Yes, Levoxyl is still available in the United States. It is not listed on the FDA’s drug shortage database, and its product labeling remains active on DailyMed, the federal drug information database. If you’re having trouble finding it at your pharmacy, the issue is likely a local supply problem rather than a national discontinuation.
Why People Wonder About Levoxyl’s Availability
Levoxyl has a history that understandably makes patients nervous. In February 2013, Pfizer stopped shipping all strengths of Levoxyl and placed the product on backorder. By April of that year, King Pharmaceuticals (a Pfizer subsidiary) initiated a full recall at retail pharmacies, and the company warned that Levoxyl might not return until 2014. For patients who had been stable on the medication, this was a serious disruption, since switching between different levothyroxine products can require dose adjustments and retesting.
Levoxyl did return to the market after that recall, and it has remained available since. However, the memory of that disruption, combined with occasional local stock issues, keeps the question alive for many thyroid patients.
Current Strengths and Formulation
Levoxyl comes in 11 tablet strengths: 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, and 200 micrograms. The tablets are oval, color-coded by dose, and marked with their potency. One detail that matters to many patients: Levoxyl is gluten-free. Its inactive ingredients include microcrystalline cellulose, croscarmellose sodium, magnesium stearate, calcium sulfate dihydrate, sodium bicarbonate, and coloring additives.
This is relevant because not all levothyroxine brands share the same inactive ingredient profile. If you have celiac disease or a gluten sensitivity, Levoxyl’s formulation may be a reason your doctor specifically chose it over another option.
Levoxyl vs. Other Levothyroxine Brands
Every brand of levothyroxine contains the same active ingredient, the synthetic thyroid hormone T4. The differences between brands come down to the inactive ingredients used to form the tablet, which can affect how your body absorbs the medication and how well you tolerate it. Some patients notice changes in how they feel when they switch brands, even though the active drug is identical.
The major branded alternatives in the U.S. include Synthroid, Unithroid, and Tirosint. Tirosint is a gel capsule with very few inactive ingredients, which makes it an option for patients with multiple allergies or absorption issues. Generic levothyroxine is also widely available from several manufacturers.
One brand that is going away: Euthyrox, a levothyroxine product more commonly used in Europe, is listed on the FDA’s drug shortage database as “To Be Discontinued” due to the manufacturer ceasing production. This is a separate product from Levoxyl and does not affect Levoxyl’s supply.
What to Do if Your Pharmacy Can’t Fill It
If your pharmacist tells you Levoxyl is unavailable, ask whether the issue is temporary or specific to their distributor. Pharmacies sometimes run out of a particular brand without it reflecting a national shortage. You can ask the pharmacy to order it, try a different pharmacy, or check with a specialty or mail-order pharmacy.
If you do need to switch to a different levothyroxine brand or generic, your thyroid levels should be rechecked about six weeks after the switch. Because inactive ingredients differ between products, absorption can vary slightly, and what was the right dose on one brand may need a small adjustment on another. Staying on the same brand consistently, when possible, helps keep your levels stable.
Recent FDA Activity on Levothyroxine
In August 2025, the FDA upgraded a recall alert on levothyroxine tablets from a specific manufacturer to a class II designation, affecting over 160,000 bottles. This recall involves a particular manufacturer’s product, not the Levoxyl brand. However, recalls of any levothyroxine product can tighten supply across the board, since pharmacies may temporarily see higher demand for the remaining brands. If you’re on Levoxyl and your pharmacy’s stock seems limited, this kind of ripple effect could be a contributing factor.