About 48.4 million Americans ages 12 and older had a substance use disorder in 2023, representing 16.8% of that population. That figure, from the federal government’s annual National Survey on Drug Use and Health, includes addiction to both legal and illegal substances, with alcohol accounting for the largest share.
What “Substance Use Disorder” Actually Means
The clinical term for addiction is substance use disorder, or SUD. It’s diagnosed on a spectrum based on how many warning signs a person shows out of a possible 11. Someone with two or three signs is considered to have a mild disorder, four or five is moderate, and six or more is severe. Those signs include things like using more than intended, unsuccessful attempts to cut back, spending a large amount of time obtaining or recovering from a substance, cravings, and continuing to use despite clear harm to relationships, work, or health. Tolerance (needing more to get the same effect) and withdrawal symptoms also count.
This means the 48.4 million figure isn’t limited to people with the most severe forms of addiction. It captures a wide range, from someone who repeatedly tries and fails to control their drinking to someone physically dependent on fentanyl.
Alcohol Is the Biggest Piece
More than 29 million Americans ages 12 and older had an alcohol use disorder as of 2022, making it by far the most common substance use disorder in the country. That’s roughly 60% of all substance use disorder cases. Young adults ages 18 to 25 are particularly affected: their rates of binge drinking (34.9%) and heavy drinking (9.0%) are substantially higher than those of adults 26 and older (25.1% and 6.2%, respectively), even though both groups report similar overall rates of alcohol use.
Cannabis Addiction Is Rising Fast
About 19 million people ages 12 and older met the criteria for cannabis use disorder in 2022. That number has climbed alongside legalization and increasing daily use. Roughly one in five people who use cannabis develop a use disorder, which can involve difficulty cutting back, withdrawal symptoms like irritability and sleep problems, and continued use despite negative effects on daily life. The growing prevalence of high-potency products likely plays a role in this trend.
Opioids, Meth, and Cocaine
Stimulants and opioids account for smaller but deeply consequential shares of the total. In 2023, about 1.8 million people had a methamphetamine use disorder and 1.3 million had a cocaine use disorder. Methamphetamine addiction has been climbing particularly fast among adults 26 and older, with a 33% increase between 2016 and 2018 alone.
Opioid use disorders, while smaller in raw numbers than alcohol or cannabis, carry the highest mortality risk. Adults 26 and older account for 79% of all opioid use disorders in the country.
The Treatment Gap
Only 24% of people who needed substance use treatment in 2022 actually received it. That means more than 36 million Americans with a substance use disorder went without care in a single year. The reasons are layered: limited access to treatment programs, a shortage of providers, cost, stigma, and the simple fact that many people with a substance use disorder don’t recognize or accept that they need help. Screening in primary care settings remains inconsistent, so many cases go unidentified even when someone is seeing a doctor regularly.
Overdose Deaths Are Declining
After years of relentless increases, drug overdose deaths dropped significantly. In 2024, 79,384 people died from drug overdoses, down from higher totals in prior years. The biggest decline came from synthetic opioids like fentanyl, where death rates fell 35.6% between 2023 and 2024. Heroin-related deaths dropped 33.3%, cocaine deaths fell 26.7%, and deaths involving stimulants like methamphetamine decreased 19.8%.
These declines likely reflect a combination of wider availability of the overdose-reversal medication naloxone, expanded access to medications that treat opioid addiction, and public health campaigns targeting fentanyl awareness. Still, nearly 80,000 deaths in a single year remains an extraordinary toll, roughly equivalent to a mid-sized city disappearing every year.
Age Groups Affected Differently
Adolescents (ages 12 to 17) and young adults (18 to 25) have actually seen progress in reducing substance use disorder rates in recent years. The more concerning trend is among adults 26 and older, where rates have stayed flat or increased. This older group represents the vast majority of opioid and methamphetamine use disorders and is less likely to age out of problematic use the way younger people sometimes do.
The pattern challenges a common assumption that addiction is primarily a young person’s problem. While younger people are more likely to experiment and engage in risky patterns of use, the chronic, entrenched forms of addiction that drive overdose deaths and long-term health consequences are concentrated in adults well past their twenties.

