Can Multiple Sclerosis Cause Shoulder Pain?

Multiple Sclerosis (MS) is a chronic condition where the immune system attacks the protective myelin sheath surrounding nerve fibers in the central nervous system. While MS is known for symptoms like fatigue, vision problems, and mobility changes, pain is also a common experience for many individuals. Shoulder pain, specifically, can be directly or indirectly linked to the effects of MS. Understanding this connection requires looking beyond simple joint inflammation to the interplay between nerve damage and resulting mechanical strain.

Understanding Pain in Multiple Sclerosis

Pain associated with MS is categorized into two types based on its origin. Neuropathic pain is caused by demyelination and lesions occurring directly in the brain and spinal cord. This damage disrupts the normal transmission of sensory signals, causing the brain to misinterpret them as pain. Neuropathic pain is often described as a burning, tingling, stabbing, or electric-shock-like sensation, and it can occur anywhere in the body, including the arms and shoulders. Dysesthesia is a specific example, involving unpleasant, altered sensations that manifest as chronic burning or aching.

The second category is musculoskeletal pain, which occurs as a secondary consequence of MS symptoms. This pain is caused by the strain, misalignment, and overuse of the body’s structure, rather than the nerve lesions themselves. When symptoms like muscle weakness or spasticity change how a person moves or holds their body, the joints, ligaments, and tendons take on unnatural stress. This mechanical strain is the most frequent cause of shoulder discomfort in people with MS.

Secondary Mechanisms Linking MS Symptoms to Shoulder Injury

The primary symptoms of MS often create physical changes that predispose the shoulder joint to injury and chronic pain. Spasticity, an involuntary stiffness or tightness of muscles, is a major contributor to mechanical issues. Chronic tightening of muscles in the chest, back, and upper arm can pull the shoulder joint out of alignment. This uneven tension places abnormal pressure on the rotator cuff tendons and the bursa, potentially leading to conditions like shoulder impingement or tendonitis. Even mild spasticity can cause ongoing muscle imbalance, restricting the shoulder’s range of motion and accelerating wear and tear on the joint cartilage.

Muscle weakness and fatigue further compound this problem by reducing the stability provided by the muscles surrounding the shoulder. When stabilizing muscles tire quickly, larger muscles must compensate, leading to overuse injuries. This weakness often results in poor posture, as the individual may slump or hold their arm awkwardly to conserve energy, straining the shoulder capsule.

Reliance on mobility aids, such as canes, crutches, or walkers, also introduces asymmetrical strain. The repetitive force of pushing down or bearing weight unevenly on a device can lead to bursitis or tendonitis in the weight-bearing shoulder. For those who use wheelchairs, improper positioning or repetitive transfers can also stress the shoulder joint and the surrounding soft tissues, increasing the risk of injury over time.

Distinguishing MS-Related Pain from Common Musculoskeletal Issues

A person with MS is susceptible to the same common injuries as anyone else, such as those caused by sleeping awkwardly or athletic activity. Determining the source of shoulder pain is important for effective management. Neuropathic pain linked directly to MS often presents with signs like a burning, electric, or constant tingling sensation that may not relate to movement. This discomfort can also be bilateral, affecting both shoulders simultaneously due to a spinal cord lesion.

Pain caused by secondary musculoskeletal issues typically feels like a deep ache, a sharp catch, or a strained feeling that worsens with specific movements. This mechanical pain is often localized to the joint and may be accompanied by tenderness when touching the muscles or tendons. Pain from an orthopedic issue like rotator cuff tendonitis is usually felt when lifting the arm overhead or reaching behind the back.

Because symptoms can overlap, a precise diagnosis requires a comprehensive evaluation by a healthcare team. A neurologist assesses for neurological signs, while a physical therapist evaluates posture, muscle strength, and joint mechanics. Understanding whether the pain is a misfiring nerve signal or a strained tendon dictates the appropriate treatment path.

Strategies for Managing Shoulder Discomfort

Management of shoulder discomfort linked to MS requires a multi-faceted approach addressing both underlying neurological symptoms and resulting mechanical issues. Physical therapy is a core strategy, focusing on specific exercises to strengthen the stabilizing muscles of the shoulder. Therapists also provide gentle stretching routines to counteract spasticity on the chest and back muscles, helping restore proper joint alignment.

Pharmacological interventions are tailored to the specific type of pain experienced. For musculoskeletal pain involving inflammation, non-steroidal anti-inflammatory drugs (NSAIDs) may be recommended to reduce localized swelling and discomfort. If the pain is driven by spasticity, muscle relaxants, such as baclofen or tizanidine, can help calm the involuntary muscle tightening.

For neuropathic pain, medications like anticonvulsants or certain antidepressants stabilize the nerve signals originating from the central nervous system. Ergonomic adjustments are also necessary to reduce strain on the shoulders. This includes ensuring that mobility aids are correctly fitted to the user’s height and that seating promotes a neutral, supported posture to minimize compensation.