Preparing for a physical takes about 30 minutes of effort the day before and can make the entire visit more productive. The basics: gather your medication list, know your family health history, fast if bloodwork is expected, and wear clothes that are easy to remove. Beyond logistics, the real preparation is mental. Knowing what questions to ask and what screenings to expect for your age turns a routine appointment into one that actually catches problems early.
Build Your Medication List
The FDA recommends keeping a written medication list that includes every prescription drug, over-the-counter medicine, vitamin, and supplement you take. For each one, write down the name, the strength (for example, 10 mg vs. 25 mg), what you take it for, and how often you take it. Bring the physical list or a photo on your phone. Doctors need this to check for drug interactions, adjust doses, and decide which lab tests to order.
If you’ve stopped or started any medication since your last visit, note that too. Changes you made on your own, like dropping a supplement or halving a dose because of side effects, are exactly the kind of detail that gets lost without a written record.
Collect Your Family Health History
Your family health history directly influences which screenings your doctor recommends and how early they start. A complete history covers at least three generations from both sides of the family: your siblings, your parents and their siblings, and your grandparents. For each relative, try to note the condition they had and the age they were diagnosed. If a relative has passed away, include their age and cause of death when you know it.
The conditions that matter most are the ones that cluster in families: heart disease, cancer, diabetes, high cholesterol, chronic kidney disease, and Alzheimer’s. A parent who had colon cancer at 48, for instance, could move your first colonoscopy years earlier than the standard recommendation. If you’re unsure about details, even partial information is useful. You don’t need a perfect record, just an honest one.
Fasting for Blood Work
Most annual physicals include a blood draw, and two of the most common tests require an empty stomach: a lipid panel (cholesterol) and a fasting blood glucose test. You typically need to fast for 8 to 12 hours before the appointment. Water is fine and encouraged. Coffee, juice, and food are not.
Schedule a morning appointment if you can. Fasting overnight is easier than skipping lunch, and labs drawn early tend to get processed faster. If you take morning medications, ask your doctor’s office when you book whether you should take them before or after the blood draw. Most medications are fine with a sip of water, but it’s worth confirming.
Know What Screenings to Expect for Your Age
Under the Affordable Care Act, most insurance plans cover preventive screenings at no cost to you. That includes blood pressure, diabetes, and cholesterol tests, many cancer screenings, routine vaccinations like flu shots, and counseling for topics like smoking cessation and weight management. What your doctor recommends depends heavily on your age and risk factors.
In Your 20s and 30s
Screenings are relatively light. Cervical cancer screening starts at age 21. HIV screening is recommended for everyone 15 to 65. Your doctor will also screen for unhealthy alcohol and drug use, check your blood pressure, and update vaccinations. If you have a family history of heart disease or diabetes, earlier metabolic testing may be added.
In Your 40s and 50s
This is when screening ramps up significantly. Breast cancer screening with mammography begins at 40. Colorectal cancer screening starts at 45. If you’re 35 to 70 and carry extra weight, you’ll be screened for prediabetes and type 2 diabetes. Your doctor may discuss statin therapy if you’re 40 to 75 with cardiovascular risk factors. A glaucoma screening may also be recommended starting at 40.
At 65 and Older
Women 65 and older are screened for osteoporosis. Men 65 to 75 who have ever smoked should be screened for abdominal aortic aneurysm. Hearing and vision screenings become standard. Lung cancer screening applies if you’re 50 to 80 with a significant smoking history. Your doctor may also assess fall risk and screen for depression, both of which become more common in this age group.
Knowing which screenings apply to you lets you ask informed questions. If your doctor skips one you expected, ask why. If one is overdue, bring it up yourself.
Prepare Your Questions
The most underused part of any physical is the conversation. Write down three to five questions before you go. Good ones cover the areas most people forget to mention: sleep quality, mood and stress levels, changes in energy, sexual health, and any symptom you’ve been quietly ignoring. Harvard Health suggests asking directly what lifestyle changes would improve your overall health, a broad question that gives your doctor room to address whatever stands out most in your results.
If you’ve noticed something new since your last visit, like a mole that changed shape, shortness of breath during exercise, or persistent joint pain, write it down. Patients routinely forget symptoms once they’re sitting on the exam table. A short list on your phone solves that problem completely.
What to Wear
Wear loose, comfortable clothing that’s easy to take off. Your doctor will need to listen to your heart and lungs (a stethoscope through a thick sweater gives poor results), examine your abdomen (pants and shapewear can cover more than half of it), and check your skin. Nail polish hides nail changes. Heavy foundation makes it harder to evaluate skin conditions. You don’t need to show up bare-faced, but know that anything covering your skin limits what your doctor can see.
For a blood pressure reading, you’ll want a sleeve that rolls up past your upper arm easily. Tight long sleeves that bunch above the elbow can affect the measurement. A short-sleeved shirt under a jacket is the simplest option.
Understand Your Blood Pressure Numbers
Blood pressure is one of the first things measured at any physical, and the categories are worth knowing before you go. Current guidelines from the American Heart Association and American College of Cardiology define four levels:
- Normal: below 120/80
- Elevated: 120 to 129 systolic (the top number) with the bottom number still under 80
- Stage 1 hypertension: 130 to 139 systolic, or 80 to 89 diastolic
- Stage 2 hypertension: 140 or higher systolic, or 90 or higher diastolic
A single high reading at the office doesn’t mean you have hypertension. Stress, caffeine, a full bladder, and rushing to make your appointment can all push numbers up temporarily. But if your reading comes back elevated, your doctor will likely recommend monitoring it at home or scheduling a follow-up check. Knowing the thresholds helps you understand whether your result is a minor flag or something that needs attention now.
When to Expect Lab Results
Basic blood work like a complete blood count, metabolic panel, and urinalysis is typically processed quickly. In most labs, routine tests take anywhere from 10 to 90 minutes of actual processing time once the sample arrives. But the time from your blood draw to when you see results in a patient portal is usually 1 to 3 business days, depending on the lab’s workflow, whether the sample is sent offsite, and how your doctor’s office handles result review. Specialized tests, like thyroid panels or vitamin levels, can take longer.
If you haven’t heard back within a week, call the office. No news doesn’t always mean good news. It sometimes means results got stuck in a queue.
Sports Physicals Are Different
If you’re preparing for a sports physical rather than a standard wellness visit, the focus shifts. A preparticipation physical evaluation covers the same general systems but adds targeted cardiovascular and musculoskeletal assessments. Your doctor will check heart rhythm and sounds more carefully, evaluate joint stability and range of motion, and ask detailed questions about exercise-related symptoms like chest pain, fainting, or unusual shortness of breath. A mental health screening is also part of the standard form.
Bring any required school or league paperwork to the appointment. Most sports physicals use a standardized two-page form, one for medical history and one for the exam itself. Filling out the history section at home saves time and ensures you don’t rush through important questions about past injuries or family heart conditions.

