Hand, Foot, and Mouth Disease (HFMD) is a common and highly contagious viral illness that typically affects infants and young children. It is generally a mild infection that resolves on its own within seven to ten days, but it is known for causing characteristic, uncomfortable sores. This article focuses specifically on the visual appearance and associated discomfort of the lesions that develop inside the mouth and throat. The information provided here is for educational purposes only; always consult a healthcare professional for an accurate diagnosis and appropriate treatment plan.
Appearance of Oral and Throat Sores
The lesions that appear inside the mouth and throat are often the most painful symptom of Hand, Foot, and Mouth Disease, sometimes preceding the skin rash. These sores are sometimes referred to as herpangina, characterized by lesions located at the back of the mouth. They typically begin as small, distinct red spots, known as macules, that can be difficult to see without a close examination.
These initial spots rapidly evolve into small, fluid-filled blisters, or vesicles, often within a day. The sores are generally quite small, measuring only one to five millimeters in diameter. They are most commonly found on the soft palate, tonsils, uvula, and posterior pharynx.
As the condition progresses, the blisters rupture, leaving behind shallow, yellowish or grayish ulcers. A distinguishing feature of these ulcers is the pronounced red border or halo that surrounds the central, lighter-colored depression. This progression makes swallowing difficult and uncomfortable.
The number of throat lesions can vary significantly, from just a few isolated spots to numerous ulcers scattered across the posterior oral cavity. Because of their location and painful nature, these ulcers are frequently the primary source of distress in the early stages of the illness. The pain caused by these lesions can persist for several days before healing begins.
Accompanying Systemic Symptoms
HFMD frequently starts with systemic signs that precede the appearance of visible lesions. A sudden high fever is often the first indication of infection, typically accompanied by a general feeling of being unwell, known as malaise. This initial phase can resemble a common viral cold or flu, but it quickly transitions to symptoms centered on oral pain.
The presence of painful sores in the mouth and throat leads to significant discomfort, particularly a sore throat. This pain makes the act of swallowing extremely difficult, which can result in a refusal to eat or drink. In younger children, this difficulty is often observed as excessive drooling because they are reluctant to swallow their saliva.
Inadequate fluid intake due to swallowing pain is the most common concern with this illness, raising the risk of dehydration. Patients may also experience a reduced appetite and, in some cases, symptoms like abdominal pain or vomiting. Managing hydration and pain is critical during this stage of the disease.
Distinguishing Skin Rashes
The name Hand, Foot, and Mouth Disease describes the common distribution of the rash that occurs outside the oral cavity. Unlike the ulcers in the throat, which are almost universally painful, the skin rash tends to be less symptomatic, often presenting without itchiness. The lesions on the skin can appear as flat or slightly raised red spots that may or may not develop into blisters.
The most characteristic locations for the skin rash are the palms of the hands and the soles of the feet. These spots can sometimes have a grayish center, especially if they develop into small blisters. The rash may also appear on the buttocks, arms, or legs, especially in younger children.
The appearance of these external lesions helps differentiate HFMD from other viral illnesses that only cause throat sores. The skin lesions usually resolve without scarring, though the skin on the hands and feet may peel several weeks after the initial rash has cleared. This distinct rash pattern, combined with the classic oral ulcers, confirms the diagnosis.
Immediate Comfort Measures
Since there is no specific treatment for HFMD, care focuses on managing discomfort, especially the pain from the mouth and throat sores. Over-the-counter pain relievers, such as acetaminophen or ibuprofen, can be administered to help reduce fever and alleviate oral pain. It is important to follow dosing instructions carefully and to avoid giving aspirin to children due to the risk of Reye’s syndrome.
Hydration is a primary concern because of the painful swallowing, and cold items are often better tolerated than room-temperature liquids. Offering cold fluids, popsicles, sherbet, or ice chips can provide temporary numbing relief while ensuring fluid intake. Avoid acidic or spicy foods and drinks, such as citrus juices or sodas, as they can irritate the raw ulcers and intensify the pain.
Soft, bland foods that require minimal chewing, such as yogurt, mashed potatoes, or broth, can help maintain nutrition when eating is difficult. For severe oral pain, some healthcare providers may recommend topical oral anesthetics, though caution must be exercised in young children. These comfort measures aim to maintain hydration and ease pain until the viral infection clears.

