Treating an inflamed cyst often involves an intralesional corticosteroid injection, commonly known as a cortisone shot. This procedure is a targeted medical intervention used for benign, inflamed lesions like cystic acne, certain epidermoid cysts, or minor ganglion cysts. The injection delivers anti-inflammatory medication directly into the lesion to reduce its size and associated symptoms. Setting realistic expectations is important, as the goal is a rapid resolution of swelling and discomfort.
How Cortisone Shots Treat Cysts
A cortisone shot does not remove the cyst wall or its contents, but instead targets the inflammation that makes the lesion noticeable and painful. The substance injected is a synthetic corticosteroid, often triamcinolone, which is a strong anti-inflammatory agent. When administered directly into the cyst, the steroid suppresses the localized immune response that causes the swelling, redness, and heat.
The injected steroid also helps break down the fibrous tissue that surrounds the lesion, particularly in mature cysts. By reducing the swelling and dissolving some of the internal structure, the overall volume of the cyst decreases. This localized action minimizes systemic side effects compared to oral steroids. The primary objective is to quickly relieve acute symptoms and shrink the noticeable lump.
The Typical Timeline for Cyst Shrinkage
Patients experience an initial response quickly, often noticing a reduction in pain and tenderness within 24 to 48 hours. This early relief is due to the anti-inflammatory action of the corticosteroid calming the inflamed tissue. Redness and swelling that characterize an irritated cyst also begin to subside during this first one to two days.
Visible shrinkage of the physical lump usually starts within three to seven days following the procedure. During this period, the localized effects of the steroid cause the cyst to visibly flatten as inflammation resolves. The maximum cosmetic effect, where the cyst has reached its full reduction, is generally achieved within one to two weeks of the injection.
Why Results May Vary After Injection
The speed and degree of cyst resolution depend on several factors that influence the body’s response to the treatment. The starting size and depth of the cyst play a large role, as a deep, large, or highly fibrous cyst takes longer to break down and flatten than a small, superficial nodule. The specific type of lesion is also a factor; for example, a cystic acne lesion may respond differently than a deep epidermoid cyst.
The dosage and concentration of the steroid used, such as triamcinolone acetonide, are selected by the healthcare provider to optimize results. A particularly large cyst or one with a dense internal structure may require a higher concentration or a larger volume, which affects the timeline. The patient’s individual metabolic response to corticosteroids also impacts how quickly the medication is processed and how effectively inflammation is reduced. If a cyst does not fully resolve after two weeks, a second, follow-up injection may be needed to achieve complete flattening.