Spotted Spurge (Euphorbia maculata), also known as spotted sandmat or milk purslane, is a low-growing annual plant found across the globe. This member of the Euphorbiaceae family often grows in sidewalk cracks, gardens, and lawns, forming dense, spreading mats. Despite being commonly classified as a weed, the plant has a long history of use in traditional medicine and is currently the subject of scientific inquiry into its chemical properties.
Identifying Spotted Spurge
Spotted spurge is a prostrate plant that grows horizontally and close to the ground, radiating outward from a central taproot to form a mat. The reddish stems are covered with fine hairs and branch frequently, but they do not root at the nodes. When broken, the stems and leaves exude a milky-white, sticky latex sap, characteristic of the Euphorbia genus.
The small, oval-shaped leaves are arranged in opposite pairs along the stems. They often feature a distinguishing dark purple, maroon, or red spot in the center of the upper surface, which gives the plant its common name. The plant produces inconspicuous, tiny flowers grouped in clusters at the leaf axils, which develop into small, hairy, three-chambered seed capsules.
Traditional Applications in Folk Medicine
Across various cultures, Spotted Spurge has been utilized in folk medicine, primarily for treating ailments related to the digestive tract. Traditional practitioners valued the plant for its ability to address gastrointestinal irritation and was employed as a remedy for conditions such as diarrhea and dysentery. The leaves were often prepared as an infusion to manage these bowel disorders.
The traditional uses extended beyond internal applications. The milky sap was sometimes used topically for its astringent properties, applied to the skin to treat disorders like warts or carbuncles. In traditional Chinese medicine, the plant and its related species have been used to treat issues like hemoptysis, hematuria, and wound healing. These historical applications demonstrate an early recognition of the plant’s biological activity.
Active Compounds and Scientific Inquiry
Scientific inquiry investigates the chemical compounds responsible for the traditional efficacy of Spotted Spurge, which contains a rich profile of phytochemicals. Extracts from the plant contain significant levels of secondary metabolites, including flavonoids, tannins, and various terpenoids. These compounds are associated with a range of biological activities.
Specific lanostane-type triterpenoids have been isolated from Euphorbia maculata and evaluated for their biological effects. Preliminary studies have shown that extracts can inhibit inflammatory responses, such as ear edema in animal models. Furthermore, the plant’s chemical constituents exhibit antioxidant, antimicrobial, and anti-inflammatory properties, suggesting a scientific basis for its use against infections and inflammatory conditions. The presence of these bioactive compounds supports potential applications in pharmacology.
Safety and Handling Considerations
Spotted Spurge contains several compounds that require caution. The characteristic milky latex sap found throughout the stems and leaves is a known irritant. Contact with the sap can cause skin irritation, redness, swelling, and even blistering in susceptible individuals.
Improper preparation or ingestion of the plant material can lead to serious issues, as the sap is considered toxic. Oral exposure may cause a burning sensation in the mouth and throat, excessive drooling, vomiting, and diarrhea. The toxic principle is attributed to diterpene esters within the latex, which act as strong irritants to the digestive tract. Due to these risks, interaction with the plant should be handled with care, including wearing gloves during removal or harvesting, and avoiding internal use without expert guidance.

