How to Treat Dry Eyes: Drops, Plugs, and More

Dry eyes improve with a combination of home care, over-the-counter drops, and, when needed, prescription treatments. The right approach depends on what’s causing the problem: over 85% of dry eye cases stem from oil glands in the eyelids not working properly, which lets tears evaporate too fast. A smaller share, roughly 10%, comes from the tear glands simply not producing enough fluid. Many people have a mix of both.

Start With Warm Compresses

If your dry eye is driven by poor oil production from the eyelid glands (which is the most common type), warm compresses are one of the most effective things you can do at home. The goal is to soften the thickened oils clogging those glands so they flow freely again and form a protective layer over your tears. Research on meibum (the oily substance these glands produce) shows that heating it to about 40 to 42°C brings it to a fluid, disordered state. Because heat dissipates through the eyelid skin, the surface temperature of the compress needs to be a bit higher, around 45 to 47°C, to deliver enough warmth to the glands underneath.

A warm, damp washcloth works but cools quickly. Microwavable eye masks or bead-filled compresses hold heat longer and more evenly. Aim for about 10 minutes per session once or twice a day. After removing the compress, gently massage your closed eyelids from top to bottom on the upper lid and bottom to top on the lower lid. This helps push softened oils out of the glands and onto the eye surface.

Choosing the Right Artificial Tears

Artificial tears are the first-line treatment most people reach for, and the evidence supports using them about four times a day. Symptoms typically improve within a month of regular use at that frequency, though measurable changes to the eye surface can take several months.

The most important choice isn’t the brand. It’s whether the drops contain preservatives. Multi-dose bottles almost always include a preservative called benzalkonium chloride to prevent bacterial growth after opening. That preservative is a known irritant: it has toxic, inflammatory, and detergent-like effects on the eye surface, and it can actually worsen dry eye over time. If you’re using drops only once or twice a day, a preserved bottle is generally fine. But if you need drops four or more times daily, or if you have moderate to severe symptoms, switch to preservative-free single-use vials. Preservative-free formulations are recommended for all types of dry eye, but they’re especially important for sensitive eyes or frequent use.

You’ll also notice different formulations on the shelf. Thinner, watery drops provide quick relief but don’t last long. Thicker gel drops and ointments coat the surface longer but can temporarily blur your vision, making them better suited for bedtime.

Reduce Tear Evaporation Throughout the Day

Prolonged screen time cuts your blink rate by 40 to 60%. Normal blinking spreads tears across the eye and stimulates oil release from the eyelid glands. When you’re focused on a screen, you blink less often and less completely, and your tear film breaks down faster between blinks. One study found that people with minimal screen exposure blinked about 18 times per minute, while heavy users dropped to around 14.

The practical fix is the 20-20-20 rule: every 20 minutes, look at something 20 feet away for 20 seconds. This naturally triggers full blinks. You can also consciously practice slow, deliberate blinks a few times per hour. Positioning your monitor slightly below eye level so you look downward reduces the exposed surface area of your eye, slowing evaporation.

Other environmental adjustments that help: point car vents and fans away from your face, use a humidifier in dry or air-conditioned rooms, and wear wraparound glasses or moisture chamber glasses outdoors on windy days. If you use a CPAP machine for sleep apnea, check your mask fit carefully. Air leaking from the top of a nasal mask can blow directly into your eyes all night, causing significant morning dryness. Adjusting the straps, making sure the mask doesn’t sit too high on the bridge of your nose, or switching to a better-fitting mask size can solve the problem.

Prescription Eye Drops

When over-the-counter drops and home care aren’t enough, prescription options target the underlying inflammation or tear production deficit. The two main categories work quite differently.

Cyclosporine (the active ingredient in Restasis and its generic versions) and lifitegrast (Xiidra) both suppress the immune cells that drive chronic inflammation on the eye surface, but through different pathways. Cyclosporine blocks a specific enzyme in those immune cells, while lifitegrast prevents them from binding to and damaging tissue. Both are applied as drops twice daily. The key thing to know is that these are slow-acting treatments. Cyclosporine can take three to six months to show meaningful improvement in tear production. In clinical trials, only about 11 to 17% of patients on cyclosporine achieved a large improvement in tear volume after six months, compared to under 5% on placebo. These drops often sting or burn initially, which gets better over weeks.

A newer option takes a completely different approach. Varenicline nasal spray (Tyrvaya) is spritzed into the nose, not the eyes. It activates a nerve pathway that signals the tear glands to produce more tears. The speed difference is striking: in clinical trials, about half of patients saw a large improvement in tear production within just four weeks, compared to the months required by cyclosporine. The most common side effect is sneezing.

In-Office Procedures

Punctal Plugs

Your tears drain from the eye surface through tiny openings called puncta at the inner corners of your eyelids. Punctal plugs are small devices inserted into those openings to slow drainage and keep tears on the eye longer. The procedure takes a few minutes and is painless.

Doctors typically start with temporary collagen plugs that dissolve on their own in 4 to 14 days. This trial period lets you experience what better tear retention feels like and checks whether blocked drainage causes any overflow tearing. If the temporary plugs help, longer-lasting silicone plugs can be placed. Both types have been shown to increase tear volume and improve tear film stability. Silicone plugs stay in place indefinitely but can be removed if needed.

Intense Pulsed Light Therapy

For dry eye driven by clogged oil glands, intense pulsed light (IPL) therapy uses controlled flashes of light applied to the skin around the eyes. It works through several mechanisms at once. The heat from the light warms and liquefies thickened oils in the glands. The light energy also targets abnormal blood vessels along the eyelid margin that feed inflammation, destroying them and cutting off a major source of inflammatory signals. IPL has been shown to reduce inflammatory enzymes in tear fluid, stimulate the oil-producing cells to become more active, and even kill Demodex mites that can colonize eyelash follicles and worsen gland dysfunction.

A typical course involves three to four sessions spaced two to six weeks apart. In one early study, 87% of patients saw improved tear film stability after four sessions. Results tend to build over the treatment course, and some people benefit from periodic maintenance sessions afterward. IPL is not covered by most insurance plans and typically costs several hundred dollars per session.

Omega-3 Fatty Acids

Fish oil and flaxseed oil supplements are widely recommended for dry eye, and there is some biological rationale: omega-3 fatty acids have anti-inflammatory properties and may improve the quality of the oil layer in your tears. However, the evidence is mixed. A large clinical trial funded by the National Eye Institute found no significant benefit over placebo after 12 months. Still, many eye care providers continue to suggest them, particularly for patients with obvious oil gland dysfunction. If you try them, give it at least three months before judging whether they help.

Putting a Treatment Plan Together

Dry eye treatment works best as a layered approach. Start with the basics: warm compresses, preservative-free artificial tears four times a day, and environmental changes like adjusting your screen habits and humidity levels. Give these measures a solid month. If symptoms persist, that’s the point where prescription anti-inflammatory drops or tear-stimulating nasal spray can add meaningful relief, though the timeline for improvement varies from weeks to months depending on which option you use. Procedures like punctal plugs or IPL therapy are typically reserved for cases that don’t respond adequately to drops alone, or for people with clearly dysfunctional oil glands visible on exam. Most people find a combination that brings their symptoms to a manageable level, even if complete elimination of dryness isn’t always realistic.