Chlamydia trachomatis is the most common bacterial sexually transmitted infection (STI) globally, often affecting young adults. It is characterized by its ability to spread easily during sexual contact, yet remain undetectable without testing for long periods. A diagnosis of chlamydia while in a relationship with only one partner is possible and surprisingly common. This situation does not necessarily indicate recent infidelity, but rather reflects the unique, often silent nature of the bacteria.
Defining Chlamydia Transmission Routes
Chlamydia is transmitted through the exchange of infected bodily fluids, such as semen, pre-ejaculate, and vaginal secretions, during sexual activity. Transmission occurs through contact with the mucous membranes lining the genitals, anus, or mouth. This includes vaginal, anal, and oral sex with an infected partner. Ejaculation does not need to occur for the bacteria to be passed from one person to another.
The infection can take hold in various anatomical sites, including the rectum, throat, and eyes. Eye infections, for instance, can happen if infected genital fluids are transferred to the eyes, such as by touching them with a contaminated hand. The bacteria cannot be transmitted by hugging, sharing food or drinks, kissing, or sitting on a toilet seat.
The pathway of infection requires direct contact between the bacteria and the body’s mucous membranes. Understanding this specific transmission route helps clarify the circumstances surrounding a diagnosis.
Asymptomatic Infection
The most common reason for a chlamydia diagnosis in a seemingly monogamous relationship lies in the infection’s ability to remain symptom-free for an extended time. Chlamydia is often called a “silent infection” because the majority of people who have it do not experience any noticeable symptoms. Up to 70% to 80% of infected women and about 50% of infected men are asymptomatic. This high rate of silent carriage allows the infection to spread unknowingly.
The incubation period, which is the time from exposure to when symptoms might appear, typically ranges from 7 to 21 days. Because symptoms often never develop, a person can carry the bacteria for months or even years without realizing they are infected. A new positive test result may therefore stem from an exposure that occurred with a previous partner who was also asymptomatic.
The bacteria are still highly transmissible during this asymptomatic period. When a person finally gets tested, the diagnosis simply confirms the presence of the bacteria, not the exact timing of the initial exposure. This lack of symptoms is why regular screening is so important, especially for young, sexually active individuals, as it prevents long-term complications like pelvic inflammatory disease.
Testing and Diagnosis Timeline
Diagnosing a chlamydia infection relies on highly sensitive laboratory methods. The preferred method for detection is the Nucleic Acid Amplification Test (NAAT), which identifies the bacteria’s genetic material. NAATs can be performed using a simple urine sample for men and women, or a self-collected vaginal swab for women, which is often considered the most sensitive sample type.
Timing the test correctly is important to ensure an accurate result and avoid a false negative. After a potential exposure, there is a necessary waiting period, known as the window period, before the test can reliably detect the bacteria. For chlamydia, this period is generally recommended to be at least 5 to 14 days, or up to three weeks post-exposure.
Routine screening remains the most effective strategy for controlling the spread of this silent infection. Annual testing is generally recommended for sexually active women under the age of 25, as well as for individuals with a new partner or multiple partners. Testing is also performed on other anatomical sites, such as the rectum and throat, if contact occurred there, using specific swabs.
Treatment and Preventing Re-infection
Fortunately, chlamydia is easily curable with a short course of antibiotics. Standard treatment regimens typically involve a single, high dose of azithromycin or a seven-day course of doxycycline. The entire course of medication must be completed, even if symptoms begin to clear before the final dose. The infected person must also abstain from sexual activity for seven days after starting the treatment to prevent transmission and re-infection.
Partner notification and simultaneous treatment are necessary to prevent the infection from being passed back and forth, sometimes called “ping-pong” infection. Any current or recent sexual partners must be tested and treated promptly, regardless of whether they show symptoms.
A re-test is recommended for the treated individual, typically three months after completing the initial treatment. This re-testing is primarily intended to detect re-exposure rather than treatment failure.

