Heart palpitations, often described as a fluttering, pounding, or skipped beat in the chest, are a common and sometimes alarming symptom of an irregular heart rhythm. While many palpitations are harmless, they can signal a disturbance in the heart’s electrical system. Magnesium glycinate is a specific form of this mineral that has gained attention as a potential dietary supplement for supporting heart health and reducing the frequency of these rhythm changes.
Magnesium’s Role in Maintaining Cardiac Rhythm
Magnesium is an electrolyte that plays a fundamental part in regulating the heart’s electrical activity. The rhythmic contraction and relaxation of the heart muscle depend on the precise movement of other electrolytes, specifically potassium, sodium, and calcium, across cell membranes. Magnesium acts as a natural stabilizer, influencing the movement of these ions to ensure coordinated electrical signal conduction.
The mineral helps regulate the “gates” within the atrioventricular (AV) node, which controls the timing of electrical signals traveling through the heart. By controlling these gates, magnesium helps prevent excessive calcium from entering heart cells, which can lead to irregular or premature contractions. A deficiency in magnesium can disrupt this balance, potentially causing the heart to beat out of sync, which is often felt as a palpitation. Low magnesium levels are associated with an increased risk of abnormal heart rhythms.
What Makes Magnesium Glycinate Unique?
Magnesium glycinate is a chelated form, meaning the mineral is bound to the amino acid glycine. This structure is designed to enhance absorption and minimize digestive side effects compared to common forms like magnesium oxide. The chelated bond allows the magnesium to pass through the digestive system more easily, resulting in higher bioavailability, meaning more of the mineral reaches the bloodstream and tissues.
The glycine component also contributes to the supplement’s overall benefits. Glycine is known to have calming properties in the nervous system, complementing magnesium’s role in relaxing muscles and reducing excitability. This combination makes magnesium glycinate a popular choice for individuals seeking both cardiovascular support and a mild calming effect.
Clinical Evidence for Palpitation Relief
Oral magnesium supplementation can reduce the frequency and symptoms of certain benign heart rhythm disturbances, particularly in cases linked to a magnesium deficiency. Magnesium helps stabilize cardiac cell membranes and regulate the electrical impulses that trigger irregular beats. This effect is especially relevant for common palpitations known as premature ventricular contractions (PVCs) and premature atrial contractions (PACs).
Research shows that administering oral magnesium to symptomatic patients can lead to a significant reduction in their frequency. For instance, one randomized study found that patients receiving magnesium reported substantial symptom improvement compared to those receiving a placebo. The benefit of magnesium glycinate is often highlighted for palpitations exacerbated by stress or anxiety.
Magnesium supplementation is sometimes used to manage symptoms when palpitations are considered idiopathic, meaning the underlying cause is unknown, or when a deficiency is suspected. While many studies focus on intravenous magnesium for acute arrhythmias, the oral form, especially highly-absorbable glycinate, is a common strategy for long-term management and prevention. The success of magnesium is tied to its ability to restore proper ion balance.
Safe Usage and Medical Consultation
Before starting any supplement regimen for heart palpitations, consult with a healthcare provider to rule out serious underlying conditions. Palpitations can signal issues requiring immediate medical intervention or specific prescription medications, and relying solely on a supplement without a proper diagnosis is unsafe.
For most healthy adults, the recommended dietary allowance (RDA) for magnesium ranges from 310 to 420 milligrams daily. Therapeutic doses for managing palpitations may be higher, but must be determined under medical guidance. While magnesium glycinate is generally well-tolerated, excessive intake can cause side effects such as nausea, cramping, or diarrhea. Individuals with kidney impairment must be cautious, as their bodies may struggle to excrete excess magnesium, potentially leading to dangerous accumulation.

