Fat stranding is a finding frequently noted on Computed Tomography (CT) scans, particularly those focusing on the abdomen and pelvis. It is not a diagnosis in itself but rather a non-specific radiological sign that points toward an underlying problem. This observation signifies a disease process in the nearby tissues. When a CT report mentions fat stranding, it indicates that the radiologist has identified a change in the appearance of normally uniform fatty tissue. This finding serves as an important clue, directing clinical attention and further investigation to a specific anatomical region where pathology is likely present.
What Fat Stranding Looks Like on a CT Scan
In its normal, healthy state, fatty tissue within the body contains a very low density, which causes it to appear dark gray or nearly black on a CT scan image. This uniform darkness is the expected background against which organs and muscle tissue are viewed. Fat stranding represents an alteration of this normal appearance, showing up as an increased density in the fat surrounding a structure or organ. The fat tissue transitions from being dark to appearing hazy, cloudy, or gray in the affected area.
The term “stranding” is used because this increased density often presents with a linear or streaky pattern, like faint, ill-defined strands running through the fat. This visual sign is sometimes described by radiologists as having a “ground-glass” or reticular appearance. The presence of this haziness signifies that the tissue’s density has increased, drawing it closer to the density of soft tissue or water.
The Biological Reason Behind the Hazy Appearance
The underlying cause for the hazy appearance of fat stranding is a localized acute inflammatory reaction occurring in the adipose tissue. It is a visible manifestation of the body’s response to irritation, infection, or injury in a nearby structure. When inflammation is triggered, the body initiates a process where fluid and immune cells are rushed to the site of the problem.
This influx of fluid is medically termed edema, involving the leakage of water and proteins from blood vessels into the spaces between the fat cells. Adipose tissue is normally low density, but the introduction of water-based edema dramatically increases the tissue’s overall density. Because CT scans measure tissue density, the higher water content causes the fat to appear lighter gray or hazy on the image instead of its usual dark shade.
Clinical Conditions Commonly Associated
The location of fat stranding is important for the physician, helping to narrow down possible medical conditions. Since fat stranding is a non-specific sign indicating only inflammation, its interpretation must be combined with the patient’s symptoms and other CT findings.
For example, stranding found next to the appendix strongly suggests acute appendicitis, especially if the appendix appears swollen or thickened. Pericolonic fat stranding (inflammation around the colon) is characteristic of acute diverticulitis, which involves the infection or inflammation of small pouches in the digestive tract. In diverticulitis, the fat stranding can sometimes be disproportionately more severe than the thickness of the colon wall.
When the fat stranding is concentrated around the pancreas, it indicates acute pancreatitis. It is also associated with inflammatory bowel disease, such as Crohn’s disease, where it signals an active flare in the adjacent bowel. Less common conditions, like epiploic appendagitis or omental infarction (localized fat injuries), also present with distinct patterns of fat stranding.

