Daxxify typically costs between $15 and $25 per unit, with most providers charging in the $15 to $20 range. That’s roughly 50% more per unit than Botox, which averages $10 to $15 per unit. But the per-unit price only tells part of the story, because Daxxify uses different unit counts and lasts significantly longer than its competitors.
What a Full Treatment Actually Costs
The FDA-approved dose for frown lines (the “elevens” between your eyebrows) is 40 units of Daxxify per session, split across five injection sites. At $15 to $20 per unit, that puts a single treatment session at roughly $600 to $800 for frown lines alone. Some providers charge toward the higher end of the per-unit range, pushing a session closer to $1,000.
For comparison, the same area treated with Botox uses about 20 units at $10 to $15 per unit, totaling $200 to $300 per session. Dysport treats frown lines with 50 to 60 units at $4 to $8 per unit, landing in the $200 to $480 range. So on a single-visit basis, Daxxify is the most expensive option.
Why the Unit Counts Differ
Daxxify units are not interchangeable with Botox units. A “unit” of each product reflects a different amount of active ingredient, so you can’t simply compare 40 units of Daxxify to 20 units of Botox and assume you’re getting twice as much. The products are formulated differently and dosed according to their own clinical trials. Daxxify’s 40-unit standard dose was specifically tested and approved at that level for frown lines.
If your provider treats additional areas like forehead lines or crow’s feet (which are off-label uses for Daxxify), the total unit count and cost will climb. Providers who use Daxxify for broader facial treatment typically use around 140 units over a six-month period.
The Annual Math Favors Daxxify
Where Daxxify closes the cost gap is longevity. Clinical results for frown lines last four to six months, and sometimes longer. Botox, Dysport, and Xeomin typically wear off in three to four months. That means most Botox patients need three treatments a year, while Daxxify patients need two.
When you run the annual numbers, the difference narrows considerably. Daxxify averages about $3,360 per year for two treatment sessions, while Botox runs roughly $2,730 per year across three sessions. That’s a difference of about $630 annually, or around $50 more per month, for the convenience of fewer office visits and longer-lasting results.
What Makes Daxxify More Expensive
Daxxify’s higher price reflects a different manufacturing approach. Traditional neurotoxins like Botox use human or animal proteins as stabilizing ingredients. Daxxify instead uses a proprietary peptide (a small chain of amino acids) that is entirely lab-made and vegan. This peptide is biologically active, meaning it doesn’t just stabilize the product but contributes to how it works in the muscle. According to the American Society of Plastic Surgeons, this peptide exchange technology is what gives Daxxify its extended duration compared to older formulations.
The result is a product with no human or animal-derived components, which appeals to some patients on its own. But the practical selling point is fewer appointments per year with comparable smoothing results.
How Prices Vary by Provider
Like all injectable treatments, Daxxify pricing is set by individual providers, not by the manufacturer. You’ll see meaningful price differences depending on geographic location, the injector’s experience level, and whether the practice is in a competitive urban market. A provider in New York City or Los Angeles may charge $20 to $25 per unit, while a practice in a smaller metro area might price closer to $15.
Some providers also structure pricing per treatment area rather than per unit, which can make direct comparison harder. If you’re quoted a flat fee for frown lines, divide by 40 to get your effective per-unit rate.
Discounts and Savings Programs
Revance, the company behind Daxxify, offers a $50 rebate for new patients through a prepaid e-gift card program. It’s a modest discount, but it’s worth claiming if you’re trying Daxxify for the first time. The current offer runs through early 2026.
Beyond manufacturer promotions, many practices offer loyalty pricing, package deals, or membership programs that reduce the per-unit cost for returning patients. If you’re planning to use Daxxify long-term, ask your provider whether they offer any bundled pricing, since committing to two sessions a year gives them predictable revenue and gives you leverage to negotiate.
Daxxify vs. Competitors at a Glance
- Daxxify: $15 to $25 per unit, 40 units per frown line treatment, results last 4 to 6+ months, roughly 2 treatments per year
- Botox: $10 to $15 per unit, 20 units per frown line treatment, results last 3 to 4 months, roughly 3 treatments per year
- Dysport: $4 to $8 per unit, 50 to 60 units per frown line treatment, results last 3 to 4 months, roughly 3 treatments per year
- Xeomin: $10 to $15 per unit, 20 units per frown line treatment, results last 3 to 4 months, roughly 3 treatments per year
The cheapest per-unit option is Dysport, but its higher unit requirements even out the session cost. Botox and Xeomin fall in a similar price range per treatment. Daxxify costs the most per session but requires the fewest sessions annually, making it the most convenient option for people who value fewer office visits and are comfortable paying a moderate annual premium for that benefit.