Wine is more likely to worsen stomach ache symptoms than to provide relief. A stomach ache often signals irritation or inflammation within the gastrointestinal tract, and wine directly aggravates this condition due to its chemical and physical properties. Wine introduces multiple components that actively challenge the delicate lining and function of the stomach and intestines. Understanding the biological mechanisms involved clarifies why wine should be avoided when the digestive system is already compromised.
Ethanol’s Irritating Effect on the Stomach Lining
The alcohol content, or ethanol, is a direct irritant to the stomach’s protective layer, known as the gastric mucosa. Ethanol is a caustic substance that can chemically erode the mucosal barrier, leading to acute inflammation, known as gastritis. This irritation can cause a burning or gnawing sensation, transforming a mild ache into more pronounced pain. Even moderate concentrations of ethanol compromise the integrity of the stomach lining, making it vulnerable to damage from its own acid.
Ethanol also interferes with the physical movement of the digestive system. Beverages with alcohol content around or above 15% can inhibit gastric motility, which is the muscular action that moves food from the stomach into the small intestine. This delays gastric emptying, meaning the stomach contents remain in contact with the stomach wall for a longer duration. The resulting slowdown can cause nausea, excessive fullness, and bloating, which prolong the stomach ache.
Wine and Increased Gastric Acid Secretion
Wine consumption actively stimulates the stomach to produce more acid. Wine is considered a potent secretagogue, meaning it triggers cells in the stomach to release hydrochloric acid. This effect is often stronger than that produced by pure ethanol alone, demonstrating that non-alcohol components of wine also play a role.
The presence of both ethanol and organic acids naturally found in wine, such as tartaric and malic acids, encourages the acid-secreting parietal cells to increase production. This hyperacidity can lead to classic symptoms of heartburn or acid reflux, where stomach acid backs up into the esophagus. For individuals already suffering from indigestion, this surge in acid can significantly exacerbate abdominal pain.
Secondary Components Contributing to Digestive Discomfort
Several other compounds in wine can trigger gastrointestinal discomfort in sensitive individuals. Red wines contain higher levels of biogenic amines, particularly histamine, a compound involved in immune response and digestion. People with a deficiency in the enzyme diamine oxidase (DAO) may struggle to break down these histamines, leading to symptoms like flushing, headaches, and digestive distress.
Tannins, which are phenolic compounds derived from grape skins and oak barrels, contribute to the astringent quality of wine. For some people, these compounds can irritate the digestive tract and cause stomach upset or bowel irritation. Sulfites, preservatives used in winemaking, are rarely the cause of stomach pain, with true sensitivity affecting less than one percent of the population.
Safer, Effective Remedies for Stomach Aches
When suffering from a stomach ache, focusing on non-alcoholic, soothing options is the most effective path toward relief. Simple hydration is foundational, as mild dehydration can contribute to cramping and hinder the digestive process. Plain water or a sports drink with electrolytes can help restore fluid balance and support normal gut function.
Herbal and Dietary Relief
Herbal remedies offer proven relief by soothing the digestive muscles and reducing inflammation.
- Peppermint tea contains compounds that have an antispasmodic effect, relaxing painful contractions in the gut.
- Ginger root, consumed as tea or a supplement, is known for its anti-inflammatory properties and its ability to reduce nausea.
- For acid-related discomfort, baking soda (sodium bicarbonate) mixed with water can quickly neutralize excess stomach acid.
- A bland diet consisting of foods like bananas, rice, applesauce, and toast (the BRAT diet) can help rest the digestive tract.
If pain is severe, persistent, or accompanied by symptoms like fever, persistent vomiting, or bloody stools, seek medical attention.

