Meibomian glands are specialized sebaceous glands located along the rims of the upper and lower eyelids, responsible for producing meibum, the oily outer layer of the tear film. This oily secretion is essential because it prevents the watery layer of tears from evaporating too quickly, ensuring the eye remains lubricated and comfortable. When these glands become blocked or their secretions thicken, a condition known as Meibomian Gland Dysfunction (MGD) occurs, which is a leading cause of chronic dry eye disease. Expression is the process of physically clearing this blockage to restore the flow of meibum and improve tear quality.
Preparing the Glands for Effective Expression
Meibomian gland expression begins by softening the meibum, which often becomes thick or toothpaste-like due to MGD. Since thickened meibum has a higher melting point, applying heat is necessary to liquefy the solidified oil, allowing it to flow easily out of the gland ducts. Warm compresses are the standard at-home method, typically applied using a heated eye mask or a clean washcloth. The goal is a therapeutic temperature of 40°C to 42°C (104°F to 107.6°F) on the inner eyelid surface. The compress should be applied to closed eyelids for five to ten minutes, allowing heat to penetrate the tissue.
Self-Care Techniques for Gentle Expression
After applying heat, immediate gentle expression helps push the now-liquefied meibum out of the glands. This at-home step must be performed with clean hands to minimize the risk of introducing bacteria. The technique involves applying light, directed pressure to the eyelids to “milk” the glands toward the lid margin.
For the upper eyelid, a clean finger or cotton-tipped applicator is gently rolled or stroked downward, starting below the eyebrow and moving toward the lash line. This movement follows the vertical orientation of the glands within the eyelid tissue. On the lower eyelid, the same motion is performed in an upward direction, pushing the oil toward the lower lash line.
The pressure should be firm enough to squeeze the glands but gentle enough to avoid discomfort or pressing directly onto the eyeball. Completing this gentle massage across the entire width of both eyelids ensures all glands are addressed. Temporary blurred vision immediately following expression is a common sign that oils have been successfully released. Consistent, daily self-expression is often required, as MGD is a chronic condition causing meibum to re-thicken over time.
Professional In-Office Expression Methods
When at-home methods are insufficient for clearing severe blockages, eye care professionals perform specialized in-office expression procedures. These methods deliver a higher, more consistent therapeutic temperature and controlled pressure directly to the glands. The goal of professional intervention is a thorough, deep clearing of the glands that may be difficult to achieve manually.
Thermal Pulsation Devices
Devices utilizing thermal pulsation, such as LipiFlow, iLux, or TearCare, combine sustained heat with mechanical pressure. The LipiFlow system, for example, delivers controlled heat at 42.5°C to the inner eyelid while applying pulsatile pressure to the outer eyelid during a 12-minute cycle. This design allows heat to reach the glands effectively while protecting the sensitive cornea.
Manual Expression
Other professional methods involve the doctor manually expressing the glands using specialized instruments, such as MGE forceps or a Mastrota Meibomian Paddle, often after applying localized heat. These tools allow the practitioner to apply precise pressure to individual glands under magnification, targeting stubborn blockages. These procedures significantly increase the quality and volume of meibum secreted and are recommended for patients with moderate to severe MGD.
Long-Term Strategies for Gland Maintenance
Maintaining gland function requires an ongoing, preventative regimen following initial expression. Regular lid hygiene is a primary strategy for preventing the gland openings from becoming clogged again. This involves using specialized eyelid cleansers, such as pre-moistened wipes or hypochlorous acid sprays, to remove debris, makeup residue, and bacteria from the eyelid margins.
Dietary modifications also play a supportive role in improving the quality of the meibum itself. Supplementation with Omega-3 fatty acids, particularly those derived from fish oil, has been shown to have an anti-inflammatory effect that can positively influence the composition of the meibum. Omega-3s can help decrease the level of saturated fatty acids, making the oil less prone to solidification. For some patients, doctors may also prescribe topical medications, such as anti-inflammatory or immunomodulatory eye drops, to manage the chronic inflammation underlying MGD.

