Cortisol is the body’s primary hormone released in response to stress, produced by the small adrenal glands that sit atop the kidneys. It mobilizes the body’s resources for a “fight or flight” response. Chronically elevated cortisol affects many physiological systems, including those that regulate body temperature. The link between sustained high cortisol and night sweats involves complex interactions within the body’s control systems.
The Essential Role of Cortisol
Cortisol is instrumental in regulating several bodily functions, not just the stress response. It triggers the release of glucose from the liver, providing rapid energy for muscles and the brain. The hormone also influences blood pressure regulation and acts to suppress inflammation throughout the body.
Another important function of cortisol involves controlling the sleep/wake cycle, or diurnal rhythm. Cortisol levels naturally peak in the early morning, helping the body wake up, and then decline steadily throughout the day, reaching their lowest point around midnight. This rhythmic release is managed by the Hypothalamic-Pituitary-Adrenal (HPA) axis, a communication system between the brain and the adrenal glands. The HPA axis functions as a feedback loop, ensuring cortisol is released when needed and production slows once the perceived threat has passed.
The Mechanism Linking High Cortisol to Night Sweats
Chronically elevated cortisol interferes with thermoregulation, the body’s ability to regulate its temperature. The link to night sweats relates to the body’s sustained “on” state and metabolic changes. High cortisol levels continually stimulate the sympathetic nervous system, which is responsible for the physical signs of stress.
This persistent activation increases heart rate and quickens breathing, activating the sweat glands as the body attempts to cool itself down. Stress hormones like cortisol also increase overall metabolism, generating more heat. Night sweats occur when this heightened state of metabolic activity and sympathetic arousal persists into the night, overriding the body’s natural tendency to lower its temperature for sleep.
Cortisol’s normal pattern is low at night, but chronic stress can flatten this curve, causing evening cortisol to be higher than normal. This elevated nighttime cortisol can disrupt the hypothalamus, the brain region that acts as the body’s thermostat. When the hypothalamus is dysregulated, it may mistakenly sense the body is overheating and initiate a rapid cooldown sequence, resulting in a hot flash or drenching night sweat.
Sources of Chronic Cortisol Elevation
Most sustained high cortisol levels are linked to prolonged, unmanaged life stress. Psychological stressors from work, relationships, or financial worries keep the HPA axis constantly engaged, preventing cortisol from returning to baseline. Lifestyle factors also contribute significantly, as inadequate rest and sleep deprivation directly disrupt the healthy diurnal cortisol rhythm.
Intense or excessive physical training, often called overtraining, can also elevate cortisol. The body interprets intense, prolonged exertion without sufficient recovery as a survival threat. Dietary factors, such as excessive intake of caffeine, alcohol, and refined sugars, can cause spikes and sustained elevation of the hormone.
In a smaller number of cases, chronically high cortisol is caused by specific clinical conditions, primarily Cushing’s Syndrome. This disorder involves prolonged exposure to high levels of cortisol, often due to a tumor on the adrenal or pituitary gland or the long-term use of high-dose corticosteroid medications. Severe symptoms like persistent night sweats should prompt medical investigation to rule out a pathological cause like Cushing’s Syndrome.
Strategies for Managing Cortisol Levels
Reducing chronically elevated cortisol begins with targeted changes to daily habits and routines. Prioritizing consistent, high-quality sleep of seven to nine hours per night is foundational, as sleep deprivation is strongly associated with increased cortisol levels. Engaging in regular, moderate exercise is also beneficial, but extreme endurance activity or overtraining should be avoided.
Mindfulness practices, such as meditation, deep-breathing exercises, and yoga, are effective methods for calming the nervous system and reducing HPA axis activation. Dietary adjustments, including reducing caffeine, alcohol, and processed sugars, help stabilize blood sugar and prevent hormonal spikes. A balanced diet rich in whole foods, fiber, and omega-3 fatty acids supports overall hormonal regulation.
If night sweats are severe or persistent despite lifestyle changes, consulting a healthcare provider is necessary to explore underlying medical issues. A doctor may perform diagnostic tests, such as blood, saliva, or 24-hour urine tests, to accurately measure cortisol levels throughout the day. This testing helps determine if the elevation is related to stress or if a medical condition requiring specific pharmacological management is present.

