Frankincense oil can be applied topically to painful areas when properly diluted with a carrier oil, typically at a 2% concentration (about 12 drops of frankincense oil per ounce of carrier). It works by blocking several inflammatory pathways in the body, and a small but growing number of clinical trials support its use for joint pain in particular. Here’s how to use it effectively and safely.
Why Frankincense Works for Pain
The resin that frankincense oil comes from contains compounds called boswellic acids. These act on pain and inflammation through multiple routes at once. They block an enzyme responsible for producing leukotrienes, a group of molecules that drive inflammation in joints, muscles, and other tissues. They also suppress the body’s main inflammatory signaling pathway, which reduces the production of several key inflammatory chemicals, including the same enzyme that NSAIDs like ibuprofen target.
Beyond just blocking inflammation, boswellic acids shift the behavior of immune cells. They discourage immune cells from staying in their aggressive, pro-inflammatory state and nudge them toward a calmer, anti-inflammatory role. They also protect cartilage by reducing the activity of enzymes that break down joint tissue. This combination of effects is why frankincense has drawn interest for chronic pain conditions rather than just acute injuries.
Choosing the Right Type
Not all frankincense oils are equal for pain relief. The species matters significantly. Boswellia serrata contains far higher concentrations of the boswellic acids responsible for anti-inflammatory effects. In chemical analyses, B. serrata resin contained 25% beta-boswellic acid compared to just 0.5% in Boswellia carterii (sometimes sold as Boswellia sacra). Across nearly every measured boswellic acid compound, serrata outperformed carterii by a wide margin.
When shopping, look for oils or extracts specifically labeled as Boswellia serrata. Check that the label lists the species name, not just “frankincense.” B. carterii is more common in perfumery and general aromatherapy, so it’s easy to grab the wrong one if you’re focused on pain management.
How to Apply It Topically
Frankincense essential oil should never be applied undiluted to skin. Mix it with a carrier oil first. The standard dilution ratios work like this:
- 1% (mild, for sensitive skin): 6 drops of frankincense per 30 mL (1 ounce) of carrier oil
- 2% (standard for pain relief): 12 drops per 30 mL of carrier oil
- 0.5% (for facial use or very sensitive skin): 3 drops per 30 mL of carrier oil
For pain, the 2% dilution is the most commonly recommended starting point. You can use jojoba or fractionated coconut oil as your carrier for a light, non-greasy feel that absorbs well. Sweet almond oil provides a richer texture that works nicely for massage but should be avoided if you have a nut allergy. Grapeseed oil is another good lightweight option.
Massage the blend directly into the painful area using firm, circular strokes. For joint pain, work the oil around and over the entire joint rather than just the single point that hurts most. Apply two to three times daily for consistent results. Before your first use, test a small amount on the inside of your wrist and wait 24 hours to check for any skin reaction.
Evidence for Knee and Joint Pain
The strongest clinical evidence for topical frankincense involves knee osteoarthritis. In a randomized, double-blind, placebo-controlled trial published in BMC Research Notes, participants applied a topical frankincense extract solution to their knees daily for four weeks. The results were striking across every measure.
Pain scores dropped from a median of 16 at baseline to 4 in the frankincense group, compared to a drop from 15 to only 8 in the placebo group. Joint stiffness scores fell from 6 to 2 with frankincense versus 6 to 4 with placebo. Physical function scores, which measure how well people could walk, climb stairs, and perform daily activities, improved by more than half in the treatment group (from about 47 to 22) while the placebo group saw only modest improvement (48 to 36). The overall disability score was cut by roughly two-thirds in the frankincense group.
These differences were all statistically significant, meaning they were very unlikely to be due to chance. Four weeks was enough to see meaningful improvement, which suggests topical frankincense doesn’t require months of use before you notice a difference.
Using Frankincense Through Inhalation
Adding a few drops of frankincense oil to a diffuser or a bowl of hot water and inhaling the steam is a common aromatherapy approach. While the topical route delivers boswellic acids directly to painful tissues, inhalation may offer a complementary relaxation effect. Stress and muscle tension amplify pain perception, and many people find frankincense’s warm, resinous scent calming. However, the direct analgesic evidence for inhaled frankincense is limited compared to topical application. If you’re choosing one method specifically for pain, topical is the stronger bet.
What Not to Do
Some essential oil companies market frankincense for internal use, suggesting you add drops to water or take it in capsules. The FDA does not recognize any essential oil as safe and effective for treating disease. In a 2022 warning letter, the agency classified essential oils marketed with therapeutic claims as unapproved drugs, noting that no adequate clinical studies support their internal use for the conditions claimed. Swallowing concentrated essential oils also risks irritating your esophagus and stomach lining.
If you want the benefits of oral boswellic acids, standardized Boswellia serrata extract supplements (sold as capsules or tablets with a specified percentage of boswellic acids) are a more studied and controlled option than drinking essential oil.
Interactions to Watch For
Boswellia may increase bleeding risk when combined with blood-thinning medications like warfarin, according to Memorial Sloan Kettering Cancer Center. If you take anticoagulants or antiplatelet drugs, talk with your prescriber before adding frankincense to your routine, whether topical or oral. The same caution applies if you’re scheduled for surgery, since increased bleeding risk matters in that context too.
Boswellia can also potentially interact with anti-inflammatory medications you’re already taking. Using topical frankincense alongside oral NSAIDs isn’t necessarily dangerous, but the overlapping mechanisms mean you should pay attention to how your body responds rather than assuming more is always better.
A Simple Routine for Pain Relief
A practical daily approach looks like this: mix 12 drops of Boswellia serrata frankincense oil into one ounce of jojoba or fractionated coconut oil. Store the blend in a dark glass bottle away from heat. Apply it to the affected area in the morning, again in the afternoon if needed, and before bed. Massage it in for at least one to two minutes per application to help the oil absorb and to increase blood flow to the area.
For larger areas like the lower back, you may want to double the batch size. For smaller joints like fingers or wrists, a half-batch is plenty. Give the routine at least three to four weeks before judging whether it’s helping, since that’s the timeframe over which clinical improvements have been documented. Many people notice some relief within the first week, with continued improvement over the following weeks.

