Gas drops contain simethicone, a silicone-based ingredient that works by lowering the surface tension of gas bubbles in your digestive tract so they combine into larger bubbles your body can expel more easily. They’re available over the counter for both adults and infants, and they typically start working within about 30 minutes. Here’s how to use them correctly depending on who they’re for.
How Gas Drops Work
Simethicone is a surfactant, not a drug that gets absorbed into your bloodstream. It acts physically on the gas already in your stomach and intestines, breaking the frothy layer of tiny bubbles into fewer, larger ones. Those bigger bubbles are easier to pass through burping or flatulence. Because simethicone stays in the gut and passes through unchanged, it has an extremely low risk of side effects or interactions with other medications.
Dosage for Adults and Teenagers
The standard adult dose depends on the form you’re taking. For capsules or regular tablets, the usual range is 60 to 125 mg taken four times a day. For chewable tablets, the dose is 40 to 125 mg four times daily, or 150 mg three times daily after meals. Liquid suspensions are typically dosed at 40 to 95 mg four times a day. Regardless of form, take each dose after meals and again at bedtime. Do not exceed 500 mg in a 24-hour period.
Chewable tablets need to be chewed thoroughly before swallowing. Capsules should be swallowed whole. If you’re using a liquid form, shake the bottle well before measuring your dose.
Dosage for Infants
Infant gas drops come as a concentrated liquid suspension. The product packaging includes a dosing chart based on your baby’s weight, and weight is more accurate than age for choosing the right amount. Use the syringe that comes in the box rather than a household spoon or a different dropper, since those can deliver the wrong volume.
To measure a dose: remove the cap, insert the syringe, and pull back to the line indicated on the chart. If you overshoot, simply push the plunger back down to the correct mark. Dispense slowly into the inside of your baby’s cheek. You can give doses after feedings and at bedtime, repeating as needed up to 12 times per day.
If your baby resists the syringe, you can mix the dose into one ounce of cool water, formula, or breast milk. Don’t add it to a full bottle, though. A small amount of liquid ensures your baby gets the entire dose.
What to Expect After Giving Them
Relief generally begins within 30 minutes. You may notice your baby passing gas or burping more easily, or an adult may feel bloating and pressure start to ease. Simethicone doesn’t prevent new gas from forming, so the effect is temporary. That’s why the dosing schedule allows for multiple doses throughout the day.
It’s worth knowing that clinical evidence for gas drops in babies with colic is mixed. A large randomized trial of 83 infants found that simethicone performed no better than a placebo at reducing colic symptoms. About 54% of treatment periods showed improvement, but the improvement rate was the same whether infants received simethicone or the placebo. Even babies whose parents specifically reported gas-related symptoms showed no additional benefit from simethicone over placebo. That doesn’t mean gas drops never help an individual baby, but colic is complex, and gas drops alone may not be the solution.
Tips for Getting the Most Out of Gas Drops
Timing matters more than people realize. Taking gas drops after a meal catches the gas as it forms during digestion. If you take them on an empty stomach hours before eating, the simethicone may pass through before it has much work to do.
For infants, pairing gas drops with other comfort measures often works better than drops alone. Bicycle leg movements, gentle tummy pressure, upright holding after feeds, and thorough burping during and after feeding all help move gas along mechanically. Gas drops can complement these techniques but shouldn’t be the only strategy.
Store the bottle tightly capped. Always shake liquid forms before each use, since the active ingredient can settle. Check the expiration date, especially if you’re pulling a bottle from a previous baby’s era out of the medicine cabinet.
Signs That Gas May Be Something More Serious
Most gassy babies are perfectly healthy and continue growing normally. But certain symptoms alongside fussiness suggest you should call your pediatrician: refusal to eat or multiple missed feedings, recurring vomiting after meals, fewer wet diapers than usual, or a baby who seems less alert or playful than normal.
Some situations call for immediate emergency care. These include a fever of 100.4°F or higher in a baby under 3 months old, bright green vomit (a possible sign of bowel obstruction), extreme sleepiness where the baby is difficult to wake, labored breathing with grunting or rib pulling, a hard swollen belly with inconsolable crying, blood in vomit or stool, or no wet diaper for six or more hours.

