Chronic diarrhea in older adults is defined as the passage of three or more loose or watery stools per day for a duration exceeding four weeks. This persistence signals an underlying issue more complex than a simple viral or bacterial infection, which typically resolves quickly. Causes are frequently multi-factorial, stemming from the interaction of multiple health conditions, numerous medications, and age-related changes in the digestive system.
Medication Side Effects and Dietary Sensitivities
Polypharmacy, the frequent use of multiple prescription drugs, is a major contributor to persistent loose stools in the elderly. Many medications irritate the intestinal lining or disrupt fluid absorption in the colon. For example, the diabetes drug metformin often causes increased gut motility and diarrhea.
Certain medications, including Angiotensin-Converting Enzyme (ACE) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs), can induce intestinal changes leading to chronic loose stools. Antacids containing magnesium draw excess water into the colon, resulting in osmotic diarrhea. Even selective serotonin reuptake inhibitors (SSRIs) can alter gut function by interfering with serotonin signaling in the digestive tract.
Dietary sensitivities also play a role in chronic digestive upset. The ability to produce the enzyme lactase, necessary to break down milk sugar, often diminishes with age, leading to lactose intolerance. When undigested lactose reaches the large intestine, it draws water into the bowel, causing osmotic diarrhea. Other forms of malabsorption, such as the inability to absorb certain fats or carbohydrates, can also result in fatty or watery stools.
Infections and Microbiome Disruptions
Changes in the microbial environment of the gut frequently cause persistent digestive issues. The bacterium Clostridioides difficile (C. diff) is a major cause of infectious diarrhea, especially severe in the elderly and healthcare settings. This organism produces toxins that damage the colon lining, resulting in watery, sometimes bloody, diarrhea.
The risk of C. diff infection increases following a course of antibiotics, which eliminate normal gut flora and allow the toxin-producing bacteria to flourish. Advanced age is a significant risk factor for severe complications. Small Intestinal Bacterial Overgrowth (SIBO) is another common cause of chronic diarrhea in older adults.
SIBO occurs when large intestine bacteria back up into the small intestine, interfering with digestion and nutrient absorption. This overgrowth leads to malabsorption, gas, bloating, and chronic loose stools. SIBO is often related to reduced stomach acid production, which naturally declines with age and is sometimes worsened by long-term use of acid-suppressing medications.
Structural and Motility-Related Causes
Some causes of chronic diarrhea relate to mechanical or physiological failure points. A common example is “overflow diarrhea,” paradoxically caused by severe fecal impaction—a blockage of hard stool in the rectum. The body responds by secreting fluid and mucus to break down the mass.
This liquid stool bypasses the blockage and leaks out, presenting as chronic, watery diarrhea or fecal incontinence. Overflow diarrhea is a mechanical problem often seen in individuals with slowed gut motility, which is exacerbated by immobility or certain pain medications. The underlying issue is severe constipation with leakage, not true diarrhea.
Age-related physiological changes also alter bowel habits. Slower gastrointestinal transit time can lead to constipation and, indirectly, to diarrhea (like SIBO). Additionally, the sphincter muscles that control stool passage may weaken over time. This reduced muscle control makes containing loose or urgent bowel movements more difficult for older individuals.
Recognizing Serious Symptoms and Seeking Help
While chronic loose stools have many manageable causes, certain symptoms warrant immediate medical evaluation to rule out serious conditions. The presence of blood in the stool, whether bright red or black and tarry, requires prompt consultation. Unexplained and continuous weight loss, especially with a loss of appetite, is another significant warning sign requiring investigation.
The older body is less resilient to fluid loss, making signs of dehydration a major concern. Symptoms like confusion, weakness, excessive thirst, and dark-colored urine indicate a need for urgent fluid replacement and medical attention. A persistent fever alongside diarrhea suggests an ongoing infection, such as C. diff, that must be diagnosed and treated quickly.

