Buffalo Trace bourbon is considered gluten free, even though it’s made from grains that contain gluten. The distillation process removes gluten proteins from the final spirit, and Buffalo Trace doesn’t add flavorings or other ingredients after distillation that would reintroduce gluten. For most people with celiac disease or gluten sensitivity, this bourbon is safe to drink.
What’s in Buffalo Trace Bourbon
Buffalo Trace uses what’s known as Mash Bill 1: roughly 89.5% corn, 7% rye, and 3.5% malted barley. Barley is one of the three primary gluten-containing grains (along with wheat and rye), and rye is another. So before distillation, the mash that becomes Buffalo Trace absolutely contains gluten.
This is where the confusion starts for most people. If the grain bill includes barley and rye, how can the final product be gluten free? The answer comes down to what happens during distillation.
How Distillation Removes Gluten
Distillation works by heating a liquid until certain compounds vaporize, then cooling those vapors back into liquid form. Gluten is a protein, and proteins are not volatile, meaning they don’t vaporize. When the bourbon is distilled, the alcohol and flavor compounds rise as vapor and get collected, while the proteins (including gluten) stay behind in the still.
This isn’t a partial reduction. Proper distillation removes all protein from the distillate. The FDA has confirmed that distillation eliminates protein, including gluten, when good manufacturing practices are followed. The Alcohol and Tobacco Tax and Trade Bureau (TTB) now permits distilled spirits made from gluten-containing grains to carry a “gluten-free” label, as long as manufacturers can demonstrate no protein is present in the final product and no gluten-containing materials are introduced after distillation.
Why Straight Bourbon Is Lower Risk Than Flavored Spirits
The real gluten risk with distilled spirits comes from what happens after distillation. Flavored whiskeys, cream liqueurs, and certain other spirits may have ingredients added post-distillation that contain gluten. Ouzo, for example, sometimes has grains added after distilling.
Buffalo Trace is a straight bourbon. Under U.S. regulations, straight bourbon cannot contain added flavoring, coloring, or other spirits. What’s in the bottle is distilled spirit that has been aged in new charred oak barrels. There’s no step in the process where gluten-containing ingredients get reintroduced.
The Testing Limitation
One thing worth understanding: there’s currently no scientifically validated method to measure the exact parts per million of gluten in fermented or hydrolyzed products. The standard gluten tests (called ELISA tests) were designed for intact gluten proteins in foods like bread, and they don’t translate cleanly to alcohol. The TTB has stated that labeling a specific ppm number on distilled spirits would be misleading, since no validated method exists to produce that number.
What can be tested reliably is the presence or absence of protein fragments in the distillate. The FDA uses this approach to verify gluten-free claims on distilled products. If no protein or protein fragments are detectable, gluten isn’t present. For a properly distilled bourbon like Buffalo Trace, those tests come back clean.
Why Some People Still React
A small number of people with celiac disease report symptoms after drinking distilled spirits made from gluten grains, even though the science says the gluten shouldn’t survive distillation. There are a few possible explanations. Cross-contact during manufacturing, though unlikely with a major distillery following good practices, is one. Individual sensitivity to trace compounds that aren’t technically gluten is another. And sometimes the symptoms attributed to the bourbon are actually caused by something else consumed alongside it, like beer, mixers, or bar snacks.
Beyond Celiac, one of the leading celiac disease organizations in the U.S., states plainly that pure distilled liquor, even when made from wheat, barley, or rye, is considered gluten free. If you’ve been diagnosed with celiac disease and haven’t tried grain-based spirits before, starting with a small amount and paying attention to how you feel is a reasonable approach. But the scientific and regulatory consensus is clear: distillation makes Buffalo Trace safe for a gluten-free diet.

