Magnesium citrate is a widely available compound formed by combining the mineral magnesium with citric acid. As an over-the-counter preparation, it is commonly known for its ability to act as a saline laxative, promoting bowel movements. This article explores the uses, safety considerations, and proper administration of magnesium citrate during pregnancy. Expecting parents should consult with their healthcare provider to make informed decisions regarding its use.
Primary Use During Pregnancy: Constipation Relief
Constipation is a common complaint during pregnancy, often starting early in the first trimester. This sluggishness is largely due to the surge in progesterone, a hormone that relaxes smooth muscle tissue, including the intestinal walls. Slower intestinal movement increases water absorption, resulting in harder stools.
Later in pregnancy, the growing uterus places physical pressure on the bowel, compounding reduced motility. Additionally, iron in prenatal vitamins can contribute to or worsen constipation. Magnesium citrate is utilized for temporary relief due to its mechanism as an osmotic laxative.
The compound is poorly absorbed in the gastrointestinal tract, creating an osmotic effect that draws water from surrounding tissues into the bowel. This influx increases the volume and softness of the stool, stimulating intestinal movement (peristalsis) to encourage evacuation. This action is generally quick, often resulting in a bowel movement within a half-hour to six hours.
Safety Profile and Medical Considerations
The safety profile of magnesium citrate during pregnancy is generally acceptable for occasional, short-term use under medical guidance. However, it is not recommended as a first-line treatment due to potential side effects. Healthcare professionals usually advise lifestyle modifications first, such as increasing dietary fiber and fluid intake.
The primary safety concern with osmotic laxatives is the potential for fluid and electrolyte imbalance if overused. Excessive doses or prolonged use can cause significant diarrhea, leading to dehydration and loss of minerals like potassium. Individuals with pre-existing kidney impairment should avoid magnesium citrate entirely, as impaired function prevents the body from clearing excess magnesium, raising the risk of hypermagnesemia (magnesium toxicity).
Before initiating any over-the-counter treatment, consult with an obstetrician or prenatal healthcare provider. They can rule out serious causes of abdominal pain or bowel changes and ensure the compound will not interact with other medications. Taking the laxative only as directed and for a brief period minimizes the risk of adverse effects.
Proper Dosage and Administration
Magnesium citrate is available in liquid solution and tablet forms; dosage depends on whether it is used as a laxative or for nutritional supplementation. For occasional constipation, the liquid solution is typically recommended due to its potency and rapid action. A typical adult laxative dose ranges from 195 to 300 milliliters of the liquid solution, often taken as a single dose.
Start with the lowest effective dose suggested by a healthcare provider to minimize gastrointestinal side effects like cramping or loose stools. Consuming a full glass of water (about eight ounces) alongside the dose is important to support the osmotic action and prevent dehydration. Since the onset of action usually occurs within six hours, it is often taken in the morning or early afternoon to avoid disrupting sleep.
The tablet form is generally used for lower-dose mineral supplementation and is not preferred for immediate constipation relief. Magnesium citrate is intended for temporary relief only. If constipation persists for more than a week, or if severe symptoms such as rectal bleeding or inability to pass a bowel movement occur, seek medical attention immediately.
Clarifying Magnesium Citrate Versus Other Magnesium Forms
Magnesium is an important mineral available in several forms, each with a different primary application and absorption rate. Magnesium citrate is distinct because it is specifically suited for its laxative effect due to its high solubility and osmotic action. While highly bioavailable, its main use is for digestive support rather than increasing systemic mineral levels.
Other common forms are preferred when the primary goal is to increase the body’s overall magnesium stores. For example, magnesium glycinate is bound to the amino acid glycine, known for high absorbability and gentleness on the stomach, making it popular for addressing leg cramps or promoting relaxation. Magnesium oxide has a lower rate of systemic absorption but is sometimes used as a temporary remedy for heartburn or as a mild laxative.
Magnesium sulfate is a highly potent form used only in specific, severe medical settings, such as preventing seizures in preeclampsia. When discussing supplementation during pregnancy, the form of magnesium dictates its function. Magnesium citrate should be viewed as a short-term digestive aid, not a comprehensive daily mineral supplement.

