Yes, OxyShred contains caffeine. The original OxyShred Thermogenic Fat Burner has 150 mg of caffeine per scoop, which is roughly equivalent to one and a half cups of regular brewed coffee. That said, the exact amount varies by product version, and EHPlabs also makes a completely caffeine-free option.
How Much Caffeine Is in Each Version
EHPlabs sells three main versions of OxyShred, and the caffeine content differs significantly between them:
- OxyShred Original: 150 mg of caffeine per serving. The manufacturer describes this as “only slightly higher than a strong cup of coffee,” designed to deliver smooth energy without the jittery feeling of higher-dose pre-workouts.
- OxyShred Hardcore: 275 mg of caffeine per serving. That’s nearly double the original and roughly equivalent to two and a half cups of coffee. This version is aimed at experienced supplement users who want stronger stimulation.
- OxyShred Non-Stim: Zero caffeine. This version replaces caffeine with theacrine, a compound that works on similar brain pathways to provide mild, sustained energy without raising heart rate or blood pressure the way caffeine can.
For context, a standard 8 oz cup of brewed coffee contains about 100 mg of caffeine. So one scoop of the original OxyShred puts you at about 1.5 cups’ worth, while the Hardcore version is closer to 3 cups in a single serving.
Where the Caffeine Comes From
The caffeine in OxyShred comes from caffeine anhydrous, which is simply dehydrated caffeine in powder form. It’s listed within the product’s “Mood Enhancer Matrix” alongside L-tyrosine, taurine, and an herb extract called huperzine A. The entire matrix totals 851 mg, but EHPlabs does not break out the individual milligram amounts for each ingredient on its label.
OxyShred also contains green coffee bean extract (listed as chlorogenic acid) in a separate part of the formula and bitter orange fruit extract. Green coffee bean extract contains small amounts of naturally occurring caffeine, though the primary purpose of chlorogenic acid is to support fat metabolism rather than provide stimulation. Bitter orange extract contains synephrine, a compound that can have mild stimulant-like effects on its own. Together, these ingredients mean the total stimulant load of OxyShred is slightly more complex than the 150 mg caffeine figure alone suggests.
How the Caffeine Works in This Formula
Caffeine in thermogenic supplements like OxyShred serves two purposes: energy and calorie burning. On the energy side, caffeine blocks adenosine receptors in your brain. Adenosine is the chemical that builds up throughout the day and makes you feel sleepy, so blocking it keeps you feeling alert and focused.
On the fat-burning side, caffeine has been shown to temporarily increase resting energy expenditure, meaning your body burns slightly more calories at rest after consuming it. It also helps mobilize fatty acids from stored body fat, making them available as fuel during exercise. These effects are modest on their own but are the reason caffeine is a staple ingredient in nearly every thermogenic supplement on the market.
Keeping Your Total Caffeine in Check
If you drink coffee, tea, or energy drinks alongside OxyShred, your daily caffeine total adds up quickly. One scoop of the original formula plus a morning coffee puts you at roughly 250 mg. Add an afternoon iced coffee and you’re approaching the 400 mg daily limit that most health guidelines consider safe for adults. With the Hardcore version, a single scoop plus one coffee already gets you close to that ceiling.
Timing matters too. The manufacturer recommends avoiding OxyShred within 8 hours of bedtime, since caffeine’s half-life (the time it takes your body to clear half of it) runs about 5 to 6 hours in most people. A scoop at 3 PM means a meaningful amount of caffeine is still circulating at 9 PM.
If you’re new to OxyShred, starting with a half scoop lets you gauge how you respond before committing to a full serving. People who are sensitive to caffeine, or who notice jitteriness, anxiety, or a racing heart, may find the Non-Stim version a better fit. Its theacrine-based formula works through similar brain pathways but produces a gentler, more even energy curve without the cardiovascular effects that caffeine can trigger.