The human heart is an organ that continuously pumps blood through the body’s vast circulatory network. Understanding where this muscular pump is housed provides insight into its protection and function. The precise anatomical location of the heart involves a progression of nested compartments, moving from the largest general cavity to the smallest immediate protective layer.
The Thoracic Cavity
The broadest anatomical space containing the heart is the thoracic cavity. This is the second-largest hollow space in the body, providing a protective environment for several major organs. Its boundaries are defined by a bony and muscular cage, which includes the ribs on the sides, the sternum (breastbone) in the front, and the vertebral column at the back.
The muscular diaphragm forms the floor of this cavity, separating it from the abdominal contents below. Beyond the heart, this large compartment also contains the lungs, the trachea (windpipe), the esophagus, and the large blood vessels that connect to the heart.
The Mediastinum
Within the large thoracic cavity, the heart resides in a central subdivision known as the mediastinum. The mediastinum is the partition located medially between the two pleural cavities, which house the lungs. This central space extends vertically from the neck’s base down to the diaphragm and runs horizontally from the sternum to the vertebral column.
The mediastinum is further divided into superior and inferior sections, with the heart located specifically within the middle mediastinum. The heart’s position is slightly left of the body’s midline, with its apex, the pointed lower tip, resting near the fifth intercostal space. Other structures passing through the mediastinum include the major arteries and veins.
The Pericardial Sac
The final layer of protection and the most immediate surrounding structure is the pericardial sac, or pericardium. This is a double-walled, fibro-serous membrane that completely encloses the heart and the roots of the great vessels. The outer layer is the fibrous pericardium, a tough, inelastic layer of connective tissue that firmly anchors the heart within the middle mediastinum.
Inside the fibrous layer is the serous pericardium, which is divided into two layers: the parietal layer and the visceral layer. The space between these two serous layers is the pericardial cavity, which holds a small amount of serous fluid. This fluid functions to reduce friction as the heart contracts and relaxes. The sac’s semi-rigid nature also prevents the heart from overfilling with blood during periods of high volume.

