Cod liver oil (CLO) is a nutritional supplement extracted from the liver of the Atlantic cod, Gadus morhua. Historically used as a traditional remedy, it gained prominence in the 19th and early 20th centuries. The oil is recognized for its unique combination of two fat-soluble vitamins, Vitamin A and Vitamin D, along with a significant concentration of Omega-3 fatty acids. This nutrient profile sets cod liver oil apart from standard fish oil supplements derived from the flesh of other oily fish species. It is valued for its ability to support various bodily functions through its mixture of naturally occurring micronutrients.
Natural Origin and Nutrient Composition
Cod liver oil is sourced specifically from the liver of the Atlantic cod, which acts as a storage organ for fat-soluble compounds. This natural origin explains why the oil is inherently rich in Vitamins A and D, unlike oils extracted from the body tissues of fish. The oil consists of polyunsaturated fats, primarily the Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These Omega-3s typically comprise about 20% of the oil’s total volume.
The distinct feature of CLO is its high concentration of pre-formed Vitamin A and Vitamin D. A single tablespoon often contains approximately 4,080 micrograms of Vitamin A and about 34 micrograms of Vitamin D (1,360 International Units). This natural pairing of fat-soluble vitamins is important because the two micronutrients are known to interact within the body. However, the high amount of Vitamin A requires careful consideration when determining consumption levels.
Systemic Health Contributions
The combination of Omega-3 fatty acids and fat-soluble vitamins in cod liver oil provides broad support across several major organ systems.
Skeletal Support
One of the best-known benefits relates to skeletal support, largely driven by the Vitamin D content. Vitamin D plays a direct role in regulating the body’s absorption of calcium and phosphorus, which are necessary for the mineralization and maintenance of strong bones. Historically, this property was leveraged to prevent and treat conditions like rickets, a softening of bones in children caused by severe Vitamin D deficiency.
Immune Regulation
The oil’s components also contribute significantly to immune regulation and function. Vitamins A and D work together to support both the innate and adaptive branches of the immune system. The Omega-3 fatty acids, EPA and DHA, help modulate the body’s inflammatory response by suppressing proteins that promote chronic inflammation. Regular consumption of CLO can lead to a measurable reduction in inflammatory markers, such as C-reactive protein (CRP).
Cardiovascular Function
Cardiovascular function is supported by the high levels of EPA and DHA found in the oil. These Omega-3s are well-established for their role in promoting heart health, primarily through their effect on blood lipid profiles. They can significantly reduce blood triglyceride levels, with reductions often observed in the range of 15% to 30% with consistent use. Furthermore, the fatty acids contribute to vascular health by supporting blood vessel elasticity and helping to maintain healthy blood pressure levels. The intake of cod liver oil may also help raise levels of high-density lipoprotein (HDL) cholesterol, often referred to as “good” cholesterol, which aids in transporting excess cholesterol away from the arteries. The anti-inflammatory properties of both the Omega-3s and the antioxidant Vitamins A and D further protect the circulatory system against chronic stress. Through these multiple actions, the nutrient blend in CLO provides a foundation for maintaining systemic wellness.
Dosage, Safety, and Monitoring
Safe consumption of cod liver oil requires careful attention to the concentration of all its active ingredients, especially the fat-soluble vitamins. While there are no universal guidelines, a common daily intake for adults is often between one and two teaspoons. Consumers must check product labeling, as the exact concentration of Vitamin D varies among different brands and formulations.
The primary safety concern is the risk of hypervitaminosis A, or Vitamin A toxicity. A single tablespoon of CLO can contain Vitamin A levels (approximately 4,080 mcg) that exceed the adult Tolerable Upper Intake Level (UL) of 3,000 micrograms per day. Taking too much cod liver oil in an effort to maximize Vitamin D intake can inadvertently lead to excessive accumulation of Vitamin A in the liver. Symptoms of chronic Vitamin A toxicity can include severe headache, blurred vision, dizziness, and coordination problems.
Due to its Omega-3 content, cod liver oil can exhibit a mild blood-thinning effect, which may increase the risk of bleeding in some individuals. People taking prescription blood thinners, such as warfarin, should consult a healthcare provider before beginning supplementation to avoid potential drug interactions. Individuals with diabetes should also monitor their blood sugar closely, as fish oils may influence glucose metabolism.

