The term “blood infection” often suggests a simple, transmissible disease like a cold or the flu. Medically, this condition is known as bacteremia or the more serious condition, sepsis. These terms describe a dangerous internal state where microorganisms have entered the body’s sterile bloodstream, or where the body is mounting a harmful, systemic response to an infection. Understanding this underlying medical reality, which is distinct from a contagious illness, clarifies the contagiousness of this systemic health crisis.
Clarifying What a Blood Infection Is
The bloodstream is normally a sterile environment. The presence of viable bacteria, a state called bacteremia, is the detection of microbes in the blood. Bacteremia can be transient and often cleared by the immune system without causing illness. If the immune system fails to contain the bacteria, the infection can progress to a more serious stage.
The term “blood infection” most often describes sepsis, which is a life-threatening organ dysfunction caused by the body’s dysregulated response to an infection. Sepsis is not an infection itself, but a severe systemic response to a pathogen that has entered the bloodstream or is causing a severe localized infection elsewhere. This systemic inflammatory response can quickly lead to tissue damage, organ failure, and death. Sepsis is a medical emergency requiring rapid intervention to prevent shock and multisystem failure.
Transmissibility of the Condition
Sepsis or bacteremia is generally not transmissible from one person to another through casual contact, air, or touch. This is because the condition is an internal cascade of events resulting from a patient’s own immune system malfunctioning in response to an existing infection. Sepsis is the body’s internal failure to cope with an infection, and this failure cannot be passed like a respiratory virus.
It is necessary to distinguish between the primary pathogen and the resulting systemic condition. The bacteria, virus, or fungus that initially caused the infection (e.g., Staphylococcus aureus or E. coli) may be contagious, spreading through coughing, contaminated surfaces, or direct contact. However, a person who catches the pathogen will not automatically develop a bloodstream invasion. The new host must first develop a localized infection, which would then have to progress into their bloodstream, requiring a breakdown in their internal defenses.
Primary Sources of Infection
Sepsis and bacteremia are complications of an infection that started elsewhere in the body, not in the blood itself. The bloodstream becomes involved when a localized infection is severe or left untreated, allowing microorganisms to breach the body’s natural barriers and enter the circulation.
The most common starting points for these infections include:
- Pneumonia, an infection of the lungs, which accounts for a significant percentage of cases that progress to sepsis.
- Urinary tract infections (UTIs), where bacteria from the bladder or kidneys can travel through the urinary system and reach the bloodstream.
- Infections of the digestive system, such as a perforated bowel or appendicitis, which represent a substantial risk due to the high concentration of bacteria in the gut.
- Skin and soft tissue infections, including cellulitis or abscesses, which allow bacteria to enter the blood if the infection is deep or extensive.
- Infections associated with medical devices, such as central intravenous lines or urinary catheters, which provide a direct route for microorganisms to bypass the skin’s defense mechanism and enter the circulation.
Steps for Risk Reduction
Since a bloodstream infection is a complication of an existing localized infection, the most effective preventative strategy involves rigorous control of the initial infection.
Maintaining stringent hand hygiene is an effective barrier against the spread of pathogens that can lead to sepsis. Hands should be washed thoroughly with soap and water or an alcohol-based rub, especially after using the restroom, before eating, and after interacting with wounds. Proper care of cuts, scrapes, and other wounds is also necessary to prevent bacteria from breaching the skin barrier.
Any open wound should be kept clean, covered with a sterile dressing, and monitored for signs of developing infection, such as increasing redness or discharge. Timely recognition and treatment of localized infections, like pneumonia or UTIs, is important to prevent them from escalating.
Adherence to recommended vaccination schedules, such as those for influenza and pneumococcal disease, can reduce the risk of contracting common infections that lead to sepsis. Furthermore, managing chronic health conditions like diabetes effectively minimizes the risk of infection. In healthcare settings, meticulous aseptic technique for the insertion and maintenance of medical devices is mandatory to prevent the direct entry of pathogens into the bloodstream.

