YAG vitreolysis is a non-invasive, laser-based procedure used to treat symptomatic eye floaters, which are small, mobile shadows in the field of vision. These floaters are vitreous opacities, consisting of clumps of collagen fibers within the eye’s vitreous gel. The treatment is designed for floaters that significantly interfere with daily life, such as reading or driving. By using focused laser energy, the procedure aims to break down these opacities, eliminating them or reducing them to a size that no longer casts a shadow on the retina. The process is typically performed in an office setting and offers a less invasive alternative to surgical vitrectomy.
How the Laser Breaks Down Floaters
The technique relies on a specialized Nd:YAG laser, which emits short, high-power pulses of light. This laser energy is precisely focused onto the vitreous opacity, initiating photodisruption. The highly concentrated energy causes the target tissue to ionize, instantly creating a tiny burst of plasma with a temperature exceeding 4,000°C.
This rapid plasma expansion generates an acoustic shockwave that travels through the vitreous humor. The mechanical energy from this shockwave fragments the collagen and hyaluronic acid molecules forming the floater’s structure. The vitreous opacity is either vaporized completely or broken down into much smaller particles and gas bubbles.
The goal is to convert the large, visually disruptive floater into remnants small enough to settle out of the central line of sight or dissolve entirely. The resulting smaller particles and micro-gas bubbles are often visible to the patient as temporary dark specks immediately after the procedure. These gas bubbles quickly dissipate, and the smaller debris is gradually absorbed by the eye over time.
Criteria for Patient Suitability
The success and safety of YAG vitreolysis depend heavily on careful patient selection, as not all floaters are suitable for laser treatment. Ideal candidates often have a specific type of floater called a Weiss ring, a large, ring-shaped opacity that forms after a complete posterior vitreous detachment (PVD). These dense, well-defined opacities are typically located centrally and are excellent targets for the laser.
The floater must be situated at a safe distance from the eye’s sensitive structures, primarily the crystalline lens and the retina. Physicians require the floater to be at least 5 millimeters away from the natural lens to prevent cataract formation. Also, the floater must be at least 3 millimeters from the retina to avoid thermal or shockwave damage.
Floaters that are very close to the retina, or those that are diffuse and stringy, are less amenable to safe and effective treatment. Patients are typically only considered if their symptoms have persisted and been visually disruptive for a minimum of six months. Before treatment, a comprehensive eye examination rules out underlying active retinal conditions, such as tears or inflammation, which would exclude a patient from the procedure.
The Treatment Experience
Before the procedure, the eye is prepared with dilating drops to widen the pupil, allowing a clearer view of the floater. A topical anesthetic drop is applied for comfort, and a specialized contact lens is placed onto the eye to help focus the laser beam. This lens magnifies the structures and helps the physician maintain a stable view of the vitreous opacity.
The patient sits upright at a machine similar to a standard eye examination microscope, known as a slit lamp, which houses the Nd:YAG laser. The physician aims the laser at the floater through the contact lens, delivering short bursts of energy. Patients perceive bright flashes of light and may hear a faint clicking sound as the laser fires.
The treatment session typically ranges from 10 to 30 minutes, depending on the size and number of floaters targeted. Immediately afterward, the patient may notice small, dark specks moving in their vision, which are the fragmented remnants and gas bubbles. These effects are temporary and usually resolve quickly. Post-procedure care often involves anti-inflammatory eye drops to manage mild irritation.
Managing Post-Procedure Risks
YAG vitreolysis is considered a low-risk, non-surgical option, but patients should be aware of potential complications, though they are generally rare. A common event is a temporary elevation of intraocular pressure (IOP) shortly after the laser application. This is managed by measuring the IOP immediately following the procedure and, if necessary, administering pressure-lowering eye drops.
More serious, though infrequent, risks include damage to the lens, which can accelerate cataract formation. This risk is mitigated by ensuring the floater is a safe distance from the lens. The shockwave from the laser can also, in rare instances, cause collateral damage to the retina.
Retinal damage can manifest as a hemorrhage, a tear, or, in severe cases, a retinal detachment. Patients are advised to contact their eye care professional immediately if they experience a sudden increase in floaters, flashing lights, or a curtain-like shadow in their vision. Careful patient selection and precise laser delivery are the primary methods used to minimize these potential adverse events.

