among medical researchers is that coffee consumption is not a risk factor for the development of peptic ulcers in otherwise healthy individuals. This conclusion distinguishes between the symptomatic irritation coffee causes and the long-term biological causation of the sores themselves.

A systematic review found that coffee consumption was not associated with an increased risk of developing gastric or duodenal ulcers. For instance, a Japanese cross-sectional study analyzing thousands of healthy subjects found no association between coffee drinking and the incidence of acid-related diseases, including ulcers. This evidence suggests that the acid-stimulating effect of coffee, while real, is not sufficient to erode a healthy, protected mucosal barrier.

The scientific perspective views coffee as a gastric irritant, meaning it can trigger temporary discomfort, but not as an ulcerogen (a substance that causes ulcers). Therefore, for individuals who test negative for H. pylori and do not regularly use NSAIDs, the risk of developing a peptic ulcer from coffee is negligible.

Strategies for Sensitive Stomachs

For individuals who experience discomfort from coffee, or who have existing ulcers and wish to continue drinking it, several strategies can mitigate the gastric impact.

  • Switching to a darker roast, such as a French or Italian roast. The longer roasting time breaks down more acid-producing compounds, resulting in less acid stimulation.
  • Using the cold brewing method. Steeping coffee grounds in cold water extracts fewer acidic compounds, resulting in a cup that can be up to 70% less acidic than traditional hot brewing.
  • Drinking coffee alongside a meal. Food helps buffer and neutralize some of the increased hydrochloric acid.
  • Adding milk or cream. Dairy proteins actively bind with and buffer the acids in the coffee, further neutralizing acidity.
  • Choosing beans grown at lower altitudes.
  • Selecting decaffeinated options.