How to Do Acupressure for Stress, Nausea, and Pain

Acupressure is a self-care technique where you use your fingers to apply steady pressure to specific points on the body. It’s simple to learn, requires no equipment, and you can do it almost anywhere. The basic method involves pressing a point with your thumb or middle finger using small circular movements, holding firm pressure that feels strong but still comfortable, for about one to three minutes per point.

How Acupressure Works in Your Body

When you press on an acupressure point, you’re stimulating nerve-rich areas that trigger a chain of responses in your nervous system. The pressure prompts your brain to release natural pain-relieving chemicals, including endorphins and other opioid-like substances your body produces on its own. These are the same compounds responsible for “runner’s high” and the relief you feel after a good massage.

The effects go beyond pain relief. Stimulating these points can also dial down inflammation markers and influence how your nervous system regulates everything from digestion to mood. A meta-analysis of acupressure for osteoarthritis found that when people added acupressure to their existing treatment, they experienced significantly greater pain reduction than those using conventional treatment alone.

The Basic Technique

Use the pad of your thumb or middle finger, not your nail. Place it directly on the point you want to stimulate and press inward with steady, firm pressure. You’re aiming for a sensation that’s deep and noticeable, maybe slightly tender, but never sharp or painful. If it hurts, ease up.

Once you’ve found the right pressure, make slow circular motions while maintaining contact with the skin. Hold each point for one to three minutes. Breathe slowly and evenly while you press. You can work the same points twice a day, and most clinical protocols run for about four weeks to see lasting results.

A few practical tips: warm your hands first if they’re cold, since tense muscles respond better to warm touch. Sit or lie in a comfortable position so you can relax the area you’re working on. And don’t press on broken skin, bruises, varicose veins, or areas of swelling.

LI4: The Point on Your Hand

This is probably the most widely used acupressure point. It sits in the fleshy web between your thumb and index finger, right at the base where the bones of those two fingers meet on the back of your hand. To find it, squeeze your thumb against your index finger and look for the highest point of the muscle that bulges up. That’s LI4.

Press into this spot with the thumb of your opposite hand, angling slightly toward the index finger bone. You’ll likely feel a deep, achy sensation that confirms you’re in the right place. This point is traditionally used for headaches, toothaches, sore throats, shoulder tension, and sinus congestion. Research also shows stimulation here improves blood circulation in the hand, which is why it’s used for conditions involving poor peripheral circulation.

Work this point on both hands, one to three minutes per side.

P6: The Anti-Nausea Point

If you’ve ever worn a motion sickness wristband, it was targeting this point. P6 sits on the inside of your forearm, about three finger-widths below your wrist crease. Memorial Sloan Kettering Cancer Center recommends this method to find it: hold your hand up with your palm facing you, then place three fingers of your opposite hand across your wrist just below the crease. The point is right beneath your index finger, between the two tendons you can feel running down the center of your inner forearm.

Press your thumb between those two tendons and apply firm, steady pressure. This point is effective for nausea, vomiting, and motion sickness. It’s one of the most studied acupressure points and is commonly recommended to people undergoing chemotherapy or recovering from surgery.

LV3: The Stress Relief Point

This point is on the top of your foot, in the depression where the bones of your big toe and second toe converge. Slide your finger from the web between those two toes back toward your ankle until you feel a small hollow where the bones meet. That’s LV3.

Press down into this spot with your thumb. Brain imaging studies show that stimulating this point activates regions involved in emotional processing and pain perception, and that holding it longer intensifies the response. It’s one of the go-to points for stress, anxiety, irritability, and tension headaches. Many practitioners pair it with LI4 on the hand for a combination sometimes called the “four gates,” which addresses both physical pain and emotional tension.

ST36: The Energy and Immunity Point

This one’s on your lower leg. Start by finding the bottom edge of your kneecap. Move about four finger-widths straight down, then one finger-width toward the outside of your shinbone. You should land in a small muscle that flexes when you move your foot up and down. That’s ST36.

This point has the broadest range of studied effects of any acupressure point. Stimulating it influences inflammation levels throughout the body, supports immune cell function, and affects digestive activity. Research in animal models shows it can reduce key inflammatory markers while boosting anti-inflammatory ones. In traditional practice, it’s the primary point for fatigue, digestive issues, and general immune support. Press firmly with your thumb, using circular motions, for one to three minutes on each leg.

Combining Points for Common Issues

  • Headaches and tension: Start with LI4 on both hands, then add LV3 on both feet. This combination addresses pain while calming the nervous system.
  • Nausea: Focus on P6 on both wrists. Press for two to three minutes per side, repeating as needed.
  • Stress and anxiety: Use LV3 on both feet, followed by P6 on both wrists. Slow your breathing while you hold each point.
  • Low energy or digestive discomfort: Work ST36 on both legs. This is also a good daily maintenance point for overall wellness.
  • General pain relief: LI4 is usually the starting point for any kind of pain above the waist, including dental pain, sinus pressure, and neck stiffness.

You don’t need to hit every point in a single session. Pick two or three that match what you’re dealing with, and work through them in a sequence that feels natural. A full routine typically takes 10 to 15 minutes.

Safety Considerations

Acupressure is generally low-risk, but there are important exceptions. If you’re pregnant, avoid LI4 (the hand point) and several other points that can stimulate uterine contractions. Five points are traditionally considered off-limits during pregnancy because of their potential to induce labor: LI4 on the hand, SP6 on the inner ankle, BL60 on the outer ankle near the Achilles tendon, GB21 on the top of the shoulder, and CV3 on the lower abdomen. These points are powerful enough that practitioners sometimes use them deliberately to encourage labor at full term, which is exactly why they’re avoided earlier in pregnancy.

Beyond pregnancy, avoid pressing directly on tumors, inflamed joints, areas of infection, or recent surgical sites. People with bleeding disorders or those taking blood thinners should use lighter pressure. If pressing a point causes sharp or radiating pain rather than a dull, achy sensation, you’re either pressing too hard or slightly off the point. Adjust your position or reduce your pressure.