Continuous Positive Airway Pressure (CPAP) therapy is a common, effective treatment for obstructive sleep apnea, delivering pressurized air to keep the airway open during sleep. Many users report waking with throat discomfort, dryness, or irritation. This common side effect stems from the interaction between the device’s airflow and the delicate mucosal lining of the upper airway. The discomfort can range from mild scratchiness to noticeable soreness or hoarseness upon waking.
Airflow Dynamics and Mucosal Dryness
The primary cause of throat problems is the introduction of pressurized air, which can overwhelm the body’s natural humidification process. Normally, the nasal passages warm and moisten inhaled air before it reaches the sensitive tissues of the throat and lungs. The forced air from a CPAP machine, especially if unhumidified, bypasses this natural process and acts as a desiccant, actively stripping moisture from the mucous membranes.
This rapid evaporation of moisture leads to mucosal dehydration. The resulting dryness causes the tissues in the throat to become irritated, sore, or scratchy, often manifesting as a dry cough or hoarseness after removing the mask. Modern CPAP devices often include a heated humidifier, which is designed to counteract this drying effect by adding water vapor to the airflow. Proper use of heated humidification, sometimes paired with heated tubing to maintain air temperature, is the most direct way to mitigate the physical discomfort caused by dry air.
Troubleshooting Mask Fit and Device Maintenance
Mask fit issues and mouth breathing are mechanical factors that severely exacerbate throat dryness and irritation. An air leak occurs when the seal around the mask breaks, directing the pressurized air stream away from the intended path, often blowing directly across the mouth or throat. If a nasal mask is used and the user breathes through their mouth, the stream of pressurized air rushes out, rapidly drying the oral and pharyngeal tissues. Solutions often involve adjusting the physical equipment setup to ensure a closed system, such as switching to a full-face mask or employing a chin strap to keep the mouth closed.
Beyond fit, poor device maintenance can introduce irritants that inflame the throat. If the water chamber, tubing, or mask is not cleaned regularly, it can become a breeding ground for mold, bacteria, or dust, which are then delivered directly into the airway, causing irritation or infection. Using harsh cleaning agents or scented soaps can also leave residue that irritates the throat lining.
When to Consult a Sleep Specialist
While many CPAP-related throat issues are resolved through humidification and mask adjustments, persistent or severe symptoms may require professional intervention. If throat irritation continues despite optimizing the mask fit and cleaning routine, the problem may be related to the device’s pressure settings. A pressure that is too high can increase the velocity of the air, potentially increasing the drying effect. High pressure also contributes to aerophagia, where air is inadvertently swallowed, causing discomfort that can feel like throat or chest pain.
Persistent throat soreness can also be a symptom of an underlying medical condition exacerbated by CPAP therapy. Pressurized air can worsen or trigger symptoms of Gastroesophageal Reflux Disease (GERD) by pushing stomach acid up the esophagus, leading to a chemically irritated throat. Seasonal allergies or chronic sinus issues causing post-nasal drip can also irritate the throat, which the CPAP air then dries out. A sleep specialist can evaluate therapy data, recommend a pressure change, or suggest a referral to address medical issues.
Seek immediate medical attention if the throat discomfort is accompanied by persistent pain, visible blood, or symptoms of an active infection.

