Removing disposable gloves the wrong way can transfer whatever’s on them straight onto your skin. The correct technique follows two simple principles: glove touches glove, then skin touches skin. Here’s exactly how to do it, step by step.
The Standard Removal Technique
This method works for any disposable glove, whether you’re cleaning with chemicals, handling raw meat, or working in a clinical setting. The CDC outlines it in seven steps:
- Pinch one glove at the wrist. Grab the outside of one glove near the cuff. Don’t let your fingers slip underneath to touch bare skin.
- Peel it off inside out. Pull the glove away from your body and down over your fingers, turning it inside out as it comes off. The contaminated surface is now trapped on the inside.
- Hold the removed glove in your still-gloved hand. Just ball it up in your palm.
- Slide your bare fingers under the second glove. Tuck your index finger (or two fingers) inside the cuff of the remaining glove at the wrist. Only skin touches skin here.
- Peel the second glove off over the first. Roll it down and inside out, wrapping the first glove inside the second. You end up with a neat little pocket of contamination, sealed away from your hands.
- Throw them away immediately. Never reuse disposable gloves.
- Wash your hands right away. Soap and water or an alcohol-based sanitizer, as soon as the gloves are off.
The whole process takes about ten seconds once you’ve practiced it a few times. The key moment people get wrong is removing the second glove. If you grab it from the outside the same way you grabbed the first, you’ve just transferred contaminants onto your bare hand, defeating the entire purpose.
Why the Technique Matters
Sloppy glove removal is surprisingly common and surprisingly risky. A randomized study published in the National Library of Medicine found that improper removal led to self-contamination in 28% of all attempts. Nearly half of those contamination events happened in more than one spot on the body. The arms were the most frequently contaminated area (33% of cases), followed by clothing on the abdomen (24%) and the lower limbs (23%).
The upper portions of protective equipment tend to carry the heaviest contamination. That study found germs on the upper part of gear were about 2.4 times more likely to cause self-contamination during removal. This makes sense: your gloved hands touch most surfaces at chest height or above, so the wrist and cuff area of a glove is often the dirtiest part.
Handwashing After Removal
Even a perfect glove removal doesn’t guarantee clean hands. Microscopic tears, pinholes, and the removal process itself can leave behind pathogens. Both the CDC and the World Health Organization are clear on this point: always clean your hands immediately after taking gloves off. The WHO states directly that glove use does not replace handwashing and does not change when you need to do it.
Soap and water for at least 20 seconds is the gold standard. Alcohol-based hand sanitizer (at least 60% alcohol) works when soap isn’t available, with one exception: if your hands are visibly soiled, sanitizer alone isn’t enough.
When to Change Gloves
Knowing when to remove gloves is just as important as knowing how. You should take gloves off and put on a fresh pair in any of these situations:
- The gloves are torn or punctured. Even a small hole compromises the barrier.
- You’re switching tasks. Moving from a dirty surface to a clean one while wearing the same gloves just spreads contamination.
- They’re visibly soiled. Blood, chemicals, or food residue on the outside means the gloves have done their job and need replacing.
- You’re moving between people. In any caregiving context, fresh gloves for each person prevents cross-contamination.
A common mistake is wearing the same pair of gloves for an extended period, treating them like reusable hand armor. Disposable gloves degrade with time, sweat, and friction. The longer you wear them, the more likely they are to develop invisible micro-tears.
Removing Two Pairs of Gloves
In high-risk settings like handling hazardous materials, some people wear two layers of gloves. The removal process follows the same core logic, just applied twice. Remove the outer pair first using the standard technique (glove-to-glove, then skin-to-skin). At this point, your inner gloves are still on and relatively clean. Then repeat the process for the inner pair. Wash your hands after the final pair comes off.
The critical rule with double gloving: treat the outer pair as contaminated and the inner pair as your new “clean” surface. If the outer gloves touched something hazardous and you accidentally touch the inner gloves with the contaminated outer surface, the inner pair is compromised too, and you should treat it accordingly.

