Does a UTI Affect Sperm and Fertility?

A urinary tract infection (UTI) develops when bacteria enter the urinary system, typically the urethra, and multiply in the bladder. Although UTIs are more common in women, they occur in men and raise concerns about reproductive health. The bacteria causing a UTI have the potential to migrate beyond the urinary tract. This migration raises the question of whether this common infection can impact the health and quality of a man’s sperm.

Understanding Male UTIs and the Reproductive Connection

A male UTI begins in the lower urinary system, involving the urethra or bladder. The male genitourinary tract connects the urinary and reproductive systems, as the urethra serves as the pathway for both urine and semen. This shared channel provides a direct route for infectious agents to spread. The infection can ascend into adjacent structures involved in sperm processing, such as the prostate gland and the epididymis. When the infection spreads, the resulting inflammation interferes with the environment necessary for healthy sperm, transforming a localized urinary problem into a reproductive health issue.

How Infection Directly Impacts Sperm Health

When an infection reaches the male reproductive tract, the body launches an immune response that can unintentionally harm sperm cells. This defense involves flooding the area with white blood cells (leukocytes) to fight the bacteria, a condition known as pyospermia when present in semen. These white blood cells release reactive oxygen species (ROS) to destroy pathogens. This oxidative stress damages delicate sperm membranes and can fragment the sperm’s DNA. Semen analysis reveals this damage as a reduction in sperm count, decreased motility (asthenozoospermia), and altered shape (teratozoospermia).

Related Infections That Pose Greater Fertility Risks

While a simple UTI temporarily affects sperm quality, greater fertility risks arise when the infection progresses into other reproductive organs. The most concerning related condition is epididymitis, which is inflammation of the epididymis. Infection spreading to the prostate gland causes prostatitis, altering the composition of the seminal fluid. The inflammation and swelling associated with these conditions can lead to scarring within the reproductive tract, potentially obstructing the ducts that transport sperm. This obstruction can cause obstructive azoospermia, meaning no sperm are present in the ejaculate.

Treatment, Recovery, and Timeline for Sperm Health

The standard treatment for an acute bacterial infection of the genitourinary tract involves a course of antibiotics. Once the infection is cleared and inflammation subsides, the temporary negative effects on sperm quality often resolve. Treatment may also include anti-inflammatory drugs to mitigate damage caused by the immune response. Sperm damage related to infection is frequently reversible because the body constantly produces new sperm cells. The complete cycle of sperm production, known as spermatogenesis, takes approximately two to three months. Specialists recommend waiting this period after completing antibiotic therapy before performing a follow-up semen analysis. This waiting time allows the reproductive system to produce a new batch of healthy sperm, providing an accurate picture of long-term fertility potential.