A sneeze, or sternutation, is a powerful, involuntary reflex that protects the body’s respiratory system. This rapid expulsion of air has generated persistent myths, often due to the sheer force involved. One widespread misconception is the idea that the physical shock of a sneeze causes a measurable loss of brain cells. This article examines the sneeze reflex, its physical mechanisms, and the neurological control that manages this event.
The Truth About Brain Cell Loss
The definitive answer to how many brain cells you lose when you sneeze is zero. The notion that neurons are destroyed by a sneeze is a myth stemming from a misunderstanding of the minor, temporary pressure changes that occur during the reflex. The brain is well-protected, encased within the hard, bony structure of the skull and cushioned by cerebrospinal fluid.
The minimal increase in intracranial pressure from a sneeze is too brief and too slight to cause any neuronal damage. The pressure spike is comparable to the pressure changes that occur during a strong cough or a hearty laugh. Unlike conditions like a stroke, which involve sustained, severe pressure on the brain, a sneeze is a benign, external respiratory event, not an internal neurological hazard.
The Physiology of a Sneeze
The function of a sneeze is to forcibly clear irritants, like dust or pollen, from the nasal passages and upper respiratory tract. This protective action is preceded by a deep inhalation that draws a large volume of air into the lungs. The body then begins a rapid and coordinated sequence of muscle contractions involving the chest, abdomen, diaphragm, and throat.
This forceful contraction builds significant pressure within the chest cavity, which is then suddenly released. The air is expelled through the nose and mouth in an explosive burst, with airflow speeds that can reach nearly 100 kilometers per hour. Stifling a sneeze, however, can potentially redirect this pressure, which has been associated with rare but documented cases of injury to the ears, sinuses, or even the throat.
How the Brain Manages the Reflex
The sneeze is a complex, involuntary action controlled by the central nervous system. The entire process begins when specialized sensory nerve endings in the nasal lining, known as pruriceptors, detect an irritant. This stimulus signal is then transmitted to the brainstem via the trigeminal nerve.
The brainstem, specifically the medulla oblongata, contains the “sneezing center,” which acts as the control center for the reflex. This region coordinates the subsequent motor signals sent to the various muscle groups necessary for the physical expulsion of air. The brain initiates the powerful reflex while ensuring that other vital functions, such as breathing and heart rate, remain stable throughout the brief, temporary interruption.

