Does Hydrogen Peroxide Help Canker Sores?

Canker sores (aphthous ulcers) are common, painful, non-contagious mouth ulcers. These lesions are typically small, round, or oval sores inside the mouth, often appearing on the inner cheeks, lips, or tongue. They feature a distinctive white or yellowish center surrounded by a bright red, inflamed border. While most canker sores are minor and heal naturally, their discomfort can interfere with eating and speaking, leading many to seek quick relief through household remedies like hydrogen peroxide.

Hydrogen Peroxide: Mechanism and Effectiveness

Hydrogen peroxide (HP) is widely available as an antiseptic and is often considered for cleaning canker sores. When this chemical compound contacts mouth tissue, it reacts with the enzyme catalase. This reaction breaks down the hydrogen peroxide, releasing oxygen and creating the familiar foaming action. This bubbling process serves as a mechanical debriding agent, helping to lift and remove dead tissue, debris, and mucus from the ulcer surface. By cleaning the sore, HP helps reduce the bacterial load, which is a benefit for preventing secondary infection. Although canker sores are not caused by bacteria, keeping the open wound clean is important for the healing process. Scientific evidence that HP actively speeds up the healing time of the ulcer itself is limited; its primary function is to maintain a clean environment for natural healing.

Guidelines for Safe Oral Application

Using hydrogen peroxide for oral care requires careful dilution to prevent irritation or damage to the oral mucosa. The standard over-the-counter solution is 3% hydrogen peroxide, which is too concentrated for direct application. To create a safe oral rinse, mix equal parts of the 3% solution with water, yielding a final concentration of 1.5%. This diluted solution can be applied directly to the sore using a cotton swab or used as a brief mouth rinse. If rinsing, hold the solution in your mouth for about 60 seconds before spitting it out completely. Perform this treatment sparingly, typically three to four times a day at most, as overuse can cause tissue irritation. Never swallow the hydrogen peroxide solution, as ingestion can lead to stomach upset and is toxic in higher concentrations.

Non-Peroxide Treatments for Canker Sores

A variety of other treatments are available for managing the pain and promoting the healing of canker sores. Simple home remedies include rinsing with warm water and salt, which can soothe the irritated tissue. Baking soda rinses are also popular, as the alkaline nature of baking soda may help neutralize acids in the mouth, reducing irritation and promoting a better healing environment. Over-the-counter options often focus on pain relief and creating a protective barrier over the sore. Topical anesthetics, such as gels or liquids containing benzocaine or lidocaine, numb the area for temporary comfort during eating and drinking. Barrier pastes, like those containing carboxymethylcellulose, adhere to the sore to protect it from friction and irritation. For more severe or persistent cases, a doctor or dentist may prescribe medicated mouth rinses containing steroids, such as dexamethasone, or a specialized antibiotic mouthwash to reduce inflammation and pain.

Identifying When to Seek Medical Care

While most canker sores are minor and resolve on their own within one to two weeks, certain symptoms warrant a visit to a healthcare professional. You should seek medical attention if a sore is unusually large or if it begins to spread to the outer lips. Sores that persist for longer than two weeks without showing signs of healing may also indicate a need for professional diagnosis. Frequent, recurring outbreaks, where new sores appear before old ones have healed, should also be evaluated. Additionally, if the canker sore is accompanied by systemic symptoms, such as an unexplained high fever, difficulty swallowing, or a persistent feeling of illness, a medical assessment is necessary. These signs may suggest an underlying health condition that requires specific treatment beyond simple home care.