OxyShred is taken by mixing one scoop with 10 ounces of cold water, ideally first thing in the morning on an empty stomach. For best results, the manufacturer recommends up to two servings per day, with the second serving timed before exercise or in the early afternoon on rest days.
Basic Serving Size and Mixing
Each serving is one scoop mixed into 10 ounces (about 295 ml) of chilled water. Shake or stir it well since the powder can clump if you just dump it in. Cold water is recommended over room temperature, partly for taste and partly because the ingredients dissolve more evenly. You can use a shaker bottle or just a regular glass.
When to Take Your First Serving
Your first scoop should go down first thing in the morning on an empty stomach. This timing matters because the product contains ingredients like acetyl L-carnitine, which helps shuttle fatty acids into your cells to be burned for energy. Taking it before you eat gives those compounds a window to work while your body is already in a fasted state and more likely to tap into fat stores.
If you work out in the morning, this first serving doubles as your pre-workout. Drink it about 15 minutes before you start training so the caffeine and other active ingredients have time to kick in.
When to Take the Second Serving
On training days, the second scoop goes down 15 minutes before your workout. If you already used your first serving as a pre-workout in the morning, take the second one in the early afternoon instead. On rest days with no exercise, the same pattern applies: one upon waking, one in the early afternoon.
A clinical trial registered on ClinicalTrials.gov that studied OxyShred used this exact protocol, having participants start with one daily dose for the first week before stepping up to two doses. If you’re new to thermogenic supplements, that graduated approach is worth copying. Spend at least a week on a single scoop to see how your body handles the stimulants before adding a second.
Caffeine Levels Across Versions
The original OxyShred contains 150 mg of caffeine per scoop. That’s roughly equivalent to a strong cup of coffee. If you take two scoops per day, you’re getting 300 mg of caffeine from OxyShred alone, which is already a significant chunk of the 400 mg daily limit most health guidelines suggest for adults.
OxyShred Hardcore bumps the caffeine to 275 mg per scoop, nearly double the original. Two servings of Hardcore would put you at 550 mg of caffeine daily, well above that general guideline. If you’re using the Hardcore version, one scoop per day is a safer starting point, and many people find that’s enough.
There’s also a stimulant-free version for people who are sensitive to caffeine or who prefer to get their caffeine from coffee. This lets you control your stimulant intake separately.
Combining OxyShred With Coffee or Pre-Workout
You can drink coffee and OxyShred on the same day, but you need to watch your total caffeine. One scoop of the original formula plus a standard coffee puts you around 250 to 300 mg, which most people tolerate fine. Two scoops plus coffee starts pushing past 400 mg, where jitters, a racing heart, and poor sleep become more likely.
If you want both, space them apart by at least a couple of hours rather than drinking them back to back. Stacking OxyShred with a separate pre-workout supplement is riskier since most pre-workouts contain 150 to 300 mg of caffeine on their own. That combination can easily double your intended intake. If you’re using OxyShred as your pre-workout, skip the additional pre-workout product entirely.
Both caffeine and thermogenic ingredients can have a mild diuretic effect, so drink extra water throughout the day to stay hydrated, especially during training.
Empty Stomach or With Food
The official directions specify an empty stomach for the morning dose. Eating before your first serving won’t make the product dangerous, but it can slow absorption and blunt the energy kick. Fat-burning ingredients work more efficiently when they’re not competing with a meal for digestion.
Your second serving doesn’t need to be fasted. If it falls in the early afternoon, having eaten lunch beforehand is fine. The more important factor for the second dose is timing it early enough that the caffeine doesn’t interfere with your sleep. Most people should avoid taking it within six hours of bedtime.
Getting the Most Out of Each Scoop
OxyShred is a thermogenic supplement, which means it’s designed to slightly raise your metabolic rate and help mobilize fat. It’s not a replacement for a calorie deficit. You’ll see the best results when you combine it with regular exercise and a diet that puts you in a moderate caloric deficit. The energy and focus boost from the caffeine can make workouts feel easier, which indirectly helps you burn more and train harder.
Start with one scoop per day for at least a week. Move to two scoops only after you’re confident you tolerate the stimulants well. Track your sleep quality closely during the first two weeks, since even people who handle caffeine well sometimes find that a second daily dose disrupts their rest if the timing isn’t right. If your sleep suffers, move the second serving earlier in the day or drop back to one scoop.

