Gel manicures are popular cosmetic procedures, offering a durable, chip-resistant finish that can last for weeks. This longevity is achieved by applying a formulated gel polish and then placing the hand under a curing lamp to rapidly harden the layers. As these long-lasting manicures have grown in popularity, concerns have arisen regarding the safety of the instruments and ingredients used. The central question for many consumers is whether this beauty practice poses a significant health threat, particularly concerning an increased risk of cancer.
Understanding UV Curing Lamps
The strength of gel manicures comes from ultraviolet (UV) curing lamps, which initiate polymerization. These devices, using fluorescent bulbs or LEDs, primarily emit UVA radiation. UVA light penetrates deeply into the skin and contributes to aging and skin cancer risk. The emitted wavelengths (340 to 400 nanometers) are the same spectrum found in the sun’s rays and tanning beds. Although exposure time is brief, the proximity of the skin to the light source means the UV intensity delivered to the hands can be highly concentrated.
Scientific studies show a wide range of irradiance among salon lamps, sometimes varying from 0.6 to 15.7 milliwatts per square centimeter. This variability makes assigning a single risk factor difficult, but the overall risk relates to cumulative exposure over time. While the total dose received during a single manicure is much lower than a tanning bed session, the dose received by the fingers per area may be comparable to the recommended daily limit for outdoor exposure. The DNA damage threshold for skin cells from UVA radiation is estimated to be around 60 Joules per square centimeter.
A person would need hundreds of sessions at the lowest lamp settings to reach the DNA damage threshold, suggesting a low risk per visit. However, the primary concern is the effect of repeated exposure over a lifetime. UV damage is cumulative, contributing to photoaging and oxidative stress, and UVA exposure is a known risk factor for skin damage.
Chemical Exposure and Ingredient Safety
The chemical composition of the gel polish presents a separate set of health considerations beyond the curing light. Gel polishes contain acrylates and methacrylates, compounds necessary for the polish to polymerize and harden under UV light. Examples include Hydroxyethyl Methacrylate (HEMA) and Ethyl Methacrylate (EMA). While these chemicals are not classified as carcinogens, they pose a considerable risk for sensitization and allergic reactions.
Allergic contact dermatitis is the most frequently reported adverse reaction to these ingredients. It manifests as an itchy, painful rash that can appear on the fingertips, around the nail bed, or in distant areas like the face or eyelids. This reaction occurs when uncured gel polish is improperly applied and makes direct contact with the surrounding skin. The risk is elevated with at-home kits or when technicians lack proper training, leading to uncured polish residue.
Developing an allergy to methacrylates can have far-reaching consequences beyond cosmetic discomfort. Once sensitized, a person may become unable to tolerate products containing these chemicals, including those used in common medical and dental procedures. These compounds are found in materials for dental fillings, bone cements for joint replacements, and some contact lenses. Therefore, avoiding skin contact with the uncured polish is a crucial safety measure to prevent a severe, lifelong allergy.
The Scientific Consensus on Cancer Risk
Current scientific consensus suggests that the absolute risk of developing skin cancer from routine gel manicures is low for the general, healthy population. Studies analyzing population data, such as the Surveillance, Epidemiology, and End-results Program (SEER), have shown little to no increase in the incidence of melanoma or non-melanoma skin cancer on the hands of young adults since the rise of gel manicures.
Despite the low overall risk, the debate continues within the dermatological community. Case reports from 2009 described two healthy women who developed non-melanoma skin cancer on their hands after years of regular use, prompting further investigation. More recently, a 2023 laboratory study demonstrated that radiation from UV nail lamps can cause DNA damage, genetic mutations, and cell death in human and mouse cells.
These in vitro laboratory findings do not conclusively prove an increased cancer risk in living humans, as the exposure conditions were more intense and prolonged than a typical manicure session. The overall conclusion remains that while UV exposure is a known risk factor for skin cancer, the total dose accumulated during standard salon use is likely insufficient to cause significant concern for most individuals. Experts agree that the current lack of definitive long-term human studies warrants prudence and protective measures, especially for those with a high-risk history.
Recommended Safety and Protective Measures
Individuals who continue receiving gel manicures can take several actionable steps to mitigate the risks associated with UV exposure and chemical sensitization.
- Wear UV-protective, opaque fingerless gloves that cover the back of the hands and fingers, shielding the skin while leaving the nail plate exposed.
- Apply a broad-spectrum, water-resistant sunscreen (SPF 30 or higher) to the hands and fingers 15 to 20 minutes before the appointment to provide a chemical shield against UVA light.
- Ensure the nail technician is meticulous in application, preventing uncured gel polish from touching the skin, cuticles, or surrounding tissue to avoid chemical sensitization.
- Take “polish holidays” by keeping the nails bare for a week or two between applications to allow the nail plate to recover and check for abnormalities.
- When removing polish, only the nail plate should be soaked in acetone, typically by wrapping acetone-soaked cotton balls with aluminum foil around the fingertip. This practice minimizes the drying effect of acetone on the surrounding skin.

