Does Low Testosterone Cause High Blood Pressure?

Men with low testosterone are more likely to have high blood pressure, and the pattern holds across the whole range of levels, not just at the extremes. A link isn’t a cause, though, and much of the overlap comes from a shared driver rather than one problem creating the other. In women the story flips: higher testosterone, not lower, goes with higher pressure. Whether raising testosterone would help your blood pressure depends a lot on why your levels are low to begin with.

How Strong the Link Is in Men

In a group of over 1,100 men aged 30 to 79, those with high blood pressure had lower testosterone than those without it.1PubMed. Blood pressure and endogenous testosterone in men: an inverse relationship Average blood pressure also fell a little with each step up in testosterone, across the whole range.2PubMed. Blood pressure and endogenous testosterone in men: an inverse relationship In middle-aged and older men, those in the top third of testosterone had about 16% lower odds of having hypertension than those in the bottom third.3PubMed Central. Association of Serum Testosterone and Luteinizing Hormone With Blood Pressure and Risk of Cardiovascular Disease in Middle‐Aged and Elderly Men

Low levels also predict trouble down the road, but only slightly. Men starting with testosterone in the lowest quarter were about 19% more likely to develop hypertension later than men with higher levels.4PubMed. Inverse association between total testosterone concentrations, incident hypertension and blood pressure That is a relative figure, so it adds a little to whatever risk you already carry. Age, weight, salt intake and family history usually matter more. The link was weaker in men over 65 and in heavier men, and stronger in smokers and men with a family history of hypertension.5PubMed Central. Association of Serum Testosterone and Luteinizing Hormone With Blood Pressure and Risk of Cardiovascular Disease in Middle‐Aged and Elderly Men

Which number on your lab report matters is a separate question. Most testosterone in blood is held by a protein called SHBG (sex hormone-binding globulin), and only 0.5% to 3% floats free.6PubMed Central. Association of total testosterone, free testosterone, bioavailable testosterone, sex hormone–binding globulin, and hypertension Total testosterone therefore doesn’t always show how much hormone your body can actually use, and free testosterone can be a better guide.7PubMed Central. Association of total testosterone, free testosterone, bioavailable testosterone, sex hormone–binding globulin, and hypertension But some common free-testosterone blood tests are less reliable, and earlier links between low free testosterone and hypertension may partly reflect the test.8Clinical Chemistry. The analog free testosterone assay: are the results in men clinically useful? If your result is borderline, ask whether free testosterone was calculated or measured by a reliable method.

One blood test can also mislead. Testosterone is highest in the morning, so tests are usually drawn early. Illness or poor sleep the week before can pull a reading down.

That is why diagnosis usually requires two separate morning draws that both come back low. It also generally requires symptoms such as low sex drive, erectile problems, fatigue or loss of muscle, not just a number on paper. Some men have a low number and feel fine, while others have symptoms with a number in the normal range.

If you have a confirmed low result, have your blood pressure checked at routine visits, since the two often appear together. If you have high blood pressure and symptoms like low sex drive or fatigue, you can ask whether testosterone is worth testing rather than assuming your blood pressure medicine is to blame. Some of those drugs can contribute to erectile trouble, so if you notice sexual symptoms after starting one, mention it instead of stopping the drug on your own.

Why Belly Fat Muddies the Cause

Fat packed around the abdominal organs may be the common factor behind both low testosterone and heart disease.9The Aging Male. Visceral obesity, androgens and the risks of cardiovascular disease and diabetes mellitus High insulin levels, common with this fat, lower the protein that holds testosterone in the blood, and so lower circulating testosterone.10The Aging Male. Visceral obesity, androgens and the risks of cardiovascular disease and diabetes mellitus Fat cells also release an appetite hormone, and high levels of it suppress testosterone.11The Aging Male. Visceral obesity, androgens and the risks of cardiovascular disease and diabetes mellitus

This fat matters more than the number on the scale. Fat around the organs is more harmful than fat under the skin, and a growing waist can signal it even when your weight changes little. Measuring around the navel is a simple home check.

Weight doesn’t explain everything. After accounting for age and body weight, the link between low testosterone and higher blood pressure shrank but didn’t disappear.12PubMed. Blood pressure and endogenous testosterone in men: an inverse relationship

The two problems also feed each other. Low testosterone makes it easier to gain belly fat and harder to keep muscle, and more belly fat then lowers testosterone further. It is hard to say which problem came first in any one man.

Losing weight can move both numbers. In overweight and obese men, a lifestyle program raised testosterone and lowered blood pressure near the heart.13PubMed. Lifestyle modification increases serum testosterone level and decrease central blood pressure in overweight and obese men The more testosterone rose, the more that blood pressure fell.14PubMed. Lifestyle modification increases serum testosterone level and decrease central blood pressure in overweight and obese men

Programs like this typically involve regular aerobic activity plus some strength training most days. Cutting refined carbs and sugary drinks helps lower insulin. Better sleep supports testosterone, since much of it is made overnight. Changes usually show over months, not weeks.

Other things can lower testosterone and raise pressure too. Sleep apnea, where breathing repeatedly stops during sleep, is common in heavier men and is linked to both. Heavy drinking can do the same. If you have loud snoring, gasping at night or daytime sleepiness, ask about a sleep test, because treating apnea may help both numbers.

What Low Testosterone Does to Blood Vessels

Men with lower testosterone tend to have artery linings that relax less well when blood flow increases.15PubMed. Association of testosterone levels with endothelial function in men: results from a population-based study Low testosterone may reduce nitric oxide, the gas that signals vessels to widen.16PubMed. Testosterone Deficiency and Endothelial Dysfunction: Nitric Oxide, Asymmetric Dimethylarginine, and Endothelial Progenitor Cells Older men with low testosterone also had higher blood levels of a chemical that tightens vessels than men with normal levels.17PubMed Central. Endothelial dysfunction in middle-aged and older men with low testosterone is associated with elevated circulating endothelin-1

The lining coats every blood vessel and acts like a control panel that tells the vessel when to widen or tighten. When it works poorly, vessels stay tighter than they should, and that raises the pressure the heart pumps against. This is a plausible way low testosterone could raise blood pressure, but the studies show a link, not proof of cause.

Arteries also get stiffer. In men under 60, low testosterone went with stiffness in the main artery that looked about 10 years older than their age.18PubMed. Testosterone deficiency: a determinant of aortic stiffness in men In men whose pressure was already high, low testosterone added to the stiffening.19PubMed. Testosterone deficiency: a determinant of aortic stiffness in men

Stiff arteries can’t stretch to absorb each heartbeat. That pushes the top (systolic) number up most, which is why systolic pressure tends to climb with age.

Testosterone can also relax vessels directly. In animal arteries, it relaxes the muscle in vessel walls.20PubMed. Testosterone relaxes coronary arteries by opening the large-conductance, calcium-activated potassium channel But in young men, blocking the conversion of testosterone into estrogen made vessels relax less well.21PubMed Central. Endogenous estrogens influence endothelial function in young men So some of testosterone’s vessel benefit in men seems to work through the estrogen the body makes from it. How much converts differs from man to man, so simply taking more testosterone doesn’t guarantee better vessels.

Will Testosterone Therapy Lower Your Blood Pressure

Some men see a drop. In men with clearly low testosterone, long-acting testosterone injections were linked to lower blood pressure, whether or not they took blood pressure medicine.22PubMed Central. Testosterone Replacement Therapy: Effects on Blood Pressure in Hypogonadal Men The drop was larger in men also taking blood pressure medicine.23PubMed Central. Testosterone Replacement Therapy: Effects on Blood Pressure in Hypogonadal Men

Others see a small rise. Over a year, average top-number blood pressure rose about 2 points on a testosterone pill and about 3 points on a gel.24Androgens: Clinical Research and Therapeutics. Effects of Oral Testosterone Undecanoate (Kyzatrex) Versus Testosterone Gel (Androgel) on Long-Term (to 12 Months) Blood Pressure Levels Heart rate rose about 3 to 4 beats per minute.25Androgens: Clinical Research and Therapeutics. Effects of Oral Testosterone Undecanoate (Kyzatrex) Versus Testosterone Gel (Androgel) on Long-Term (to 12 Months) Blood Pressure Levels In men without hypertension, the pill raised pressure less than the gel, and more men on gel saw jumps of 5 or 10 points.26Androgens: Clinical Research and Therapeutics. Effects of Oral Testosterone Undecanoate (Kyzatrex) Versus Testosterone Gel (Androgel) on Long-Term (to 12 Months) Blood Pressure Levels The studies differ in who they enrolled, what form of testosterone they used and how long they lasted, so no single result tells an individual man which way his own pressure will go.

A rise of two or three points in the top number is small for one person, but it matters more if your pressure is already near the treatment threshold. Averages hide individuals, and some men had much larger jumps. A faster heart rate of three or four beats a minute is usually minor, but worth noticing if you also have palpitations or heart disease.

Thicker blood can drive the rise. Testosterone raises hematocrit, the share of your blood made of red cells, by about 3 points on average.27PubMed. Effects of a Novel Oral Testosterone Undecanoate on Ambulatory Blood Pressure in Hypogonadal Men Men with the biggest hematocrit rises saw top-number pressure go up about 8 points over the day, versus about 2 to 3 points in others.28PubMed. Effects of a Novel Oral Testosterone Undecanoate on Ambulatory Blood Pressure in Hypogonadal Men Regular blood counts while on treatment help catch the men most likely to see a rise. If the count climbs too high, a doctor may lower the dose or change the form, so don’t skip scheduled blood tests.

Take a home blood pressure reading before starting so you have a baseline. Recheck in the first few months at the same time of day, and bring the readings to follow-up visits along with your blood work.

Some men shouldn’t expect therapy to fix their blood pressure. Men with borderline-low levels from weight gain may get little benefit. Therapy is meant for confirmed low levels with symptoms, and blood pressure medicine stays the main treatment for hypertension.

Does the Type of Testosterone Matter

Men starting testosterone injections had about 26% more heart attacks and strokes than men starting gels.29PubMed Central. Comparative safety of testosterone dosage forms Their risk of hospital stays and death was higher too.30PubMed Central. Comparative safety of testosterone dosage forms Patches showed no clear extra risk compared with gels.31PubMed Central. Comparative safety of testosterone dosage forms

This isn’t a final verdict. The study compared men who started different forms in real-world care, not men randomly assigned to them, so other differences between the groups could play a role. Men given injections may differ in health, income or reasons for treatment, so the result is a reason for caution, not proof that injections cause heart attacks.

Steady levels may be part of the story. Short-acting injections cause big swings in testosterone, with ups and downs in mood and energy.32PubMed Central. Testosterone in men with hypogonadism and transgender males: a systematic review comparing three different preparations Long-acting injections give more stable levels, while gels need daily use that is easy to skip and can transfer to partners and children by skin contact.33PubMed Central. Testosterone in men with hypogonadism and transgender males: a systematic review comparing three different preparations Those swings are one idea for why injection forms may differ in heart effects, though that explanation hasn’t been proved.

When you talk to your doctor about form, ask how often you’d dose and how steady your levels stay. Mention any heart disease or high blood pressure history, and ask how blood counts and pressure will be monitored.

Steroid Use and Very High Testosterone

Among bodybuilders using anabolic steroids, about 70% had high blood pressure, versus 35% of non-users.34PubMed Central. Cardiovascular manifestations of anabolic steroids in association with demographic variables in body building athletes The longer the use, the higher the pressure.35PubMed Central. Cardiovascular manifestations of anabolic steroids in association with demographic variables in body building athletes Steroids make the kidneys hold onto salt and water,36PubMed Central. Cardiac and Metabolic Effects of Anabolic-Androgenic Steroid Abuse on Lipids, Blood Pressure, Left Ventricular Dimensions, and Rhythm and pressure can stay raised for 5 to 12 months after stopping.37PubMed Central. Cardiac and Metabolic Effects of Anabolic-Androgenic Steroid Abuse on Lipids, Blood Pressure, Left Ventricular Dimensions, and Rhythm

This differs from medical therapy, which aims for normal levels, not muscle-building doses. Bodybuilders often take several steroids at once at doses many times what the body makes, so pressure effects can be much larger. Many users also take stimulants or high-dose supplements, which add strain. Studies of users compare groups of people, so they show an association and can’t pin the full effect on steroids alone. Anyone who has used steroids should get pressure checked for months afterward.

Why It Works Differently in Women

In women, higher testosterone was linked to higher blood pressure, most strongly after menopause.38PubMed. Positive association between testosterone, blood pressure, and hypertension in women: longitudinal findings from the Study of Health in Pomerania Women with the lowest testosterone had about 21% lower risk of hypertension.39PubMed. Positive association between testosterone, blood pressure, and hypertension in women: longitudinal findings from the Study of Health in Pomerania In young women with polycystic ovary syndrome (PCOS), high testosterone nearly quadrupled the odds of raised blood pressure, regardless of weight.40PubMed. Relationship between androgen levels and blood pressure in young women with polycystic ovary syndrome

Women normally have much lower testosterone than men, so a higher level in a woman falls outside her usual range and can act differently. It often goes with metabolic changes such as more belly fat and insulin resistance, which raise pressure.

PCOS is a common hormone condition in which the ovaries make more androgens, the male-type hormones, including testosterone. It is often accompanied by irregular periods, acne, extra hair growth and insulin resistance.

Menopause shifts the balance, because estrogen falls steeply and the ratio of estrogen to testosterone changes. That may help explain why the link was strongest after menopause. Blood pressure also tends to rise then for several reasons, so hormones are only one piece.

For women, this means regular blood pressure checks if you have PCOS. Testosterone products for women carry their own blood pressure considerations, and trans men starting testosterone should have pressure monitored too.