Standard drawing salve, which contains ichthammol as its active ingredient, is generally safe for topical use on minor skin issues. However, the term “drawing salve” gets applied to two very different products, and one of them carries serious risks. Understanding which product you’re dealing with is the most important safety consideration.
Two Products, One Name
The classic drawing salve sold in most pharmacies contains ichthammol at a 20% concentration. Ichthammol is derived from shale oil and has been used topically for well over a century. It’s a thick, dark ointment typically applied to splinters, boils, and minor skin irritations to help soften the skin and draw out debris or pus.
The other product sometimes called “drawing salve” is black salve, an escharotic paste that contains bloodroot (a plant extract) and zinc chloride (a caustic synthetic chemical). Black salve is marketed online as a natural treatment for skin cancer and other skin conditions, but it works by destroying tissue indiscriminately. The FDA has prohibited black salve from being marketed as a topical cancer treatment and issued warning letters to companies making health claims about it. Despite marketing language that emphasizes its botanical ingredients, zinc chloride is often the main ingredient by weight, and some formulations add DMSO to drive chemicals deeper into the skin.
If the product you’re considering contains bloodroot, zinc chloride, or is marketed for treating skin cancer or moles, it is not a standard drawing salve. It’s black salve, and the safety profile is dramatically different.
How Ichthammol Drawing Salve Works
Ichthammol softens the outer layer of skin by interacting with structural proteins in the epidermis. Lab studies on 3D skin models show that higher concentrations of ichthammol decrease the expression of proteins that hold the skin’s barrier together, specifically filaggrin and laminin. This increases skin permeability in a dose-dependent way, loosening the tissue enough to help pus drain from boils or to let embedded splinters work their way out. The ointment doesn’t actively “pull” anything out of the skin. It creates conditions that make it easier for trapped material to exit on its own.
Side Effects of Ichthammol
Ichthammol has no absolute medical contraindications. The side effects are mild and mostly cosmetic. You may notice mild skin irritation, redness, dryness, or a temporary change in skin color at the application site. These typically resolve once you stop using the ointment. The product has a strong sulfur-like odor that many people find unpleasant, and it can permanently stain fabrics, skin, and hair.
Allergic reactions are possible but uncommon. Signs of an allergic reaction include a skin rash, itching, hives, or swelling of the face, lips, tongue, or throat. If any of these develop, stop using the product and get medical attention.
How to Use It Safely
Apply a thin layer of ichthammol ointment to the affected area and cover it with a clean bandage. Change the bandage and reapply at least once daily, or whenever the bandage becomes soiled. Keep the ointment away from your eyes and mouth. Because it stains easily, use bandages or gauze you don’t mind discarding, and avoid contact with clothing or bedding you want to keep clean.
Drawing salve works best on minor, superficial skin issues: a stubborn splinter, a small boil that hasn’t opened, or a bug bite. It’s not a substitute for medical treatment of deeper infections. If the area around a boil or wound develops spreading redness, increasing warmth, red streaks, significant swelling, or if you develop a fever, those are signs of a skin infection that has progressed beyond what a topical ointment can address.
Why Black Salve Is Dangerous
Black salve destroys tissue through chemical burns. Proponents claim it selectively targets cancer cells while leaving healthy tissue intact. Research directly contradicts this. When researchers examined the tissue removed by black salve (called an eschar), it contained both cancerous and normal tissue. Multiple black salve ingredients are toxic to normal cells at low concentrations, making the claim of tumor specificity false.
In one review of cases, 20% of people who used black salve on skin lesions suffered significant deformity. Documented consequences include deep indented scars on soft tissue, destruction of nasal passages when applied near the nose, and in one case, a wound through the abdominal wall. The eschar that forms can cause lasting cosmetic and functional damage even after healing.
Perhaps most dangerously, using black salve on a suspected skin cancer can destroy the surface of the lesion while leaving deeper cancer cells behind. This creates the appearance of treatment while allowing the cancer to continue growing underneath, delaying effective medical care.
The Bottom Line on Safety
Ichthammol-based drawing salve from a pharmacy is a low-risk topical product with a long track record. Side effects are minor, allergic reactions are rare, and there are no known contraindications. The real safety concern is product confusion. If you encounter a “drawing salve” sold online that contains bloodroot, zinc chloride, or claims to treat cancer, that is black salve, and it can cause serious, permanent tissue damage. Check the ingredients list before buying, and stick with products that list ichthammol as the active ingredient.

