A fever is a temporary elevation of the body’s temperature, generally considered to be 100.4°F (38°C) or higher. This rise in temperature is a regulated part of the body’s defense mechanism against infection or disease. When the immune system detects an invading pathogen, such as a virus or bacteria, it triggers the hypothalamus to reset the body temperature to a higher level. This elevated temperature inhibits the growth of many pathogens and enhances the activity of immune cells, helping the body fight off the illness more effectively.
The Typical Duration of a Fever
For most healthy adults and older children, a fever from a common viral illness, such as a cold or the flu, is expected to be short-lived. The typical duration for this acute fever is generally between 24 and 72 hours, or up to three full days. During this time, the immune response is vigorous, and the body successfully lowers its temperature as the infection comes under control.
A fever lasting beyond this period, such as four or five days, is described as persistent. While many viral fevers peak and decline quickly, they often fluctuate throughout the day before fully resolving. The overall duration is a primary indicator of whether the underlying cause is a common, self-limiting issue or something requiring further investigation.
Fevers caused by a virus resolve once the body has cleared the infection, but the total time varies depending on the specific pathogen. For instance, the fever phase of influenza often lasts around three to four days before subsiding.
Factors Determining How Long a Fever Persists
The actual length of a fever is influenced by several biological and environmental factors. The distinction between a viral and a bacterial infection is the most significant variable in fever duration. Fevers from viral infections typically run a predictable, shorter course because the immune system can clear the virus on its own in a matter of days.
In contrast, fevers caused by a bacterial infection, such as strep throat or a urinary tract infection, may persist longer. These fevers often do not resolve until a specific treatment, like antibiotics, is administered. The strength of an individual’s immune response also plays a role, as a robust activation of immune cells can shorten the symptomatic phase of an illness.
People with weakened immune systems may experience longer or recurring fevers because their body takes more time to mount an effective defense. Management factors like hydration and rest can also indirectly affect how long a fever lasts by supporting the immune system’s function. Dehydration, a common risk with fever, can place additional stress on the body and hinder the recovery process.
Critical Timeframes for Seeking Medical Care
The duration of a fever signals when to seek professional medical evaluation. For adults and older children, medical consultation is advised if a fever of 100.4°F (38°C) or higher persists for longer than 72 hours, or three days. A fever that reaches 103°F (39.4°C) or higher warrants a call to a healthcare provider, regardless of how long it has lasted.
The rules for infants are stricter due to their limited ability to fight off serious infections and the risk of rapid progression of illness. Any infant younger than three months old who has a temperature of 100.4°F (38°C) or higher, taken rectally, needs immediate medical attention. For babies between three and six months old, a fever over 102°F (38.9°C) or a lower temperature accompanied by unusual irritability or sluggishness should prompt a call to the doctor.
Regardless of age or duration, certain accompanying symptoms require urgent care. These warning signs indicate a potentially serious condition:
- Severe headache
- Unusual rash
- Mental confusion
- Difficulty breathing
- Stiff neck
- Persistent vomiting
- Seizures

