Approximately 5.4 million people in the United States live with some form of paralysis, a figure that includes partial and complete loss of movement from any cause. Globally, spinal cord injury alone accounts for over 15 million people living with disability, and that number doesn’t capture the millions more paralyzed by stroke, multiple sclerosis, or cerebral palsy.
Paralysis in the United States
The most comprehensive U.S. estimate comes from a 2013 national survey published in the American Journal of Public Health, which found nearly 5.4 million Americans living with paralysis. That’s roughly 1 in 50 people. The number encompasses everyone from someone with partial weakness on one side of their body after a stroke to someone with complete loss of movement and sensation below the neck after a spinal cord injury.
Stroke is the single largest contributor to paralysis in the U.S. About 40% of stroke survivors experience moderate to severe impairments requiring ongoing care, and another 10% need long-term institutional support. Only about 10% recover almost completely. Because nearly 800,000 Americans have a stroke each year, the population of stroke survivors living with some degree of paralysis grows steadily.
Spinal Cord Injury by the Numbers
Between 255,000 and 390,000 Americans are currently living with a spinal cord injury. Around 18,000 new traumatic spinal cord injuries occur each year, a rate of about 54 per million people that has held relatively steady since the early 1990s. These figures exclude people who die at the scene of an accident.
Worldwide, roughly 15.4 million people were living with a spinal cord injury as of 2021, according to the World Health Organization. SCI accounted for over 4.5 million years of life lived with disability globally that year, reflecting the condition’s severity and the decades of care many survivors require.
Other Major Causes
Multiple sclerosis affects an estimated one million Americans, and mobility loss is one of its hallmark features. About 80% of people with MS will experience impaired mobility within 10 to 15 years of diagnosis. Surveys of working-age adults with MS have found that roughly 60% own at least one mobility aid, most commonly a manual wheelchair or a cane. Around half of all people living with MS need a wheelchair or walking aid some or all of the time.
Cerebral palsy is the most common motor disability in childhood. Among children with CP, about 33% have limited or no walking ability, roughly 8% walk with a handheld device, and 59% can walk independently. Another analysis found that 41% of children with CP were limited in their ability to crawl, walk, run, or play, and 31% used specialized equipment like walkers or wheelchairs.
The Financial Reality
Paralysis carries enormous costs, especially for spinal cord injuries. The lifetime price of care depends heavily on the severity of the injury and the age at which it occurs. For a 25-year-old with a high-level spinal cord injury affecting all four limbs, estimated lifetime healthcare costs exceed $4.7 million. For paraplegia at the same age, that figure is about $2.3 million. Even an incomplete injury with some preserved movement runs close to $1.6 million over a lifetime.
These numbers cover only direct medical expenses. Lost wages, benefits, and productivity add an average of roughly $72,000 per year on top of that. For someone injured young, the total economic impact can easily surpass $6 million.
For a 50-year-old, the lifetime costs are lower simply because of shorter life expectancy after injury, but they still range from about $1.1 million for an incomplete injury to $2.6 million for a high-level injury affecting all four limbs.
Why These Numbers Are Likely Undercounts
The 5.4 million figure for the U.S. is based on 2013 survey data, and no comparable national study has been conducted since. The aging population means more strokes each year. Survival rates for both stroke and spinal cord injury have improved, which means more people living longer with paralysis. The global figure of 15.4 million covers only spinal cord injuries, leaving out the tens of millions paralyzed by stroke, MS, cerebral palsy, traumatic brain injury, and other neurological conditions. A true global count of all people living with paralysis would be substantially higher, though no single estimate exists.

