Strep throat, caused by Group A Streptococcus, and a yeast infection, typically caused by the fungus Candida albicans, are distinct types of infections. The Strep bacteria itself does not directly cause a yeast infection. However, the medication used to treat the bacterial Strep infection often leads to fungal yeast overgrowth. Antibiotics prescribed for Strep disrupt the body’s natural microbial balance, creating an environment where Candida can multiply unchecked. This subsequent fungal infection is a common, indirect side effect of the necessary antibacterial treatment.
Understanding Bacteria and Fungus
The pathogens responsible for these two conditions are fundamentally different life forms. Streptococcus is a bacterium, a single-celled prokaryotic organism that lacks a nucleus. Bacterial infections, such as Strep throat, are treated with medications designed to specifically target and destroy these organisms.
Candida, the organism responsible for yeast infections, is a fungus, which is a eukaryotic organism more closely related to human cells. Fungi are structurally more complex than bacteria, and they require a different class of medication, known as antifungals, for treatment. This difference explains why antibiotics, which target bacteria, are ineffective against a fungal infection like yeast. The two types of microbes naturally compete with each other for resources and space within the body.
The Antibiotic Connection to Yeast Overgrowth
The primary reason a yeast infection often follows Strep treatment lies in the broad action of the prescribed antibiotics. Medications such as penicillin or amoxicillin are broad-spectrum, meaning they are designed to kill a wide range of bacteria. The drug successfully eliminates the harmful Strep bacteria, resolving the initial infection.
However, these broad-spectrum drugs do not differentiate between pathogenic bacteria and the beneficial bacteria that naturally colonize the body. The body’s natural flora, or microbiome, includes bacteria like Lactobacillus, which maintain a slightly acidic environment in areas like the vagina. This acidity and the presence of these beneficial bacteria normally keep the naturally occurring Candida fungus population in check through competition.
When the antibiotic wipes out significant numbers of the competing beneficial bacteria, the body’s microbial balance is disrupted, leading to dysbiosis. With the Lactobacillus population diminished, the environment becomes less acidic and the competition for resources is removed. This allows the Candida fungus, which is unaffected by the antibiotic, to multiply rapidly and overgrow. The resulting fungal overgrowth manifests as a yeast infection, such as oral thrush or vaginal candidiasis. The risk of developing this secondary fungal infection after taking antibiotics is estimated to be between 10% and 30%.
Prevention and Treatment of Secondary Yeast Infections
Recognizing the first signs of a secondary yeast infection is the first step toward effective management. Symptoms include intense itching, a burning sensation, and irritation. Vaginal infections are often accompanied by a thick, white, cottage cheese-like discharge. If symptoms appear, continue taking the antibiotic to treat the Strep, but contact a healthcare provider for guidance on treating the fungal infection.
Preventative steps can mitigate the risk of Candida overgrowth during antibiotic treatment. Some people choose to take probiotic supplements containing strains like Lactobacillus to replenish beneficial bacteria. It is important to take probiotics at least two to three hours apart from the antibiotic dose to prevent the drug from immediately killing them.
Dietary adjustments can reduce the food source for the yeast, as Candida thrives on sugar. Temporarily reducing the intake of refined sugars and processed foods may limit the fungus’s ability to multiply. Wearing loose-fitting clothing and breathable cotton underwear can also prevent the warm, moist environment that encourages fungal growth.
If a yeast infection occurs, over-the-counter antifungal treatments, such as creams or suppositories, are available to control the fungal overgrowth. For more persistent or severe cases, a doctor may prescribe an oral antifungal medication. Consult a healthcare professional for a confirmed diagnosis, as other conditions can present with similar symptoms.

