House spiders possess the biological ability to bite, but such events are extremely uncommon, and the vast majority of bites that do occur are medically insignificant. These arachnids are not aggressive toward humans; their defense mechanisms are designed for subduing much smaller insect prey. Understanding the true nature of these interactions can significantly reduce anxiety about the spiders found inside a home.
Why Bites Are Rare and Misidentified
Spiders use venom to paralyze or kill insect prey, not to attack large threats like humans. A house spider will only bite defensively when it perceives immediate danger, such as being trapped or accidentally crushed against the skin. Most of the common species found indoors have fangs too small or weak to effectively penetrate human skin. Even if a fang pierces the skin, the amount of venom injected is often negligible and not intended to affect a large mammal.
The primary reason spider bites are reported frequently is due to widespread misidentification of skin lesions. Many dermatological conditions, including bacterial infections like Methicillin-resistant Staphylococcus aureus (MRSA) or irritations from fleas, mosquitoes, or hives, mimic the appearance of a mild spider bite. Studies have shown that unless a person actually witnessed the spider biting them, the cause of an unexplained sore or bump is far more likely to be an infection or another type of insect. Blaming a spider for any mysterious skin reaction often delays the correct diagnosis and treatment.
Common House Spiders and Their Bite Profiles
The most frequently encountered domestic species pose virtually no risk to human health. The Cellar Spider (Pholcus phalangioides), often mistaken for a daddy long-legs, is a delicate arachnid with small fangs. These spiders are gentle and rarely bite humans, and the circulating rumors about their potent venom are biologically unfounded. Their presence is actually beneficial as they consume other pests, including more problematic spiders.
The Common House Spider (Parasteatoda tepidariorum) creates the classic, messy webs seen in corners of basements and garages. While this species possesses venom, its fangs are usually too small to pierce the skin, and the venom is not medically significant. If a bite occurs, it typically results in only a localized, minor irritation similar to a pinprick or mosquito bite. The Jumping Spider (family Salticidae), recognized by its large front eyes and jerky movements, has a bite reaction comparable to a mild bee or wasp sting.
Sac Spiders (Cheiracanthium species) are sometimes found indoors and are one of the few common house spiders known to bite defensively. Although the bite can be more painful initially, similar to a scratch, the venom is not toxic or harmful to humans. Any reaction typically involves localized pain or redness and resolves completely within about 24 hours. The minimal impact of these common house species contrasts sharply with the few medically significant spiders, which are rarely found inside homes.
Managing a Suspected Spider Bite
If a small, unexplained bump appears and a spider bite is suspected, immediate first aid focuses on symptom relief and preventing secondary infection. The bite area should be gently cleaned with mild soap and water to keep the wound site sterile. Applying a cool compress or an ice pack wrapped in a cloth for 15-minute intervals helps reduce localized swelling and pain.
Over-the-counter medication can manage discomfort; an antihistamine may alleviate itching, and a pain reliever can help with soreness. Monitor the site for any signs that the irritation is worsening. Medical attention is necessary if a person develops signs of a severe allergic reaction, such as difficulty breathing, facial swelling, or widespread rash. A doctor should also be consulted if the bite area shows signs of infection like spreading redness, warmth, discharge, fever, or severe muscle pain.

