A chest tube is a flexible plastic tube inserted through the chest wall and into the space between the lungs and the ribcage, called the pleural space, to drain air, blood, or fluid that shouldn’t be there. It is one of the most common emergency and surgical procedures performed in hospitals, used after trauma, lung surgery, and certain infections. The concept dates back to Hippocrates, though modern closed drainage systems only emerged in the 19th century to prevent air from flowing back into the chest and to reduce infection.
Why the Pleural Space Matters
Your lungs don’t attach directly to the inside of your ribcage. They sit inside a double-layered membrane called the pleura, and between those two layers is a thin film of fluid that lets the lungs glide smoothly as you breathe. The pressure in that space is slightly negative compared to the outside atmosphere, which is what keeps your lungs inflated. The opposing elastic forces of the lung (which wants to collapse inward) and the chest wall (which wants to spring outward) maintain that pressure balance.
When something disrupts this balance, problems follow quickly. Air leaking in (pneumothorax) neutralizes the negative pressure and lets the lung collapse. Blood pooling in the space (hemothorax) compresses the lung from below. Infected fluid (empyema) or other effusions can do the same. In all of these situations, the fundamental goal of a chest tube is the same: restore normal pressure dynamics by removing whatever has accumulated where it shouldn’t be.
When a Chest Tube Is Needed
The most common reasons for chest tube placement fall into a few broad categories. Traumatic injuries to the chest, whether from blunt force like a car accident or penetrating injuries like stab wounds, frequently cause bleeding or air leaks into the pleural space. Spontaneous pneumothorax, where the lung collapses without obvious injury (often in tall, thin young adults or people with underlying lung disease), is another frequent indication. After lung surgery, chest tubes are placed routinely to drain any residual air or fluid while the surgical site heals. Pleural effusions, which are buildups of fluid from infections, cancer, or heart failure, sometimes require drainage when they grow large enough to impair breathing.
The urgency varies widely. A tension pneumothorax, where trapped air progressively builds pressure and compresses the heart and opposite lung, is a life-threatening emergency requiring immediate decompression. A small, stable pneumothorax might be watched without any tube at all. The clinical judgment about when to intervene depends on the size of the problem, how fast it’s progressing, and how well you’re breathing.
How the Tube Gets Placed
The standard insertion site is along the side of the chest, typically between the fourth and sixth ribs, in an area sometimes called the “safe triangle.” This zone avoids major blood vessels, the heart, and the diaphragm. Identifying the right spot matters because the diaphragm sits higher than many people realize, and inserting too low risks puncturing the liver or spleen. A recent study comparing different body landmarks for identifying the correct rib space found that using the mid-sternum as a reference point avoided the diaphragm in over 90% of patients on the right side, outperforming the traditional fifth-rib-space method.
For a traditional large-bore tube, the skin is cleaned and numbed with local anesthetic. A small incision is made, and the tissue is bluntly dissected (spread apart rather than cut) down to the pleura. The surgeon or emergency physician then pushes through the pleural membrane with a finger or clamp and guides the tube into place. You might hear this called a “tube thoracostomy.” The tube is sutured to the skin and connected to a drainage system. The whole process can take just a few minutes in experienced hands, though it is not a painless experience even with local anesthesia.
Ultrasound guidance has become increasingly common, particularly for smaller tubes and non-emergency situations. A retrospective analysis of ultrasound-guided small-bore drain placement on an internal medicine ward found that the technique improved accuracy and reduced complications like accidental lung puncture and vascular injury.1PubMed Central. Ultrasound-guided small-bore chest drain placement: a retrospective analysis of feasibility, safety and clinical implications in internal medicine ward In trauma settings where speed is critical, ultrasound may not always be practical, but for planned procedures it adds a meaningful layer of safety.
Big Tubes Versus Small Tubes
One of the more active debates in chest tube management is whether you actually need a large-bore tube. Traditional teaching held that bigger tubes drain better, especially for blood, which is thicker than air or serous fluid. Large-bore tubes typically range from 28 to 36 French (a unit of catheter diameter), while small-bore options, including pigtail catheters, run from about 8 to 14 French. The evidence, however, has shifted considerably.
A meta-analysis of randomized controlled trials comparing small and large chest tubes in traumatic hemothorax, hemopneumothorax, and pneumothorax found no significant difference in failure rates between the two sizes. The tubes stayed in place for a shorter period in the small-bore group, with no difference in complication rates or length of hospital stay.2PubMed Central. Small versus large bore chest tube in traumatic hemothorax, hemopneumothorax, and pneumothorax: a meta-analysis of randomized controlled trials with trial sequential analysis A retrospective study of 95 patients with pneumothorax similarly found comparable treatment success rates between large and small tubes, with the large-bore group requiring significantly more pain medication.3PubMed Central. Small-bore vs. large-bore chest tubes for pneumothorax: a retrospective study
A systematic review looking specifically at small-bore intercostal catheters versus large-bore tubes found that pain was substantially worse with the larger tubes. Nearly all patients with large-bore tubes needed pain medication, including opioids, with a mean duration of analgesia of about eight days. Only around 40% of small-bore patients needed analgesia at all, with a mean duration of two days. Failure rates were actually slightly lower with small-bore tubes, and the rate of patients ultimately needing surgery was significantly lower in the small-bore group.4PubMed Central. The effectiveness of small-bore intercostal catheters versus large-bore chest tubes in the management of pleural disease with the systematic review of literature
For spontaneous pneumothorax specifically, a randomized trial comparing a 14-French pigtail catheter to a 28-French chest tube found a slightly higher success rate with the pigtail (about 86% versus 76%), though the difference wasn’t statistically significant. Procedure time was significantly shorter with the pigtail, and patients reported less pain during both insertion and removal, with lower analgesic use overall.5PubMed Central. Comparison of the Therapeutic Effects of a Pigtail Catheter and Chest Tube in the Treatment of Spontaneous Pneumothorax: A Randomized Clinical Trial Study A review of the broader evidence in trauma concluded that pigtail catheters, in experienced hands, appear comparable in safety and efficacy to traditional chest tubes for non-emergent cases, with improved pain scores.6PubMed Central. Minimally invasive management of thoracic trauma: current evidence and guidelines
The upshot is that for many patients, a smaller tube works just as well and hurts considerably less. Large-bore tubes still have their place in situations where rapid drainage of large volumes of blood is needed, such as massive hemothorax in a trauma bay, but the blanket preference for big tubes has softened.
Pain During and After the Procedure
Chest tube insertion has a reputation as one of the more painful bedside procedures, and that reputation is earned. Even with local anesthesia, the moment of pushing through the chest wall and into the pleural space can be intensely uncomfortable. The pain doesn’t stop after insertion either; the tube sitting between the ribs irritates surrounding nerves, and every breath can move the tube slightly against sensitive tissue.
One approach to improving pain control is the intercostal nerve block, where anesthetic is injected around the nerves running along the ribs near the insertion site. A randomized trial found that intercostal nerve block significantly reduced pain during insertion and for at least six hours afterward, with patients needing substantially less opioid medication compared to standard local anesthesia alone.7International Journal of Surgery Open. Comparison of intercostal nerve blockage versus local anesthesia for tube thoracostomy insertion; a randomised controlled trial Another trial in trauma patients performed with the patient lying flat found more modest pain reductions that didn’t reach statistical significance during the procedure itself, though there was a trend toward less pain in the hour afterward.8Journal of Emergency Practice and Trauma. Intercostal Nerve Block in Supine Position for Urgent Tube Thoracostomy in Trauma Patients: A Randomized-Controlled Study The difference likely reflects how hard it is to perform a precise nerve block in an emergency when the patient is lying flat and in distress. In a more controlled setting, nerve blocks appear to offer real benefit.
Beyond the technique used for anesthesia, tube size is the single biggest modifiable factor in pain, as the tube-size studies above consistently demonstrate. If your situation doesn’t demand a large-bore tube, a smaller one will make the experience significantly more bearable.
What’s on the Other End of the Tube
The tube doesn’t just hang off the side of the bed. It connects to a drainage system that serves several purposes at once: collecting whatever comes out of your chest, preventing air from traveling back up the tube into your pleural space, and sometimes applying gentle suction to help re-expand the lung. Traditional systems use three connected chambers: one collects fluid, one creates a water seal (a one-way valve that lets air out but not in), and one controls the level of suction. These days, these chambers are built into a single disposable plastic unit rather than the old glass-bottle setup.9PubMed. Chest Tube Drainage Devices
Digital drainage systems are an increasingly popular alternative. Instead of bubbling water to indicate air leaks, these devices use electronic sensors to continuously measure airflow and display it numerically. The potential advantage is more objective monitoring: rather than a nurse eyeballing whether the water-seal chamber is still bubbling, the device tracks the exact rate of air leak over time. A systematic review found that digital systems led to shorter chest tube duration in some studies and shorter hospital stays in others, but the majority of studies showed no significant difference in either outcome after lung surgery. The evidence was somewhat stronger for spontaneous pneumothorax, where the limited data suggested digital drainage did reduce both tube time and hospitalization.10CHEST. Digital Versus Analog Pleural Drainage Systems: A Systematic Review and Meta-Analysis Digital systems do provide a more objective record of air leak resolution, which can help guide decisions about when to remove the tube.11European Journal of Cardio-Thoracic Surgery. Digital pleural versus analog drainage devices for postoperative management of patients after pulmonary resection
Complications and What Can Go Wrong
The most common complication of chest tube placement is malposition, meaning the tube ends up somewhere other than the open pleural space where it belongs. A prospective study using CT scans to check tube position in critically ill patients found that 30% of tubes placed by the percutaneous (needle-and-wire) technique were malpositioned. The most frequent problem was the tube sitting inside a fissure between lung lobes (about 21%), followed by the tube penetrating into lung tissue itself (about 9%).12Anesthesiology. Incidence of Chest Tube Malposition in the Critically Ill: A Prospective Computed Tomography Study A trauma-focused study found tubes were correctly positioned in the pleural space only 58% of the time, with intrafissural placement in 27% and intraparenchymal in 11%.13PubMed. Clinical consequences of chest tube malposition in trauma resuscitation: single-center experience That said, the trauma study found that patient outcomes were comparable regardless of whether the tube was malpositioned, suggesting many malpositions are clinically tolerable. Rare but serious misplacements into the abdomen, heart, or major blood vessels have been reported in case literature.14PubMed Central. Unusual Malposition of a Chest Tube, Intrathoracic but Extrapleural
Re-expansion pulmonary edema is a less common but potentially dangerous complication. When a lung that has been collapsed for a while suddenly re-inflates, the damaged blood vessels in the lung tissue can leak fluid into the airspaces. Risk factors include being younger than 40, having a large pneumothorax (over 30% of the lung collapsed), symptoms lasting more than three days before treatment, and rapid re-expansion of the lung.15PubMed Central. Severe re-expansion pulmonary edema after chest tube insertion for the treatment of spontaneous pneumothorax: A case report A meta-analysis confirmed that smoking history, longer symptom duration, and larger pneumothorax size were all significantly associated with this complication.16PubMed Central. Risk factors for re-expansion pulmonary edema following chest tube drainage in patients with spontaneous pneumothorax: A systematic review and meta-analysis This is one reason why clinicians sometimes clamp tubes intermittently or drain large effusions slowly rather than all at once.
Antibiotics and Trauma
Whether to give preventive antibiotics when placing a chest tube after trauma has been debated for years. The concern is that the tube creates a direct pathway from the skin into the chest cavity, potentially introducing bacteria, especially in a chaotic emergency setting where sterile technique may not be perfect. The evidence now leans toward giving them, at least in penetrating injuries.
A systematic review and meta-analysis found that prophylactic antibiotics after chest drain insertion in trauma patients reduced the risk of empyema by about 75% and pneumonia by about 59% compared to placebo. The incidence of empyema dropped from roughly 7% without antibiotics to 1% with them.17PubMed Central. Use of prophylactic antibiotic in preventing complications for blunt and penetrating chest trauma requiring chest drain insertion: a systematic review and meta-analysis A practice management guideline from the Eastern Association for the Surgery of Trauma similarly found a significant reduction in empyema with antibiotic prophylaxis, with the benefit being particularly strong in penetrating trauma. For blunt trauma, the benefit didn’t reach statistical significance.18Trauma Surgery & Acute Care Open. Antibiotic prophylaxis for tube thoracostomy placement in trauma: a practice management guideline from the Eastern Association for the Surgery of Trauma The upshot: if you’ve been stabbed and need a chest tube, a short course of antibiotics is well supported. For blunt trauma, the case is weaker but some centers still give them.
When the Tube Comes Out
Deciding when to remove a chest tube depends on what it was placed for. For a pneumothorax, the tube typically stays until the air leak has stopped and a chest X-ray confirms the lung has re-expanded. For fluid drainage, removal happens once output drops below a threshold, often around 150 to 200 milliliters per day, though practices vary. After lung surgery, surgeons look for both cessation of air leak and acceptable fluid output.
There’s long been a minor debate about whether to pull the tube out at the end of a deep breath in or at the end of a breath out. The theory behind end-expiration removal is that the pleural space is smallest then, reducing the chance of air sneaking in as the tube slides out. A systematic review and meta-analysis found no significant difference in recurrent pneumothorax rates or tube reinsertion rates between the two techniques. Interestingly, hospital stay was shorter in patients whose tubes were removed at end-inspiration.19PubMed Central. Thoracostomy tube withdrawal during latter phases of expiration or inspiration: a systematic review and meta-analysis In practice, most clinicians have a preferred technique and the difference appears to be clinically negligible.
Delivering Medications Through the Tube
A chest tube isn’t only a passive drain. In complicated pleural infections where pus has become walled off into pockets (a condition called loculated empyema), simply letting gravity and suction do the work often isn’t enough. The fluid gets too thick and compartmentalized for a tube to clear on its own. This is where intrapleural enzyme therapy comes in.
A landmark randomized trial tested combinations of two agents instilled directly through the chest tube: tissue plasminogen activator (tPA), which breaks down fibrin strands that form the walls of the pockets, and DNase, which breaks down the DNA released from dead white blood cells that makes the fluid viscous. Used together, the combination significantly improved drainage of the infected fluid, reduced surgical referrals from about 16% to 4%, and cut hospital stay by nearly a week compared to placebo. Neither agent worked well on its own.20PubMed. Intrapleural Use of Tissue Plasminogen Activator and DNase in Pleural Infection A subsequent observational series of over 100 patients confirmed the effectiveness, including when used as a rescue therapy after antibiotics and drainage alone had failed.21PubMed Central. Intrapleural tissue plasminogen activator and deoxyribonuclease therapy for pleural infection
In clinical practice, a single-center experience treating 73 patients with tPA/DNase found a success rate over 90%, with most patients responding in fewer than six doses. The volume of fluid drained jumped dramatically after treatment, from a median of about 295 milliliters in the day before treatment to over 1,100 milliliters in the 72 hours following.22Annals of the American Thoracic Society. Concurrent Intrapleural Instillation of Tissue Plasminogen Activator and DNase for Pleural Infection. A Single-Center Experience This approach has become a standard alternative to surgery for complicated pleural infections that don’t respond to antibiotics and basic drainage.
Going Home With a Chest Tube
The traditional model has been to keep patients hospitalized as long as a chest tube is in place, which can mean days of waiting for an air leak to seal or fluid output to drop. Ambulatory chest drain management challenges that model. Using compact, portable drainage devices, some patients with primary spontaneous pneumothorax can be discharged and managed as outpatients.
A randomized trial comparing ambulatory management to standard inpatient care for primary spontaneous pneumothorax found that patients managed on an outpatient basis had a median hospital stay of zero days in the first 30 days, compared to four days for standard care. The trade-off was an increase in adverse events in the ambulatory group.23The Lancet. Ambulatory management of primary spontaneous pneumothorax: an open-label, randomised controlled trial The approach isn’t for everyone. It works best in otherwise healthy patients with uncomplicated pneumothorax who can reliably follow up, and it requires access to a portable device and clear instructions on warning signs. But for the right patient, it transforms what used to be a multi-day hospitalization into something closer to a same-day procedure.
Chest Tubes in Newborns and Children
Chest tubes in neonates present unique challenges because of the small anatomy involved. Premature infants on ventilators can develop pneumothorax as a complication of positive pressure ventilation, and tube sizes shrink accordingly, often to 8 or 10 French. The safe triangle remains the standard insertion zone, but the margin for error is much smaller. Neonatal chest tube placement is considered one of the essential intensive care procedures for this age group, sitting alongside umbilical catheterization and lumbar puncture on the list of core skills for neonatal care providers. The principles are the same as in adults (drain air or fluid, restore negative pressure), but the execution demands particular precision given how close together thoracic structures are in a body that may weigh under a kilogram.

