What Causes Pupils That Are Not Round?

The pupil is the aperture in the center of the iris, functioning as the eye’s primary mechanism for regulating the amount of light that reaches the retina. In the human eye, this opening is almost round, allowing for efficient and uniform contraction and dilation in response to light intensity. The iris muscles control the pupil’s size, ensuring it remains centered and circular under normal conditions. Deviations from this standard round shape are known medically as dyscoria, indicating an underlying structural or functional issue. This irregularity can affect vision, light sensitivity, and the overall health of the eye.

Primary Types of Non-Circular Pupils

A misshapen pupil can present in several distinct forms, each pointing toward a specific origin. One recognizable non-circular shape is Coloboma, which gives the pupil a characteristic keyhole, teardrop, or notch-like appearance. This shape is caused by a sector of iris tissue being absent, often appearing at the lower-inner portion of the eye.

Dyscoria is the general classification for any abnormally shaped pupil, such as one that is oval, slit-like, or irregular. This irregularity suggests a problem with the structure of the iris itself, whether congenital or acquired.

The pupil may also be displaced from its typical central position, a condition called Corectopia. Corectopia involves a pupil that remains round but is noticeably shifted away from the center of the iris. A rare form of irregularity is Polycoria, where an individual appears to have multiple pupils in one eye. True polycoria requires each opening to have its own functioning sphincter muscle; most cases are actually pseudopolycoria, involving holes in the iris that lack independent muscle control.

Underlying Causes of Pupil Irregularity

The reasons behind irregular pupil shapes fall into three main categories: development, trauma, and disease. Congenital defects are established before birth. Coloboma is the most common example, resulting from the incomplete closure of the embryonic optic fissure during early fetal development. This failure to fuse leaves a gap in the iris tissue, creating the characteristic shape.

Non-round pupils can be acquired through trauma to the eye. Blunt force injury can cause tears in the iris sphincter muscle, which is responsible for constricting the pupil. A tear results in a permanently irregular, often ragged, pupil margin that cannot contract fully in the damaged area.

Iatrogenic or surgical causes also lead to irregularity, often occurring during ophthalmic procedures. Complications from cataract surgery or laser procedures can cause minor tears or structural changes to the iris tissue. These changes result in a pupil that is no longer round.

Disease processes involving inflammation or scarring can significantly alter the pupil’s contour. Conditions like uveitis or iritis, which are forms of inflammation inside the eye, can cause the iris to adhere to the lens behind it. This forms scar tissue known as posterior synechiae. These adhesions pull the iris tissue, preventing the pupil from dilating or constricting uniformly and creating an irregular edge.

Related Symptoms and Medical Evaluation Timing

A non-circular pupil often has functional consequences. A common associated symptom is photophobia, or increased sensitivity to light, which occurs when the irregular pupil cannot constrict sufficiently to filter bright light effectively. This failure to regulate light entry can also lead to glare and blurred vision, especially in bright environments.

The presence of an irregular pupil is often a stable, long-term finding, such as with a congenital coloboma or old traumatic injury. However, an acute and sudden change in pupil shape or size is a serious warning sign that requires immediate medical attention. Symptoms like new-onset pain, sudden vision loss, double vision, or a drooping eyelid occurring alongside a pupil change suggest a potentially life-threatening neurological event.

A sudden, fixed, and dilated pupil, particularly when accompanied by a severe headache or altered consciousness, can signal pressure on the third cranial nerve, possibly from a brain aneurysm. Conversely, a pupil that suddenly becomes small and irregular, combined with a drooping eyelid, may indicate a nerve pathway issue like Horner syndrome. This syndrome can be caused by a stroke or a tumor in the neck or chest. Reporting the exact timing of the change is important for a medical evaluation.

Diagnosis and Treatment Approaches

The medical evaluation for a non-circular pupil begins by establishing whether the irregularity is a new or long-standing condition. An ophthalmologist will use a slit lamp microscope to perform a magnified examination of the iris structure. This allows for the identification of tears in the sphincter muscle, the presence of scar tissue (synechiae), or developmental defects like coloboma.

If the non-round pupil is linked to a neurological concern, such as a suspected third nerve palsy or Horner syndrome, the diagnosis may require neuroimaging procedures like Magnetic Resonance Imaging (MRI) or Computed Tomography (CT). These scans are necessary to visualize the brain and surrounding blood vessels to rule out serious underlying causes like aneurysms or tumors.

Treatment depends on the cause and the impact on the patient’s function and vision. If the pupil irregularity is causing glare or light sensitivity, non-surgical options include specialty colored contact lenses to mask the defect and reduce incoming light. These lenses can also be used for cosmetic reasons.

For functional or cosmetic correction, surgical intervention may be considered, a procedure often referred to as pupilloplasty. This involves surgically reconstructing the iris tissue to make the pupil rounder or to repair tears and defects. Surgical repair is reserved for cases where the irregularity significantly impairs visual quality or causes persistent discomfort.