What Does Hand, Foot, and Mouth Disease Look Like in Adults?

Hand, Foot, and Mouth Disease (HFMD) is a common viral illness most often associated with infants and young children. This highly contagious infection is caused by viruses primarily from the Enterovirus genus, such as Coxsackievirus A16. While HFMD frequently circulates in childcare settings, adults can also contract the illness, often after exposure to an infected child. The presentation of HFMD in adults can differ significantly from the mild course typically seen in younger patients.

Distinctive Symptoms in Adults

The initial phase of HFMD in adults often begins with pronounced prodromal symptoms. These flu-like indicators include a high fever, a severe headache, and general unwellness (malaise). A painful sore throat is also common during this initial stage, often preceding the appearance of any visible skin or mouth lesions.

The characteristic rash follows these systemic symptoms, but its presentation may vary considerably in adults. Lesions typically appear as flat, non-itchy red spots that may develop into small, fluid-filled blisters on the palms of the hands and soles of the feet. These blisters are frequently described as causing deep pain, a burning sensation, or extreme tenderness, especially when walking or using the hands.

In some adult cases, the rash may be more widespread, affecting the buttocks, trunk, or limbs, deviating from the classic hand-foot-mouth distribution. Some adults may experience herpangina, which is characterized by painful oral ulcers on the tongue, gums, and cheeks, without developing the classic rash on the hands and feet. These mouth sores can be severe enough to cause difficulty swallowing, which may lead to reduced food and fluid intake.

Severity and Typical Recovery Timeline

While HFMD is generally considered a self-limiting condition, the systemic symptoms, such as high fever and intense body aches, can be debilitating, often lasting for two to three days. The active phase, marked by painful rashes and mouth ulcers, typically runs its course over five to seven days.

Most adults recover fully from HFMD within seven to ten days without requiring specific medical treatment. However, a delayed effect known as onychomadesis can occur several weeks after the main symptoms resolve. This benign condition involves the temporary arrest of nail matrix activity, leading to the shedding or loss of one or more fingernails or toenails. The nail usually regrows on its own.

Home Management and Warning Signs

Managing HFMD symptoms at home focuses primarily on pain relief and maintaining adequate hydration. Over-the-counter pain relievers, such as acetaminophen or ibuprofen, can help manage the fever and reduce the generalized body pain and headache.

Hydration is particularly important due to the painful mouth sores that can make drinking difficult. Consuming cold liquids, such as water or electrolyte solutions, is recommended, and soft foods are easier to tolerate than hard or acidic items. Some adults may find relief using numbing mouthwashes or gels to temporarily alleviate the pain of oral ulcers.

While HFMD complications are rare, certain warning signs necessitate immediate medical attention. These include any signs of severe dehydration, such as dry mouth, sunken eyes, or significantly decreased urine output. Seek prompt care if symptoms involve the nervous system, which may present as a stiff neck, persistent or severe headache, confusion, or seizures. These neurological symptoms could indicate rare complications like viral meningitis or encephalitis.