Endometriosis is a condition where tissue similar to the lining inside the uterus grows outside of it, leading to pain and anatomical distortion. This ectopic growth, often referred to as lesions, can affect the ovaries, fallopian tubes, and the lining of the pelvis. Magnetic Resonance Imaging (MRI) has emerged as a powerful, non-invasive method for mapping this complex disease. MRI is particularly useful because its superior soft-tissue contrast allows for the visualization of deep-seated disease that other imaging techniques might overlook.
Why MRI is Recommended for Endometriosis
While transvaginal ultrasound is often the initial imaging step, it has limitations, particularly when the disease is extensive or located in hard-to-reach areas. MRI provides a broader field of view and superior contrast resolution, making it highly effective for assessing the full extent of the condition. This detailed imaging is especially important for accurately diagnosing deep infiltrating endometriosis (DIE), where lesions penetrate the pelvic organs or surrounding structures.
The MRI scan can precisely locate lesions involving the bowel, bladder, or ureters, which are often poorly visualized during a standard ultrasound. By mapping the size, location, and depth of these lesions, the MRI helps determine the disease’s severity and guides treatment decisions. This detailed staging is extremely helpful for pre-surgical planning, allowing surgeons to anticipate complexity and ensure all specialized personnel, such as colorectal surgeons, are available if necessary.
Preparation Steps Before the Scan
Fasting
You will typically be asked to fast for four to six hours before the exam, meaning you should not eat or drink anything during this period. This fasting helps to minimize the movement of the stomach and small bowel, which can blur the resulting images.
Bladder Fullness
For optimal viewing of the pelvic organs, some facilities may require a moderate level of bladder fullness. A partially full bladder pushes loops of the small bowel out of the field of view, allowing for clearer visualization of the pelvic floor and ligaments. Patients are usually instructed to empty their bladder about an hour before the exam and then drink a small amount of fluid to achieve this moderate fullness.
Bowel and Metal Preparation
In cases where deep infiltrating endometriosis involving the rectosigmoid colon is suspected, specific bowel preparation may be necessary. This can involve following a low-residue diet for a day or two and potentially using laxatives or an enema as prescribed by your doctor. Additionally, all metal items, including jewelry, hairpins, and clothing with metallic components, must be removed before the scan because the MRI machine uses a powerful magnet.
The MRI Procedure Itself
Upon arrival, you will typically be asked to change into a hospital gown and complete a safety screening form to confirm you have no contraindications, such as certain types of metal implants. Before the scan begins, a specialized pelvic coil is often placed over your abdomen and pelvis. This coil acts as an antenna to enhance the quality and detail of the images captured by the machine.
To ensure the clearest possible images, an antispasmodic agent, such as Buscopan, may be administered intravenously just before the scan. This medication temporarily slows down the involuntary contractions of the bowel, preventing motion blur caused by peristalsis. Your medical team will first screen you for any contraindications, such as narrow-angle glaucoma.
The examination table slides into the MRI machine, positioning you in a supine, or face-up, position. The scan typically takes between 45 and 60 minutes, and the most important instruction is to remain completely still throughout the process. During the scan, the machine generates loud, repetitive banging and clicking noises, so you will be provided with earplugs or headphones, often with music, for comfort and hearing protection.
During the procedure, an intravenous line (IV) is often placed in your arm to administer a Gadolinium-based contrast dye. This contrast agent travels through your bloodstream and can help highlight areas of inflammation or active disease, making certain lesions more visible on the final images.
Understanding What the Scan Reveals
One of the most common findings is the presence of endometriomas, which are sometimes called “chocolate cysts,” typically found on the ovaries. These cysts appear distinctively bright on specific imaging sequences due to the presence of old blood products.
The scan meticulously searches for deep infiltrating endometriosis (DIE) nodules, which are often found along the uterosacral ligaments, the rectovaginal septum, and the cul-de-sac. These lesions present as thickened, fibrous tissue that may distort the normal pelvic anatomy and cause the obliteration of spaces. The MRI can also detect adhesions, which are bands of scar tissue that pull organs out of their usual position, such as “kissing ovaries” where the ovaries are tethered together.
Beyond the reproductive organs, the images are scrutinized for any involvement of adjacent structures, including the walls of the rectum, sigmoid colon, and bladder. The findings from the MRI are used by your specialist to accurately stage the disease and formulate a personalized treatment plan, which may involve hormonal therapy or surgical excision.

